Reaction between 3-hydroxy pyridine alkyl isocyanides and dialkyl acetylenedicarboxylate: synthesis of 4H-chromenes
الموضوعات : International Journal of Heterocyclic Chemistry
Mahsa Mahpeyma
1
(Department of Organic Chemistry, Karaj Branch, Islamic Azad university, Karaj, Iran)
Bita Mohtat
2
(Department of Organic Chemistry, Karaj Branch, Islamic Azad university, Karaj, Iran)
الکلمات المفتاحية: 3-hydroxy pyridine, dialkyl acetylene dicarboxylates, Alkyl isocyanide, multi component reaction, 4H-chromenes,
ملخص المقالة :
The reactive intermediate generated by the addition of tert-butyl and 1,1,3,3-tetramethyl butyl isocyanide and cyclohexyl isocyanide to dialkyl acetylenedicarboxylate was trapped by 3-hydroxy pyridine to produce highly functionalized 4H-chromenes in fairly good yields.
