Reaction between 3-hydroxy pyridine alkyl isocyanides and dialkyl acetylenedicarboxylate: synthesis of 4H-chromenes
محورهای موضوعی : Journal of Chemical Reactivity and SynthesisMahsa Mahpeyma 1 , Bita Mohtat 2
1 - Department of Organic Chemistry, Karaj Branch, Islamic Azad university, Karaj, Iran
2 - Department of Organic Chemistry, Karaj Branch, Islamic Azad university, Karaj, Iran
کلید واژه: 3-hydroxy pyridine, dialkyl acetylene dicarboxylates, Alkyl isocyanide, multi component reaction, 4H-chromenes,
چکیده مقاله :
The reactive intermediate generated by the addition of tert-butyl and 1,1,3,3-tetramethyl butyl isocyanide and cyclohexyl isocyanide to dialkyl acetylenedicarboxylate was trapped by 3-hydroxy pyridine to produce highly functionalized 4H-chromenes in fairly good yields.
