A Novel, Heterogeneous Catalyst for the One-Pot Synthesis of 1,8-Dioxodecahydroacridine Derivatives Under Solvent-Free Conditions
الموضوعات : International Journal of Heterocyclic ChemistryTayebeh Sanaeishoar 1 , Mitra Saremi 2
1 - Department of Chemistry, College of Science, Khouzestan Science and Research Branch, Islamic Azad University, Ahvaz, Iran
2 - Department of Chemistry, College of Science, Khouzestan Science and Research Branch, Islamic Azad University, Ahvaz, Iran
الکلمات المفتاحية: Solvent-free, 1, Multicomponent, One-pot synthesis, Hantzsch, 8-Dioxohexahydroacridine,
ملخص المقالة :
An efficient and environmental-friendly synthetic route to 1,8-dioxodecahydroacridines derivatives have been developed via multi-component one-pot Hantzsch reaction of various aldehydes and ammonium acetate with 2 equivalents dimedone in the presence of Phosphorus pentoxide supported on aluminaas catalyst under solvent-free conditions. The present approach offersseveral advantages such as short reaction times, easy isolation and purification of product, and safe, non-toxic, recyclable and economic use of catalyst.
