Antioxidant properties of various extract from selected wild Moroccan aromatic and medicinal species
الموضوعات :Ayoub Kasrati 1 , Chaima Alaoui Jamali 2 , Abdelaziz Abbad 3
1 - Faculty of Sciences, Semlalia, Cadi Ayyad University, Marrakesh, Morocco
2 - École Normale Supérieure, Université Abdelmalek Essaadi, Tetouan, Morocco
3 - Faculty of Sciences, Semlalia, Cadi Ayyad University, Marrakesh, Morocco
الکلمات المفتاحية: aromatic and medicinal plants, phenols, Antioxidant properties, Moroccan, Flavonoids, extracts,
ملخص المقالة :
Antioxidant properties of various extracts from different wild Moroccan aromatic and medicinal plants (Achillea ageratum L., Salvia officinalis L., Thymus satureoiedes Cosson., Mentha suaveolens subsp. timija (Briq.) Harley and Cotula cinerea Del.) were examined by applying DPPH free radical-scavenging activity, β-Carotene/linoleic acid bleaching and reducing power assays. Total phenol and flavonoid contents of the extracts were also determined. Antioxidant activity was compared with that of synthetic antioxidants (Butylated hydroxytoluene (BHT) and Quercetin). Overall, the highest antioxidant properties were shown by the hot water and methanolic extracts obtained from all species studied. The hot water extract of M. suaveolens subsp. timija (Briq.) presented the best contribution in DPPH and reducing power assays (IC50 = 14.04 ± 0.14 and 17.36 ± 0.1 µg/mL, respectively) which was significantly associated with its high phenolic content (134.49 ± 2.14 µg GAE/mg extract). However, in β-carotene-linoleic acid bleaching assay, the hot water extract of S. officinalis L. was the most effective with an IC50 value of 14.49 ± 0.40 µg/mL. These findings provide new information on the considerable potential of the five Moroccan medicinal and aromatic plants as a source of natural antioxidant substances. Therefore, they could be suitable for using as antioxidative additives in the food and pharmaceutical industries.
Addai, Z.R., Abdullah, A., Mutalib, S.A., 2013. Effect of extraction solvents on the phenolic content and antioxidant properties of two papaya cultivars. J. Med. Plants Res. 7(46), 3354-3359.
Alaoui Jamali, C., El Bouzidi, L., Bekkouche, K., Lahcen, H., Markouk, M., Wohlmuth, H., Leach, D., Abbad, A., 2012. Chemical composition and antioxidant and anticandidal activities of essential oils from different wild Moroccan Thymus species. Chem. Biodivers. 9(6), 1188-1197.
Ali, I.B.E., Bahri, R., Chaouachi, M., Boussaid, M., Harzallah-Skhiri, F., 2014. Phenolic content, antioxidant and allelopathic activities of various extracts of Thymus numidicus Poir. organs. Ind. Crops Prod. 62, 188-95.
Alimpić, A., Knežević, A., Milutinović, M., Stević, T., Šavikin, K., Stajić, M., Markovićb, S., Marina, P.D., Matevski, V., Duletić-Laušević, S., 2017. Biological activities and chemical composition of Salvia amplexicaulis Lam. extracts. Ind. Crops Prod. 105, 1-9.
Arabshahi-Delouee, S., Urooj, A., 2007. Antioxidant properties of various solvent extracts of mulberry (Morus indica L.) leaves. Food Chem. 102(4), 1233-1240.
Bamoniri, A., Ebrahimabadi, A.H., Mazoochi, A., Behpour, M., Kashi, F.J., Batooli, H., 2010. Antioxidant and antimicrobial activity evaluation and essential oil analysis of Semenovia tragioides Boiss. from Iran. Food Chem. 122(3), 553-558.
Baricevic, D., Sosa, S., Della Loggia, R., Tubaro, A., Simonovska, B., Krasna, A., Zupancic, A., 2001. Topical anti-inflammatory activity of Salvia officinalis L. leaves: the relevance of ursolic acid. J. Ethnopharmacol. 75, 125-132.
Belfeki, H., Mejri, M., Hassouna, M., 2016. Antioxidant and anti-lipases activities in vitro of Mentha viridis and Eucalyptus globulus extracts. Ind. Crops Prod. 89, 514-521.
Bellakhdar, J., 2006. Plantes médicinales au Maghreb et soins de base: précis de phytothérapie moderne, Editions le Fennec, Casablanca. pp. 386.
Benabdallah, A., Rahmoune, C., Boumendjel, M., Aissi, O., Messaoud, C., 2016. Total phenolic content and antioxidant activity of six wild Mentha species (Lamiaceae) from northeast of Algeria. Asian Pac. J. Trop. Biomed. 6(9), 760-766.
Bensizerara, D., Menasria, T., Melouka, M., Cheriet, L., Chenchouni, H., 2013. Antimicrobial activity of xerophytic plant (Cotula cinerea Delile) extracts against some pathogenic bacteria and fungi. Jordan J. Biol. Sci. 6(4), 266-271.
Bouajaj, S., Benyamna, A., Bouamama, H., Romane, A., Falconieri, D., Piras, A., Marongiu, B., 2013. Antibacterial, allelopathic and antioxidant activities of essential oil of Salvia officinalis L. growing wild in the Atlas Mountains of Morocco. Nat. Prod. Res. 27(18), 1673-1676.
Boussouf, L., Boutennoune, H., Kebieche, M., Adjeroud, N., Al-Qaoud, K., Madani, K., 2017. Anti-inflammatory, analgesic and antioxidant effects of phenolic compound from Algerian Mentha rotundifolia L. leaves on experimental animals. S. Afr. J. Bot. 113, 77-83.
Bruneton, J., 1999. (Ed.), Pharmacognosy, Phytochemistry, Medicinal Plants (Second Ed.), Lavoisier Publishing, Paris, pp. 540-544.
El Bouzidi, L., Abbad, A., Fattarsi, K., Hassani, L., Leach, D., Markouk, M., Legendre L., Bekkouche, K., 2011. Chemical composition and anticandidal properties of the essential oil isolated from aerial parts of Cotula cinerea: a rare and threatened medicinal plant in Morocco. Nat. Prod. Commun. 6(10), 1491-1494.
El Bouzidi, L., Alaoui Jamali, C., Bekkouche, K., Hassani, L., Wohlmuth, H., Leach, D., Abbad, A., 2013. Chemical composition, antioxidant and antimicrobial activities of essential oils obtained from wild and cultivated Moroccan Thymus species. Ind. Crops Prod. 43, 450-456.
Et-Touys, A., Fellah, H., Mniouil, M., Bouyahya, A., Dakka, N., Abdennebi, E. H., Sadak, A., Bakri, Y., 2016. Screening of antioxidant, antibacterial and antileishmanial activities of Salvia officinalis L. extracts from Morocco. Br. Microbiol. Res. J. 16, 1-10.
Fellah, S., Diouf, P.N., Petrissans, M., Perrin, D., Romdhane, M., Abderrabba, M., 2006. Chemical composition and antioxidant properties of Salvia officinalis L. oil from two culture sites in Tunisia. J. Essent. Oil Res. 18(5), 553-556.
Gonçalves, S., Gomes, D., Costa, P., Romano, A., 2013. The phenolic content and antioxidant activity of infusions from Mediterranean medicinal plants. Ind. Crops Prod. 43, 465-471.
Gouveia, S., Castilho, P.C., 2011. Antioxidant potential of Artemisia argentea L'Hér alcoholic extract and its relation with the phenolic composition. Food Res. Int. 44(6), 1620-1631.
Hayouni, E.A., Chraief, I., Abedrabba, M., Bouix, M., Leveau, J.Y., Mohammed, H., Hamdi, M., 2008. Tunisian Salvia officinalis L. and Schinus molle L. essential oils: their chemical compositions and their preservative effects against Salmonella inoculated in minced beef meat. Int. J. Food Microbiol. 125, 242-251.
Huang, D.J., Ou, B.X., Prior, R.L., 2005. The chemistry behind antioxidant capacity assays. J. Agric. Food Chem. 53(6), 1841-1856.
Imanshahidi, M., Hosseinzadeh, H., 2006. The pharmacological effects of Salvia species on the central nervous system. Phytother. Res. 20, 427-437.
Issa, A.Y., Volate, S.R., Wargovich, M.J., 2006. The role of phytochemicals in inhibition of cancer and inflammation: new directions and perspectives. J. Food Compos. Anal. 19, 405-419.
Jang, R.W., Laue, K.M., Hon, P.M., Mak, T.C.W., Woo, K.S., Fung, K.P., 2005. Chemistry and biological activities of caffeic acid derivatives from Salvia miltiorrhiza. Curr. Med. Chem. 12, 273-276.
Kamatou, G.P.P., Viljoen, A.M., Steenkamp, P., 2010. Antioxidant, anti-inflammatory activities and HPLC analysis of South African Salvia species. Food Chem. 119, 684-688.
Kamkar, A., Javan, A.J., Asadi, F., Kamalinejad, M., 2010. The antioxidative effect of Iranian Mentha pulegium extracts and essential oil in sunflower oil. Food Chem. Toxicol. 48(7), 1796-1800.
Kasrati, A., Alaoui Jamali, C., Fadli, M., Bekkouche, K., Hassani, L., Wohlmuth, H., Leach, D., Abbad, A., 2014. Antioxidative activity and synergistic effect of Thymus saturejoides Coss. essential oils with cefixime against selected food-borne bacteria. Ind. Crops Prod. 61, 338-344.
Kocak, M. S., Sarikurkcu, C., Cengiz, M., Kocak, S., Uren, M.C., Tepe, B., 2016. Salvia cadmica: Phenolic composition and biological activity. Ind. Crops Prod. 85, 204-212.
Loizzo, M.R., Tundis, R., Menichini, F., Saab, A.M., Statti, G.A., Menichini, F., 2007. Cytotoxic activity of essential oils from Labiatae and Lauraceae families against in vitro human tumor models. Anticancer Res. 27(5), 3293-3299.
Markouk, M., Redwane, A., Lazrek, H.B., Jana. M., Benjama, A., 1999. Antibacterial activity of Cotula cinerea extracts. Fitoterapia 70, 314-316.
McCord, J.M., 2000. The evolution if free radicals and oxidative stress. Am. J. Med. 108, 652-659.
Miraliakbari, H., Shahidi, F., 2008. Antioxidant activity of minor components of tree nut oils. Food Chem. 111, 421-427.
Mohammadhosseini, M., 2017. The ethnobotanical, phytochemical and pharmacological properties and medicinal applications of essential oils and extracts of different Ziziphora species. Ind. Crops Prod. 105, 164-192.
Mohammadhosseini, M., Sarker, S.D., Akbarzadeh, A., 2017. Chemical composition of the essential oils and extracts of Achillea species and their biological activities: A review. J. Ethnopharmacol. 199, 257-315.
Moll, M., 1998. Additifs alimentaires et auxiliaires technologique. Ed. DUNOD, Paris, pp. 89-99.
Ordon, J.D., Gomez, M.A., Vattuone, M.I., 2006. Antioxidant activities of Sechium edule (Jacq.) Swartz extracts. Food Chem. 97, 452-458.
Oyaizu, M., 1986. Studies on product of browning reaction prepared from glucose amine. Jap. J. Nutr. 44, 307-315.
Padmini, E., Valarmathi, A., Rani, M.U., 2010. Comparative analysis of chemical composition and antibacterial activities of Mentha spicata and Camellia sinensis. Asian J. Exp. Biol. Sci. 1(4), 772-778.
Pereira, C.G., Barreira, L., da Rosa Neng, N., Nogueira, J.M.F., Marques, C., Santos, T.F., Varela, J., Custódio, L., 2017. Searching for new sources of innovative products for the food industry within halophyte aromatic plants: In vitro antioxidant activity and phenolic and mineral contents of infusions and decoctions of Crithmum maritimum L. Food Chem. Toxicol. 107, 581-589.
Pietta, P.G., 2000. Flavonoids as antioxidants. J. Nat. Prod. 63(7), 1035-1042.
Prior, R.L., 2004. Absorption and Metabolism of Anthocyanins: Potential Health Effects. In: Meskin, M., Bidlack, W.R., Davies, A.J., Lewis, D.S., Randolph, R.K. (Eds.), Phytochemicals: Mechanisms of Action, CRC Press, Boca Raton, FL, p. 1.
Ramchoun, M., Harnafi, H., Alem, C., Büchele, B., Simmet, T., Rouis, M., Atmani, F., Amrani, S., 2012. Hypolipidemic and antioxidant effect of polyphenol-rich extracts from Moroccan thyme varieties. ESPEN J. 7(3), 119-124.
Sacchetti, G., Maietti, S., Muzzoli, M., Scaglianti, M., Manfredini, S., Radice, M., Bruni, R., 2005. Comparative evaluation of 11 essential oils of different origin as functional antioxidants, antiradicals and antimicrobials in foods. Food Chem. 91, 621-632.
Sahin, F., Güllüce, M., Daferera, D., Sökmen, A., Sökmen, M., Polissiou, M., Agar, G., Özer, H., 2004. Biological activities of the essential oils and methanol extract of Origanum vulgare ssp. vulgare in the Eastern Anatolia region of Turkey. Food Control 15, 549-557.
Sarikurkcu, C., Ozer, M.S., Eskici, M., Tepe, B., Can, S., Mete, E., 2010. Essential oil composition and antioxidant activity of Thymus longicaulis C. Presl subsp. longicaulis var. longicaulis. Food Chem. Toxicol. 48, 1801-1805.
Schlesier, K., Harwat, M., Bohm, V., Bitsch, R., 2002. Assessment of antioxidant activity by using different in vitro methods. Free Radic. Res. 36, 177-187.
Şenol, F.S., Orhan, I., Celep, F., Kahraman, A., Doğan, M., Yilmaz, G., Şener, B., 2010. Survey of 55 Turkish Salvia taxa for their acetylcholinesterase inhibitory and antioxidant activities. Food Chem. 120(1), 34-43.
Sivasothy, Y., Chong, W.K., Hamid, A., Eldeen, I.M., Sulaiman, S.F., Awang, K., 2011. Essential oils of Zingiber officinale var. rubrum Theilade and their antibacterial activities. Food Chem. 124, 514-517.
Skotti, E., Anastasaki, E., Kanellou, G., Polissiou, M., Tarantilis, P.A., 2014. Total phenolic content, antioxidant activity and toxicity of aqueous extracts from selected Greek medicinal and aromatic plants. Ind. Crops Prod. 53, 46-54.
Sultana, B., Anwar, F. Ashraf, M., 2009. Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts. Molecules 14(6), 2167-2180.
Teixeira, B., Marques, A., Cristina Ramos, C., Serrano, C., Matos, O., Neng, N.R., Nogueira, J.M.F., Saraiva, J.A., Nunes, M.L., 2013. Chemical composition and bioactivity of different oregano (Origanum vulgare) extracts and essential oil. J. Sci. Food Agric. 93, 2707-2714.
Tepe, B., Daferera, D., Tepe, A.S., Polissiou, M., Sokmen, A., 2007. Antioxidant activity of the essential oil and various extracts of Nepeta flavida Hub.-Mor. from Turkey. Food Chem. 103(4), 1358-1364.
Toma, M., Vinatoru, M., Paniwnyk, L. Mason, T.J., 2001. Investigation of the effects of ultrasound on vegetal tissues during solvent extraction. Ultrason. Sonochem. 8(2), 137-142.
Toplan, G.G., Kurkcuoglu, M., Goger, F., İşcan, G., Ağalar, H.G., Mat, A., Baser, K.H.C., Koyuncu, M., Sarıyar, G., 2017. Composition and biological activities of Salvia veneris Hedge growing in Cyprus. Ind. Crops Prod. 97, 41-48.
Vieira, L.M., Kijjoa, A., Pereira, J., Gedris, T.E., Herz, W., 1997. Germacranes and flavonoids from Achillea ageratum. Phytochemistry 45(1), 111-115.
Xiu-Qin, L., Chao, J., Yan-Yan, S., Min-Li, Y., Xiao-Gang, C., 2009. Analysis of synthetic antioxidants and preservatives in edible vegetable oil by HPLC/TOF-MS. Food Chem. 113(2), 692-700.
Zengin, G., Sarikurkcu, C., Aktumsek, A., Ceylan, R., 2014. Sideritis galatica Bornm.: a source of multifunctional agents for the management of oxidative damage, Alzheimer’s and diabetes mellitus. J. Funct. Foods 11, 538-547.
