The relationship between oxygen radical absorbance capacity (ORAC) index and elevated blood pressure in overweight or obese subjects compared to normal-weight subjects

الموضوعات : Food and Health

Zahra Madani ¹ , Abolghassem Djazayery ² , Ariyo Movahedi ³ , Majid Karandish ⁴

1 - Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
2 - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Science, Tehran, Iran
3 - Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
4 - Nutrition and Metabolic Diseases Research Centre, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

تاريخ الإرسال : 10 السبت , محرم, 1442 تاريخ التأكيد : 19 الخميس , ربيع الأول, 1442 تاريخ الإصدار : 04 الجمعة , ربيع الأول, 1441

الکلمات المفتاحية: Oxygen Radical Absorption Capa, systolic pressure, diastolic pressure, Obesity, Overweight,

ملخص المقالة :

Obesity is an important preventable disease and increases the chance of developing some chronic diseases like hypertension which is related to many factors including oxidative stress. Dietary antioxidants protect the body against oxidative stress. The purpose of this study was to evaluate the potential association of dietary oxygen radical absorbance capacity (ORAC) index with blood pressure in overweight or obese subjects compared to normal-weight subjects. In a cross-sectional study on 157 adult females and males from students and staff of Science and Research Branch of Islamic Azad University (SRBIAU) of Tehran that classified in two groups of normal weight and overweight or obese were evaluated. Demographic and validated food frequency questionnaires (FFQ) were completed and individuals' weight and height information were measured using the BIA. The systolic and diastolic pressure was recorded by the Automatic Blood Pressure monitor. Dietary antioxidant was estimated based on the ORAC index of selected foods reported by the Nutrient Data Laboratory of the United States Department of Agriculture (USDA). The results showed that there was a significant difference between the normal and overweight or obese groups in terms of body mass index, systolic and diastolic pressure (p=0.0001). Also, the ORAC index was higher in normal individuals than the case group, but it was not significant (p=0.222). There was also an inverse correlation between dietary ORAC, systolic and diastolic pressure in both groups, and only in the normal weight group, the association between systolic pressure and the dietary ORAC index was significant (p=0.04). The findings of the present study suggested that the dietary ORAC index was inversely associated with systolic and diastolic pressure in both subjects.

المصادر:

1. Salehi-Abargouei A, Akbari F, Bellissimo N, Azadbakht L. Dietary diversity score and obesity: A systematic review and meta-analysis of observational studies. European Journal of Clinical Nutrition. 2016; 70:1–9.


2. Anumba D, Jivraj S. Antenatal disorders for the MRCOG and beyond. W.B. Saunders; 2016. p.135–8.


3. Chooi YC, Ding C, Magkos F. The epidemiology of obesity. Metabolism. 2019;92:6–10.


4. WHO. 10 Facts on obesity. World Health Organization. 2017. Available from: https://www.who.int/features/factfiles/obesity/en.


5. Keaney JF, Larson MG, Vasan RS, Wilson PWF, Lipinska I, Corey D, et al. Obesity and systemic oxidative stress: Clinical correlates of oxidative stress in the Framingham study. Arteriosclerosis, Thrombosis, and Vascular Biology. 2003;23(3):434–9.


6. Olusi SO. Obesity is an independent risk factor for plasma lipid peroxidation and depletion of erythrocyte cytoprotectic enzymes in humans. International Journal of Obesity. 2002;26(9):1159–64.


7. Huang CJ, McAllister MJ, Slusher AL, Webb HE, Mock JT, Acevedo EO. Obesity-related oxidative stress: The impact of physical activity and diet manipulation. Sport Medicine-Open. 2015;1:32.


8. Lassègue B, Griendling KK. Reactive oxygen species in hypertension: An update. American Journal of Hypertension. 2004;17:852–60.


9. Rodrigo R, Passalacqua W, Araya J, Orellana M, Rivera G. Implications of oxidative stress and homocysteine in the  pathophysiology of essential  hypertension. Journal of Cardiovascular Pharmacology. 2003;42:453–61.


10. Paravicini TM, Touyz RM. Redox signaling in hypertension. Cardiovascular Research. 2006;71:247–58.


11. Wang L, Manson JE, Gaziano JM, Buring JE, Sesso HD. Fruit and vegetable intake and the risk of hypertension in middle-aged and older women. American Journal of Hypertension. 2012;25(2):180–9.


12. Damasceno MMC, De Araújo MFM, Freire de Freitas RWJ, de Almeida PC, Zanetti ML. The association between blood pressure in adolescents and the consumption of fruits, vegetables and fruit juice - an exploratory study. Journal of Clinical Nursing. 2011;20(11–12):1553–60.


13. Haytowitz D, Bhagwat S. USDA Database for the oxygen radical absorbance capacity (ORAC) of selected foods, release 2. U.S. Department of Agriculture. 2010;10–48. Available from: http://www.orac-info-portal.de/download/ORAC_R2.pdf.


14. Galasko DR, Peskind E, Clark CM, Quinn JF, Ringman JM, Jicha GA, et al. Antioxidants for Alzheimer disease: A randomized clinical trial with cerebrospinal fluid biomarker measures. Archives of Neurology. 2012;69(7):836–41.


15. Carocho M, Ferreira ICFR, Morales P, Soković M. Antioxidants and prooxidants: Effects on health and aging 2018. Oxidative Medicine and Cellular Longevity. 2019; 2019:ID 7971613.


16. Mirmiran P, Esfahani FH, Mehrabi Y, Hedayati M, Azizi F. Reliability and relative validity of an FFQ for nutrients in the Tehran lipid and glucose study. Public Health Nutrition. 2010;13(5):654–62.


17. Ogedegbe G, Pickering T. Principles and techniques of blood pressure measurement. Cardiology Clinics. 2010;28(4):571–86.


18. Michaëlsson K, Wolk A, Melhus H, Byberg L. Milk, fruit and vegetable, and total antioxidant intakes in relation to mortality rates: Cohort studies in women and men. American Journal of Epidemiology. 2017;185(5):345–61.


19. Li C, Huang WY, Wang XN, Liu WX. Oxygen radical absorbance capacity of different varieties of strawberry and the antioxidant stability in storage. Molecules. 2013;18(2):1528–39.


20. Zhao X, Iwamoto T, Carey EE. Antioxidant capacity of leafy vegetables as affected by high tunnel environment, fertilisation and growth stage. Journal of the Science of Food and Agriculture. 2007;87(14):2692–9.


21. Myint PK, Luben RN, Wareham NJ, Khaw KT. Association between plasma vitamin C concentrations and blood pressure in the European prospective investigation into cancer-norfolk population-based study. Hypertension. 2011;58(3):372–9.  


22. Yanagisawa A, Suzuki K, Kimura A, Ito Y, Hamajima N, Inoue T. Possible protective effect of serum β-carotene levels on the association between interleukin-1B C-31T polymorphism and hypertension in a Japanese population. Clinical Nutrition. 2009;28(2):198–202.


23. Li B, Li F, Wang L, Zhang D. Fruit and vegetables consumption and risk of hypertension: A meta-analysis. Journal of Clinical Hypertension. 2016;18:468–76.


24. Borgi L, Muraki I, Satija A, Willett WC, Rimm EB, Forman JP. Fruit and vegetable consumption and the incidence of hypertension in three prospective cohort studies. Hypertension. 2016;67(2):288–93.


25. Kim J, Kim J. Association between fruit and vegetable consumption and risk of hypertension in middle-aged and older Korean adults. Journal of the Academy of Nutrition and Dietetics. 2018;118(8):1438-1449.e5.


26. Villaverde P, Lajous M, MacDonald C-J, Fagherazzi G, Bonnet F, Boutron-Ruault M-C. High dietary total antioxidant capacity is associated with a reduced risk of hypertension in French women. Nutrition Journal. 2019;18(1):31.


27. Manna P, Jain SK. Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: Causes and therapeutic strategies. Metabolic Syndrome and Related Disorders. 2015;13(10):423–44.


28. Matsuda M, Shimomura I. Increased oxidative stress in obesity: Implications for metabolic syndrome, diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer. Obesity Research and Clinical Practice. 2013;7(5):e330-41


29. Ito F, Sono Y, Ito T. Measurement and clinical significance of lipid peroxidation as a biomarker of oxidative stress: Oxidative stress in diabetes, atherosclerosis, and chronic inflammation. Antioxidants. 2019;25;8(3).


30. Loperena R, Harrison DG. Oxidative stress and hypertensive diseases. Medical Clinics of North America. 2017;101:169–93.


31. Siti HN, Kamisah Y, Kamsiah J. The role of oxidative stress, antioxidants and vascular inflammation in cardiovascular disease (a review). Vascular Pharmacology. 2015;71:40–56.


32. Dandona P, Mohanty P, Ghanim H, Aljada A, Browne R, Hamouda W, et al.  The Suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation. The Journal of Clinical Endocrinology and Metabolism. 2001;86(1):355–62.


33. Nayer A, Ortega LM. Catastrophic antiphospholipid syndrome: A clinical review. Journal of Nephropathology. 2014;3:9–17.


34. Nasri H. Hypertension and renal failure with right arm pulse weakness in a 65 years old man. Journal of Nephropathology. 2012;1(3):130–3.


35. Nasri H, Baradaran A, Rafieian-Kopaei M. Oxidative stress and hypertension: Possibility of hypertension therapy with antioxidants. Journal of Research in Medical Sciences. 2014;19(4):358–67.