International Journal of Bio-Inorganic Hybrid Nanomaterials: 2 (2)

Open Access Article

1 - A Review of the properties, synthesis and application of Nano Hydroxyapatite

Nano-Hydroxyapatite (nHAP) is a very valuable mineral that is widely used in tissueengineering as well as bone and dental repair. Moreover, it is a major component of bone, enamel anddentin that can interact effectively with healing tissues due to its high biocompatibil More

Nano-Hydroxyapatite (nHAP) is a very valuable mineral that is widely used in tissueengineering as well as bone and dental repair. Moreover, it is a major component of bone, enamel anddentin that can interact effectively with healing tissues due to its high biocompatibility. It is important tonote that the purpose of its medical application can be identified based on the structure and synthesisof HAP. This study aimed to efficiently review all the previously conducted studies on synthesis andapplication of nHAP over the years of researchers' efforts and present the results for optimizingbiocompatible material synthesis. Manuscript profile

Open Access Article

2 - CuMn2O4 nanostructures: Facial synthesis, structural,magnetical, electrical characterization and activation energy calculation

The work is the report about stearic acid sol-gel synthesis method, magnetically, electricalcharacterization and activation energy of copper manganese oxide nanostructures. The CuMn2O4nanostructures are synthesized at a temperature of 600°C using the sol-gel method. More

The work is the report about stearic acid sol-gel synthesis method, magnetically, electricalcharacterization and activation energy of copper manganese oxide nanostructures. The CuMn2O4nanostructures are synthesized at a temperature of 600°C using the sol-gel method. The structuralanalysis using X-ray diffraction (XRD) and Scherrer equation show that the crystallite size of CuMn2O4is about 23.0 nm. The activation energy value is measured by temperature-programmed reduction(TPR) analysis at three heating rates of 10, 15 and 20 °C/min and Kissinger equation .The Ea value is28.1 kJ/mol. Vibrating sample magnetometer (VSM) analysis of the nanostructures indicates moderateferromagnetic properties. Examination of the dielectric properties by the LCR meter indicates thesemiconducting property of the nanostructure. The highest conductivity increase was in the frequencyof 308 MHz equal to 70.7 μS. Therefore, the CuMn2O4 nanostructures are potential candidates in fuelcells, telephones, loudspeakers and transformers due to their properties and convenience, non-toxicand environmentally friendly production methods. Manuscript profile

Open Access Article

3 - Mono-Mono-Mono and Bi-Bi-Bi three-layer graphene systems’ optical conductivity

Investigating the longitudinal optical conductivity of graphene systems, which is the mostimportant property for opto-electronic devices, for three-layer graphene systems theoretically andnumerically is the main purpose of this study. Each layer can be mono- or bi-layer More

Investigating the longitudinal optical conductivity of graphene systems, which is the mostimportant property for opto-electronic devices, for three-layer graphene systems theoretically andnumerically is the main purpose of this study. Each layer can be mono- or bi-layer graphene. Separationbetween layers has been denoted by d, selected to be about ten nanometers. The carrier densities ineach layer can be tuned by changing gate voltage. In these two dimensional layered structures; themain contributions to the optical conductivity are from the intra- and inter-band transition channels in asame layer. In this paper the graphene structure is described primarily, and the three-layer graphenesystems with composes of mono-mono-mono and bi-bi-bi has been defined. Using dielectric andelectron density-density correlation tensors, the imaginary part of dielectric function for the three-layergraphene systems are calculated and optical conductivities are plotted as a function of photon energiesin different broadening widths, for final stages. Manuscript profile

Open Access Article

4 - Investigation the Mechanism of Interaction between Inhibitor ALISERTIB with Protein Kinase A and B Using Modeling, Docking and Molecular Dynamics Simulation

The high level of conservation in ATP-binding sites of protein kinases increasingly demandsthe quest to find selective inhibitors with little cross reactivity. Kinase kinases are a recently discoveredgroup of Kinases found to be involved in several mitotic events. These More

The high level of conservation in ATP-binding sites of protein kinases increasingly demandsthe quest to find selective inhibitors with little cross reactivity. Kinase kinases are a recently discoveredgroup of Kinases found to be involved in several mitotic events. These proteins represent attractivetargets for cancer therapy with several small molecule inhibitors undergoing different phase of clinicaltrials. Alisertib, a synthetic inhibitor of Kinase kinases, acts as an ATP-competitive compound whichhas been proved to be selective for Kinase A and is currently being evaluated in the phase I trial forpatients with advanced solid tumors. However, the structural details on the selectivity of Alisertib towardsKinase-A over Kinase B are still not resolved. To investigate the structural details of this selectivity, thecomplexes of Kinase A and B with Alisertib were modeled and evaluated using molecular dynamicssimulation and docking techniques. The predicted free energy for the binding of Alisertib to Kinase Aand B suggests stronger interactions between Alisertib and Kinase A. Results also indicate that thereare a strong attraction and anion- pi stacking interaction between the Phe144 in Kinase A and CLBBatom and benzazepine scaffold of Alisertib. As well as it seems a desired anion-pi stacking interactionwas created between the carboxyl group of the side chain of Asp274 and fluoro methoxyphenyl ring ofAlisertib. Furthermore, Kinase kinases contain a conserved hydrophobic ligand-binding pocket that ishighly involved in ligand binding specificity. Taken together it seems that the mentioned difference in thebinding pockets of Kinase A and B are the key factors responsible for selectivity. Manuscript profile

Open Access Article

5 - Investigating the Longitudinal Optical Conductivity in Three-Layer Graphene Systems with Composes Mono-Bi-Bi and Bi-Mono-Bi and Bi-Bi-Mono

The longitudinal optical conductivity is the most important property for graphene-baseddevices. So investigating this property for spatially separated few-layer graphene systems analyticallyand numerically is the main purpose of our study. Each layer can be mono- or bi- More

The longitudinal optical conductivity is the most important property for graphene-baseddevices. So investigating this property for spatially separated few-layer graphene systems analyticallyand numerically is the main purpose of our study. Each layer can be mono- or bi-layer graphene. Thedensity-density correlation function has been screened by the dielectric function using the randomphase approximation, which includes the inter-layer Coulomb coupling. By using Kronecker delta anddielectric tensors, the optical conductivity, is calculated, and plotted as a function of photon energyfor three-layer graphene systems with composes mono-bi-bi, bi-mono-bi, and bi-bi-mono in differentbroadening widths. In the presence of the potential function between the layers, the carrier densities ineach layer can be tuned respectively. In these two dimensional layered structures; the main contributionsto the optical conductivity are from the intra- and inter-band transition channels in a same layer. Manuscript profile

Open Access Article

6 - Removal of Cationic Dyes from Aqueous Solution using Organomodified Nanoclay

In this work, organomodified nanoclay has been used as the adsorbent for the removal ofbasic blue 41, cationic dye from an aqueous solution. The performance of the organomodified nanoclaywas tested in a batch system under varying pH (2–12), adsorbent dosage (0.1&n More

In this work, organomodified nanoclay has been used as the adsorbent for the removal ofbasic blue 41, cationic dye from an aqueous solution. The performance of the organomodified nanoclaywas tested in a batch system under varying pH (2–12), adsorbent dosage (0.1–2 g L-1), initial dyeconcentration (10–60 mgL-1), and contact time (5- 100 min). The best conditions were achieved at pH of7, 1 gL-1 of adsorbent at contact time of 60 min. The results indicate that nanoclay adsorbs the cationicdye efficiently and could be employed in wastewater treatment for the removal of dyes that may beharmful to human health. Manuscript profile

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