Phytochemical characteristics of Galeopsis ladanum subsp. angustifolia (Ehrh. ex Hoffm.) Gaudin collected in Abruzzo region (Central Italy) with chemotaxonomic and ethnopharmacological implications

Subject Areas : Analytical Assessments of Bioactive Compounds

Claudio Frezza ¹ , Alessandro Venditti ² , Ilaria Serafini ³ , Alessandra Carassiti ⁴ , Sebastiano Foddai ⁵ , Armandodoriano Bianco ⁶ , Mauro Serafini ⁷

1 - Dipartimento di Biologia Ambientale, Università di Roma “La Sapienza”, Piazzale Aldo Moro, 5 – 00185 Rome, Italy
2 - Dipartimento di Chimica, Università di Roma “La Sapienza”, Piazzale Aldo Moro, 5 – 00185 Rome, Italy
3 - Dipartimento di Chimica, Università di Roma “La Sapienza”, Piazzale Aldo Moro, 5 – 00185 Rome, Italy
4 - Dipartimento di Chimica, Università di Roma “La Sapienza”, Piazzale Aldo Moro, 5 – 00185 Rome, Italy
5 - Dipartimento di Biologia Ambientale, Università di Roma “La Sapienza”, Piazzale Aldo Moro, 5 – 00185 Rome, Italy
6 - Dipartimento di Chimica, Università di Roma “La Sapienza”, Piazzale Aldo Moro, 5 – 00185 Rome, Italy
7 - Dipartimento di Biologia Ambientale, Università di Roma “La Sapienza”, Piazzale Aldo Moro, 5 – 00185 Rome, Italy

Received: 2017-05-29 Accepted : 2017-06-20 Published : 2017-06-01

Keywords: Phytochemistry, NMR spectroscopy, Chemotaxonomy, Ethnopharmacology, Abruzzo region, <i>Galeopsis ladanum</i> subsp. <i>angustifolia</i> (Ehrh. ex Hoffm.) Gaudin,

Abstract :

In this work, a phytochemical analysis on the total aerial parts of Galeopsis ladanum subsp. angustifolia (Ehrh. ex Hoffm.) Gaudin collected in Abruzzo region (Central Italy) has been reported. Nine compounds were identified belonging to five different classes of natural compounds. Additional chemotaxonomic markers were recognized than our previous study, as well. Their presence is perfectly in accordance with the current botanical classification of the species and shows the possibility of a pronounced metabolic variability. The observed phytochemical composition may also suggest the possible use of this species in the ethnopharmacological field just like most Galeopsis species since they are endowed with several medicinal properties. Furthermore, no potential toxic component was identified in the studied accession.

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