D-tartaric acid: a novel catalyst for green and efficient synthesis of 3,4-dihydropyrimidin-2(1H)-ones by Biginelli reaction under solvent-free conditions

Subject Areas :

Ali Ezabadi ¹ (Central Tehran Branch, Islamic Azad university, Sanat Square, Tehran, Iran)
Neda Ghassemi ² (Central Tehran Branch, Islamic Azad university, Sanat Square, Tehran, Iran)

Received: 2016-05-31 Accepted : 2016-05-31 Published : 2012-05-01

Keywords: Multicomponent reaction, Solvent-free conditions, 3, 4-Dihydropyrimidin-2(1H)-ones, D-tartaric acid, organo catalyst,

Abstract :

D-tartaric acid is successfully used as a green and efficient catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones under solvent-free conditions. The developed method has many advantages, including devoid of harmful catalyst and solvents, high yield and easily work-up.

References:

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D-tartaric acid: a novel catalyst for green and efficient synthesis of 3,4-dihydropyrimidin-2(1H)-ones by Biginelli reaction under solvent-free conditions