Introduction: The important factors in the development of chronic diseases are obesity and overweight. The purpose of this study was to investigate the effect of eight weeks aerobic training on interleukin- 6, insulin resistance and glucose in overweight young girls. Methods: Twenty-one girls with an age range of 20-30 years were selected voluntarily and randomly divided into experimental (n = 11) and control (n = 10) groups. The aerobic exercise program lasted for 8 weeks, with a frequency of 3 sessions per week, with training sessions starting from 30 minutes in the first session and 50 minutes in the final session, and the intensity of 60-70% of the heart rate reserve. The blood sample was taken before beginning the main study program. The independent sample t-test, paired sample t- test and the Kolmogorov–Smirnov test were used to compare the pre-test and post-test information between the groups. Results: Eight weeks of aerobic exercise had no significant effect on body mass index (p=0.43), fat percent (p=0.72), waist to hip rate (p=0.85), interleukin- 6 (p=0.86), insulin resistance (p=0.59) and glucose (p=0.78) nevertheless significantly reduced the weight (p=0.004). Conclusion: It appears that eight-week aerobic exercise program could be beneficial for weight loss, but it did not affect glucose concentration, insulin resistance, interleukin- 6 serum, fat percentage, waist to hip ratio and BMI. پرونده مقاله

Introduction: A number of studies have reported that regular aerobic exercises can improve cardiovascular biomarkers such as homocysteine, C- reactive protein and lipid profile. The purpose of this study was to investigate the effect of 4 weeks of aerobic exercise on homocysteine, C- reactive protein and lipid profile in active and inactive men. Methods: in this quasi-experimental study, 26 active (n = 13) and inactive (n = 13) students aged (18- 23) years old participated voluntarily. All subject performed aerobic exercises for 4 weeks, 3 sessions per week and 60 minutes with intensity of 60- 75 % of maximum heart rate reserve per session. Blood sample was taken in the pretest and 24 hours after the last aerobic exercise session in the post- test. Independent sample t- test and paired sample t- test were used to analyze the data (p≤0.05). Results: Serum levels of homocysteine (P = 0.001) and low density lipoprotein cholesterol to high density lipoprotein cholesterol (P = 0.003) significantly decreased in the active group compared to the inactive group. However, there were no significant difference in the changes of C-reactive protein (P = 0.12), low density lipoprotein cholesterol (P = 0.56), triglyceride (P = 0.24), total cholesterol (P = 0.21), total cholesterol to high density lipoprotein (P = 0.52) and triglyceride to high density lipoprotein (P = 0.26), between active and inactive group. Conclusion: It appears that serum levels of homocysteine reduced further after four weeks of exercise in active subjects in comparison with inactive subjects. However, the improvement in the serum levels of C-reactive protein and lipid profiles after four weeks of exercise training were the same in both active and inactive individuals. پرونده مقاله