Torsion of elastic and poroelastic circular shaft of radially inhomogeneous, cylindrically orthotropic materials is studied with emphasis on the end effects example for extruder. To examine the conjecture of Saint-Venant’s torsion, we consider torsion of circular shaft with one end fixed and the other end free on which tractions that results in a pure torque are prescribed arbitrarily over the free end surface. Exact solutions that satisfy the prescribed boundary conditions point by point over the entire boundary surfaces are derived in a unified manner for cylindrically orthotropic shafts with or without radial inhomogeneity and for their coun- terparts of Saint-Venant’s torsion. Stress diffusion due to the end effect is examined in the light of the exact solutions.The present study enables us to assess Saint-Venant’s principle as applied to anisotropic, non-homogeneous poroelastic bodies in general and to evaluate the stress diffusion in torsion of radially inhomogeneous, cylindrically orthotropic cylinders in particular. The following conclusions can be drawn from the analysis. پرونده مقاله

Torsion of elastic and poroelastic circular shaft of radially inhomogeneous, cylindrically orthotropic materials is studied with emphasis on the end effects example for extruder. To examine the conjecture of Saint-Venant’s torsion, we consider torsion of circular shaft with one end fixed and the other end free on which tractions that results in a pure torque are prescribed arbitrarily over the free end surface. Exact solutions that satisfy the prescribed boundary conditions point by point over the entire boundary surfaces are derived in a unified manner for cylindrically orthotropic shafts with or without radial inhomogeneity and for their coun- terparts of Saint-Venant’s torsion. Stress diffusion due to the end effect is examined in the light of the exact solutions.The present study enables us to assess Saint-Venant’s principle as applied to anisotropic, non-homogeneous poroelastic bodies in general and to evaluate the stress diffusion in torsion of radially inhomogeneous, cylindrically orthotropic cylinders in particular. The following conclusions can be drawn from the analysis پرونده مقاله

The drug making resreach has accentuated on extrusion technology for a long time. The advance of drug bioavailibility, bead manufacturing and granulation is assured by extrusion procedures. There are also diverse effects in resereches with respect to the use of process understanging as a tool in quality management. Many initiatives of FDA such as PAT and QBD are getting accepted. In this survey a corotating twin-screw extruder was facilitated with a torque gauge as a tool to monitor the process. The experimental arrangements were qualified based on the ICH instructions. The extrusion torque has a relation with the water content in a wet extrusion process. Besides, a process of pelletisation was done utilizing various formulations in wet spheronization. There found the relationship between the torque on the screws and the form of the pellet. In a nutshell, the torque proved to be a very good extrusion criteria for monitoring processes of wet extrusion پرونده مقاله