D-tartaric acid: a novel catalyst for green and efficient synthesis of 3,4-dihydropyrimidin-2(1H)-ones by Biginelli reaction under solvent-free conditions
محورهای موضوعی : Journal of Chemical Reactivity and SynthesisAli Ezabadi 1 , Neda Ghassemi 2
1 - Central Tehran Branch, Islamic Azad university, Sanat Square, Tehran, Iran
2 - Central Tehran Branch, Islamic Azad university, Sanat Square, Tehran, Iran
کلید واژه: Multicomponent reaction, Solvent-free conditions, 3, 4-Dihydropyrimidin-2(1H)-ones, D-tartaric acid, organo catalyst,
چکیده مقاله :
D-tartaric acid is successfully used as a green and efficient catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones under solvent-free conditions. The developed method has many advantages, including devoid of harmful catalyst and solvents, high yield and easily work-up.