D-tartaric acid: a novel catalyst for green and efficient synthesis of 3,4-dihydropyrimidin-2(1H)-ones by Biginelli reaction under solvent-free conditions
الموضوعات : International Journal of Heterocyclic Chemistry
Ali Ezabadi
1
(Central Tehran Branch, Islamic Azad university, Sanat Square, Tehran, Iran)
Neda Ghassemi
2
(Central Tehran Branch, Islamic Azad university, Sanat Square, Tehran, Iran)
الکلمات المفتاحية: Multicomponent reaction, Solvent-free conditions, 3, 4-Dihydropyrimidin-2(1H)-ones, D-tartaric acid, organo catalyst,
ملخص المقالة :
D-tartaric acid is successfully used as a green and efficient catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones under solvent-free conditions. The developed method has many advantages, including devoid of harmful catalyst and solvents, high yield and easily work-up.