Siparuna Aublet genus (Siparunaceae): from folk medicine to chemical composition and biological activity
محورهای موضوعی : Phytochemistry: Isolation, Purification, Characterization
Ingrede Silva
1
(Departamento de Ciências Exatas e Tecnológicas, Universidade Estadual de Santa Cruz, Ilhéus, Bahia, Brazil, 45662-900)
Fernando Oliveira
2
(Departamento de Ciências Exatas e Tecnológicas, Universidade Estadual de Santa Cruz, Ilhéus, Bahia, Brazil, 45662-900)
Rosilene Oliveira
3
(Departamento de Ciências Exatas e Tecnológicas, Universidade Estadual de Santa Cruz, Ilhéus, Bahia, Brazil, 45662-900)
کلید واژه: Antioxidant, Essential oils, Secondary metabolites, Antibacterial, Phytochemistry, Pharmacological activities,
چکیده مقاله :
Species of the genus Siparuna Aublet are found in Neotropical regions, mainly in the Andes. In the Brazilian folk medicine, some Siparuna species are used to combat fever, inflammation, pain, and infections. This paper presents a review of phytochemical studies and biological activities of species of this genus. Phytochemical studies of 18 species led to the isolation of mainly flavonoids (quercetin and kaempferol derivatives) as well as alkaloids (aporphinic derivatives). Essential oils were reported for 8 species among which S. guianensis is the most studied species. Numerous reports provide evidence of antimicrobial, antiplasmodic, larvicidal, cytotoxic, and antioxidant activities for some species of Siparuna genus. The reports of phytochemical studies and biological activities motivate the continued research of other species of the genus, remembering that a large part of the identified species are unknown from the natural products chemistry point of view.
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