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  • Occurrence of Zearalenone and Ochratoxin A in Cereals and Cereal Based Products

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کد مقاله : JCHR-547 بازدید : 149 صفحه: 0 - 0

10.22034/jchr.2015.544120

نوع مقاله: پژوهشی

Occurrence of Zearalenone and Ochratoxin A in Cereals and Cereal Based Products

محورهای موضوعی :

Reza Kazemi Darsanaki 1 , Saeid Rahbar 2 , Ahmad Tajehmiri 3

1 - Young Researchers and Elites Club, Lahijan Branch, Islamic Azad University, Lahijan, Iran
2 - Department of Microbiology, Lahijan Branch, Islamic Azad University, Lahijan, Iran
3 - Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran Razi Fara Teb Biotechnology Complex, Bistoon Industrial Zone, Kermanshah, Iran

تاریخ دریافت : 1394/06/24 تاریخ پذیرش : 1397/08/07 تاریخ انتشار : 1394/06/24

کلید واژه: Mycotoxin, Ochratoxin A, Zearalenone, cereals,

چکیده مقاله :

The contamination of cereals with toxic secondary metabolites of fungi, mycotoxins, is a permanent challenge in human health. These toxins are produced by a few fungi are mainly of the genera Fusarium, Aspergillus and Penicillium. Ochratoxin A is a nephrotoxic mycotoxin, which possesses carcinogenic, teratogenic, immunotoxic and possibly neurotoxic properties. Zearalenone is a non-steroidal estrogenic toxin, which has been involved in incidents of precocious pubertal changes. In this study, we reviewed recent researches in zearalenone and ochratoxin A contamination in cereals and cereal based products

چکیده انگلیسی:

منابع و مأخذ:
  1. Kazemi Darsanaki R., Issazadeh Kh., Azizollahi Aliabadi M., Mohammad Doost Chakoosari M., 2015. Occurrence of Deoxynivalenol (DON) in wheat flours in
  3. Guilan Province, northern Iran. Ann Agr Environ Med. 22(1), 35ââ‚‌“37.
  4. Ibáñez-Vea M., Martínez R., González-Peñas E., Lizarraga E., de Cerain A.L., 2011. Co-occurrence of aflatoxins, ochratoxin A and zearalenone in breakfast
  5. cereals from Spanish market. Food Control. 22(12), 1949-1955.
  6. Polisenska I., Pfohl-Leszkowicz A., Hadjeba K., Dohnal V., Jirsa O., Denesova O., Macharackova P., 2010. Occurrence of ochratoxin A and citrinin in Czech cereals and comparison of two HPLC methods for ochratoxin A detection. Food Addit Contam. 27(11), 1545-1557.
  7. Kuzdraliński A., Solarska E., Muszyńska M., 2013. Deoxynivalenol and zearalenone occurence in beers analysed by an enzyme-linked immunosorbent assay method. Food Control. 29(1), 22-24.
  8. Yazar S., Omurtag G.Z., (2008). Fumonisins, Trichothecenes and Zearalenone in Cereals. Int J Mol Sci. 9, 2062-2090.
  9. Zinedine A., Soriano J.M., Molto J.C., Manes J., 2007. Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: an oestrogenic mycotoxin. Food Chem Toxicol. 45(1), 1-18.
  10. Maragos C., 2010. Zearalenone occurrence and human exposure. World Mycotoxin J. 3(4), 369-383.
  11. Ahamed S., Foster J.S., Bukovsky A., Wimalasena J., 2001. Signal transduction through the ras/Erk pathway is essential for the mycoestrogen zearalenone-induced cell-cycle progression in MCF-7 cells. Mol Carcinog. 30, 88ââ‚‌“98.
  12. Food and Agriculture Organization (FAO), 2004. Worldwide regulations for mycotoxins in food and feed. Rome. 81.
  13. Kim J.C., Kang H., Lee D.H., Lee Y., Yoshizawa T., 1993. Natural occurrence of Fusarium mycotoxins (trichothecenes and zearalenone) in barley and corn in Korea. Appl Environ Microbiol. 59(11), 3798-3802.
  14. Li F.Q., Li Y.W., Luo X.Y., Yoshizawa T., 2002. Fusarium toxins in wheat from an area in Henan Province, PR China, with a previous human red mould intoxication episode. Food Addit Contam. 19(2), 163-167.
  15. Hadiani M.R., Yazdanpanah H., Ghazi Khansari M., Cheraghali A.M., Goodarzi M., 2003. Survey of the natural occurrence of zearalenone in maize from northern Iran by thin-layer chromatography densitometry. Food Addit Contam. 20, 380-385.
  16. Hedayati M., 2005. A Survey on wheat samples for mycotoxin zearalenone from Mazandaran Province 2002. J Mazandaran Univ Med Sci. 15(49), 89-94.
  17. Park J.W., Choi S.Y., Hwang H.J., Kim Y.B. 2005. Fungal mycoflora and mycotoxins in Korean polished rice destined for humans. Int J Food Microbiol. 103(3), 305-314.
  18. Abdulkadar A., Al-Ali A.A., Al-Kildi A.M., Al-Jedah J.H., 2004. Mycotoxins in food products available in Qatar. Food Control. 15(7), 543-548.
  19. Karami-Osboo R., Mirabolfathy M., 2008. Natural zearalenone contamination of wheat from golestan province, northern Iran. Iran J Plant Path. 44, 60-65.
  20. Oveisi M., Hajimahmoodi M., Memarian S., Sadeghi N., Shoeibi S., 2005. Determination of zearalenone in corn flour and a cheese snack product using high performance liquid chromatography with fluorescence detection. Food Addit Contam. 22, 443-448.
  21. Nuryono N., Noviandi C., Böhm J., Razzazi-Fazeli E., 2005. A limited survey of zearalenone in Indonesian maize-based food and feed by ELISA and high performance liquid chromatography. Food Control. 16(1), 65-71.
  22. Alkadri D., Rubert J., Prodi A., Pisi A., Mañes J., Soler C., 2014. Natural cooccurrence of mycotoxins in wheat grains from Italy and Syria. Food Chem. 157, 111-118.
  23. Rashedi M., Sohrabi H.R., Ashjaazadeh M.A., Azizi H., Rahimi E., 2012. Zearalenone contamination in barley, corn, silage and wheat bran. Toxicol Indus Health. 28(9), 779-782.
  24. Eftekhari M., Ahmadi A., Khezri H., Hassanzadeh J., 2015. The prevalence of weight ââ‚‌“ controlling attitude and eating disorders and their association with anthropometric indices in female adolescent students. Yafteh. 16 (3), 78-84.
  25. Yazdanpanah H., Zarghi A., Shafaati A.R., Foroutan S.M., Aboul-Fathi F., Khoddam A., Nazari F., 2012. Exposure Assessment of the Tehran Population (Iran) to Zearalenone Mycotoxin. Iranian journal of pharmaceutical research. IJPR. 11(1), 251.
  26. Liao C.D., Lin H.Y., Chiueh L.C., Shih D.Y.C., 2011. Simultaneous quantification of aflatoxins, ochratoxin A and zearalenone in cereals by LC-MS/MS. J Food Drug Anal. 19(3), 259-268.
  27. Iqbal S.Z., Rabbani T., Asi M.R., Jinap S., 2014. Assessment of aflatoxins, ochratoxin A and zearalenone in breakfast cereals. Food Chem.157, 257-262.
  28. Sadeghi E., Hashemian A.H., Bohlouli S., Mohammadi A., Yahya P., 2014. Evaluation of Zearalenone levels in Breads in Kermanshah city in 2012- 2013. Intl J Agri Crop Sci. 7(13), 1293-1297.
  29. Zinedine A., Brera C., Elakhdari S., Catano C., Debegnach F., Angelini S., Minardi V., 2006. Natural occurrence of mycotoxins in cereals and spices commercialized in Morocco. Food Control. 17(11), 868-874.
  30. El-Desouky T., Naguib K., 2013. Occurrence of zearalenone contamination in some cereals in Egypt. J Agro Processes Technol. 19(4), 445-450.
  31. Vrabcheva T., Geßler R., Usleber E., Märtlbauer E., 1996. First survey on the natural occurrence of Fusarium mycotoxins in Bulgarian wheat. Mycopathologia. 136(1), 47-52.
  32. Garaleviciene D., Pettersson H., Agnedal M., 2002. Occurrence of trichothecenes, zearalenone and ochratoxin A in cereals and mixed feed from central Lithuania. Mycotoxin Res. 18(2), 77-89.
  33. Schollenberger M., Müller H.M., Rüfle M., Suchy S., Plank S., Drochner W., 2006. Natural occurrence of 16 Fusarium toxins in grains and feedstuffs of plant origin from Germany. Mycopathologia. 161(1), 43-52.
  34. Domijan A., Peraica M., Cvjetković B., Turčin S., Jurjević Ž., Ivić D., 2005. Mould contamination and co-occurrence of mycotoxins in maize grain in Croatia. Acta Pharmaceutica. 55(4), 349-356.
  35. Mankevičienė A., Gaurilčikienė I., Dabkevičius Z., Semaškienė R., Mačkinaitė R., Supronienė S., 2006. Mycotoxin contamination of Lithuanian-grown cereal grains and factors determining it. Ekologija. 3, 21-27.
  36. Valcheva A., Valchev G., 2007. The fusariotoxins zearalenon and deoxinivalenol as natural contaminators of some basic cereal components in the production of combined feed. Bulgarian J Agri Sci. 13(1), 99-104.
  37. Jaimez J., Fente C.A., Franco C.M., Cepeda A., Vázquez B.I., 2004. A survey of the fungal contamination and presence of ochratoxin A and zearalenone on Spanish feed and raw materials. J Sci Food Agri. 84(8), 832-840.
  38. Scudamore K.A., Patel S., 2009. Occurrence of Fusarium mycotoxins in maize imported into the UK, 2004ââ‚‌“2007. Food Addi Contam. 26(3), 363-371.
  39. Šegvić Klarić M., Cvetnić Z., Pepeljnjak S., Kosalec I., 2009. Co-occurrence of aflatoxins, ochratoxin A, fumonisins, and zearalenone in cereals and feed, determined by competitive direct enzyme-linked immunosorbent assay and thin-layer chromatography. Arhiv za higijenu rada i toksikologiju. 60(4), 427-433.
  40. Cerveró M.C., Castillo M., Montes R., Hernández E., 2007. Determination of trichothecenes, zearalenone and zearalenols in commercially available corn-based foods in Spain. Revista Iberoamericana De Micología. 24(1), 52-55.
  41. Manova R., Mladenova R., 2009. Incidence of zearalenone and fumonisins in Bulgarian cereal production. Food Control. 20(4), 362-365.
  42. Marques M., Martins H., Costa J., Bernardo F., 2008. Co-occurrence of deoxynivalenol and zearalenone in crops marketed in Portugal. Food Addit Contam. 1(2), 130-133.
  43. Galbenu P., Damiescu L., Trif A., 2011. Zearalenone occurrence in cereal and cereal-based foodstuffs marketed in Timis County. Res J Agric Sci. 43, 43-49.
  44. Macri A., Miclăuş V., Dancea Z., Morar M.V., Paşca I., Scurtu I., Rus V., 2009. Zearalenone and trichothecene content of maize and wheat samples coming from center and western Romania. Analele Societatii Nationale de Biologie Celulara. 14(2), 315-318.
  45. Solarska E., Marzec M., Kuzdraliński A., Muszyńska M., 2012. The occurrence of mycotoxins in organic spelt products. J Plant Protect Res. 52(2), 190-195.
  46. Alexa E., Dehelean C.A., Poiana M.A., Radulov I., Cimpean A.M., Bordean D.M., Pop G., 2013. The occurrence of mycotoxins in wheat from western Romania and histopathological impact as effect of feed intake. Chem Central J. 7(1), 99.
  47. Pleadin J., Vahčić N., Perši N., Ševelj D., Markov K., Frece J., 2013. Fusarium mycotoxins' occurrence in cereals harvested from Croatian fields. Food Control. 32(1), 49-54.
  48. Škrbić B., Živančev J., Đurišić-Mladenović N., Godula M., 2012. Principal mycotoxins in wheat flour from the Serbian market: Levels and assessment of the exposure by wheat-based products. Food Control. 25(1), 389-396.
  49. Aldana J.R., Silva L.J., Pena A., Mañes J., Lino C.M., 2014. Occurrence and risk assessment of zearalenone in flours from Portuguese and Dutch markets. Food Control. 45, 51-55.
  50. Silva C.M.G., Vargas E.A., 2001. A survey of zearalenone in corn using Romer Mycosepâ„¢ 224 column and high performance liquid chromatography. Food Addit Contam. 18 (1), 39- 45.
  51. Sekiyama B.L., Ribeiro A.B., Machinski P.A., Machinski Junior M., 2005. Aflatoxins, ochratoxin A and zearalenone in maize-based food products. Br J Microbiol. 36(3), 289-294.
  52. Almeida-Ferreira G.C., Barbosa-Tessmann I.P., Sega R., Machinski Junior M. 2013. Occurrence of zearalenone in wheat-and corn-based products commercialized in the State of Paraná, Brazil. Br J Microbiol. 44(2), 371-375.
  53. Azizi I.G., Rahimi K., Shateri S., 2012. Ochratoxin: contamination and toxicity (a review). Glob. Veterinaria. 8, 519-524.
  54. Kabak B., 2009. Ochratoxin A in cereal-derived products in Turkey: occurrence and exposure assessment. Food and Chem Toxicol. 47(2), 348-352.
  55. Kumar R., Ansari K.M., Saxena N., Dwivedi P.D., Jain S.K., Das M., 2012. Detection of ochratoxin A in wheat samples in different regions of India. Food Control. 26(1), 63-67.
  56. Lin L.C., Chen P.C., Fu Y.M., Shih D.Y.C., 2005. Ochratoxin A contamination in coffees, cereals, red wines and beers in Taiwan. J Food Drug Anal. 13(1), 84-92.
  57. Trung T., Bailly J., Querin A., Le Bars P., Guerre P., 2001. Fungal contamination of rice from South Vietnam, mycotoxinogenesis of selected strains and residues in rice. Revue de Médecine Vétérinaire. 152(7), 555-560.
  58. Kumagai S., Nakajima M., Tabata S., Ishikuro E., Tanaka T., Norizuki H., Kai S., 2008. Aflatoxin and ochratoxin a contamination of retail foods and intake of these mycotoxins in Japan. Food Addit Contamin. 25(9), 1101-1106.
  59. Nguyen M.T., Tozlovanu M., Tran T.L., Pfohl-Leszkowicz A., 2007. Occurrence of aflatoxin B1, citrinin and ochratoxin a in rice in five provinces of the central region of Vietnam. Food chemistry. 105(1), 42-47.
  60. Hadian Z., Yazdanpanah H., Azizi M., Seyed A.F., Koushki M., Hosseini P.S., Mortezaei G.R., Shojaei A.F., Khoshgozaran S., 2009. Occurrence of ochratoxin A in rice sold in chain stores in Tehran, 2007. Iran J Nutr Sci Food Technol. 4(2), 53-59.
  61. Mahtabani A., Bayat M., Hosseini S.E., Aminafshar M., Tavakoli H., 2011. Assessment of Ochratoxin A and Aflatoxin B1, B2, G1, G2 Rates in Breakfast Grains of Supermarkets in Tehran Using HPLC Method in 2010. Hakim. 14(1), 10-15.
  62. Rahimi E., Erfani M., Shakerian A., 2014. Frequency of ochratoxin A in bread consumed in Shahrekord. J Shahrekord Univ Med Sci. 16(2), 63-69.
  63. Ayalew A., Fehrmann H., Lepschy J., Beck R., Abate D., 2006. Natural occurrence of mycotoxins in staple cereals from Ethiopia. Mycopathologia. 162(1), 57-63.
  64. Hajjaji A., El Otmani M., Bouya D., Bouseta A., Mathieu F., Collin S., Lebrihi A., 2006. Occurrence of mycotoxins (ochratoxin a, deoxynivalenol) and toxigenic fungi in Moroccan wheat grains: impact of ecological factors on the growth and ochratoxin a production. Mol Nutr Food Res. 50(6), 494-499.
  65. Zaied C., Abid S., Zorgui L., Bouaziz C., Chouchane S., Jomaa M., Bacha H., 2009. Natural occurrence of ochratoxin A in Tunisian cereals. Food Control. 20(3), 218-222.
  66. Dongo L., Manjula K., Orisajo S., 2007. Occurrence of ochratoxin A in Nigerian kola nuts. African Crop Science Conference Proceedings. 8, 2133-2135.
  67. Gwary O.M., Hati S.S., Dimari G.A., Ameh, J.A., 2012. Assessment of Mycotoxins (Total Aflatoxins and Ochratoxin-A) Contamination of Staple Cereals. IJCBS. 2, 1-6.
  68. Palermo D., Pietrobono P., Palermo C., Rotunno T., 2002. Occurrence of Ochratoxin A in cereals from Puglia (Italy). Italian J Food Sci. 14(4), 447-453.
  69. Fazekas B., Tar A., Zomborszky-Kovacs M., 2002. Ochratoxin A contamination of cereal grains and coffee in Hungary in the year 2001. Acta Veterinaria Hungarica. 50(2), 177-188.
  70. Pena A., Cerejo F., Lin C., Silveira I., 2005. Determination of ochratoxin A in Portuguese rice samples by high performance liquid chromatography with fluorescence detection. Anal Bioanal Chem. 382(5), 1288-1293.
  71. Molinié A., Faucet V., Castegnaro M., Pfohl-Leszkowicz A., 2005. Analysis of some breakfast cereals on the French market for their contents of ochratoxin A, citrinin and fumonisin B 1: development of a method for simultaneous extraction of ochratoxin A and citrinin. Food Chem. 92(3), 391-400.
  72. Juan C., Moltó J., Lino C., Mañes J., 2008. Determination of ochratoxin A in organic and non-organic cereals and cereal products from Spain and Portugal. Food Chem. 107(1), 525-530.
  73. Araguás C., González-Peñas E., De Cerain A.L., 2005. Study on ochratoxin A in cereal-derived products from Spain. Food Chem. 92(3), 459-464.
  74. Cengiz M., Oruç H.H., Uzunoglu I., Sonal S. 2007. Ochratoxin A levels in different types of bread and flour. Uludag Univ J Fac Vet Med. 26, 7-10.
  75. González-Osnaya L., Soriano J., Moltó J., Mañes J., 2007. Dietary intake of ochratoxin A from conventional and organic bread. International Journal of Food Microbiology. 118(1), 87-91.
  76. Villa P., Markaki P., 2009. Aflatoxin B1 and ochratoxin A in breakfast cereals from Athens market: occurrence and risk assessment. Food Control. 20(5), 455-461.
  77. Duarte S., Bento J., Pena A., Lino C., 2009. Ochratoxin A exposure assessment of the inhabitants of Lisbon during winter 2007/2008 through bread and urine analysis. Food Addit Contam. 26(10), 1411-1420.
  78. Vega M., Muñoz K., Sepúlveda C., Aranda M., Campos V., Villegas R., Villarroel O., 2009. Solid-phase extraction and HPLC determination of Ochratoxin A in cereals products on Chilean market. Food Control. 20(7), 631-634.

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