Aflatoxin M1 Contamination in Milk and Milk Products in Iran: A Review

محورهای موضوعی :

R. Kazemi Darsanaki ¹ ( Department of Microbiology, Faculty of Science, Lahijan Branch, Islamic Azad University, Lahijan, Iran )
M. Mohammad Doost Chakoosari ² ( Department of Microbiology, Faculty of Science, Lahijan Branch, Islamic Azad University, Lahijan, Iran )
M. Azizollahi Aliabadi ³ ( Department of Microbiology, Faculty of Science, Lahijan Branch, Islamic Azad University, Lahijan, Iran )

تاریخ دریافت : 1392/09/16 تاریخ پذیرش : 1397/08/07 تاریخ انتشار : 1392/06/10

کلید واژه: Iran, Milk, Aflatoxin M1, Milk products,

چکیده مقاله :

Mycotoxins are secondary metabolites of molds and have adverse effects on humans, animals, and crops. Those can cause illnesses and economic losses. Aflatoxin M1 (AFM1) is one of the mycotoxins produced from the hydroxylated metabolite of aflatoxin B1 (AFB1). It can be found in milk or milk products obtained from livestock that have ingested contaminated feed. In this paper, recent studies were reviewed in aflatoxin M1 contamination in milk and milk products in Iran.

منابع و مأخذ:

1. Tabari M., Tabari K., Tabari O. Occurrence of
2. Aflatoxin M1 in Pasteurized Doogh
3. Commercialized in Tehran, Iran. Australian
4. Journal of Basic and Applied Sciences, 2011.
5. (12): 1734-1737.
6. Tajkarimi M., Aliabadi-Sh F., Salah Nejad A.,
7. Poursoltani H., Motallebi A.A., Mahdavi H.,
8. Aflatoxin M1 contamination in winter and summer
9. milk in 14 states in Iran. Food Control, 2008.19:
10. -1036.
11. Nilchian Z., Rahimi E., Aflatoxin M1 in
12. Yoghurts, Cheese and Ice-Cream in Shahrekord-
13. Iran. World Applied Sciences Journal, 2012. 19
14. (5): 621-624.
15. Khlangwiset P., Shephard G.S., Wu F.,
16. Aflatoxins and growth impairment: A review.
17. Critical Reviews in Toxicol, 2011. 41: 1-16.
18. Azizollahi Aliabadi M., Issazadeh K., Kazemi
19. Darsanaki R., Laleh Rokhi M., Amini A.
20. ,Determination of Aflatoxin M 1Levels in White
21. Cheese Samples by ELISA in Gilan Province,
22. Iran. Global Veterinaria, 2012. 8 (7): 707-710.
23. Celik T.H., Sarımehmetoglu B., Kuplulu O.,
24. Aflatoxin M1 contamination in pasteurised milk.
25. Veterinarski Arhiv, 2005.75: 57-65.
26. Akkaya L., Birdane Y.O., Oguz H., Cemek M.,
27. Occurrence of aflatoxin M1 in yogurt samples from
28. afyonkarahisar, Turkey. Bull Vet Inst Pulawy,
29. 50: 517-519.
30. European Commission (EC), No 1881/2006 of
31. December 2006 setting maximum levels for
32. certain contaminants in foodstuffs. Off J Eur
33. Union, 2006. 364; 5-24.
34. Ghiasian S.A., Maghsood A.H., Neyestani T.R.,
35. Mirhendi S.H., Occurrence of aflatoxin M1 in raw
36. milk during the summer and winter seasons in
37. Hamedan, Iran. Journal of Food Safety, 2007. 27:
38. ââ‚‌“198.
39. Alborzi S., Pourabbas B., Rashidi M., Astaneh
40. B., Aflatoxin M1 contamination in pasteurized
41. milk in Shiraz (south of Iran). Food Control,
42. 17(7): 582-584.
43. Mokhtarian Dalouei H., Mohsenzadeh M.,
44. Evaluation of Aflatoxin M1 in Pasteurized Milk
45. Gonabad city. Ofogh-E-Danesh, 2005. 11(3): 5-9.
46. Gholampour Azizi I., Khoushnevis S.H.,
47. Hashemi S.J., Aflatoxin M1 level in pasteurized
48. and sterilized milk of Babol city. Tehran
49. University Medical Journal, 2007. 65: 20-24.
50. Nazari A., Noroozi H., Movahedi M.,
51. Khaksarian M., Measurement of Aflatoxin M1 in
52. Raw and Pasteurized.Yafte, 2007. 9(3): 49-57.
53. Tajik H., Razavi Rohani S.M., Moradi M.,
54. Detection of Aflatoxin M1 in Raw and
55. Commercial Pasteurized Milk in Urmia, Iran.
56. Pakistan Journal of Biological Sciences, 2007.10:
57. -4107.
58. Sefidgar S.A.A., Mirzae M., Assmar M.,
59. Naddaf S.R., Aflatoxin M1 in Pasteurized Milk in
60. Babol city, Mazandaran Province, Iran. Iranian J
61. Publ Health, 2011. 40:115-118.
62. Karimi G., Hassanzadeh M., Teimuri M.,
63. Nazari F., Nili A., Aflatoxin M1 Contamination in
65. Pasteurized Milk in Mashhad, Iran. Iranian Journal
66. of Pharmaceutical Sciences, 2007. 3(3): 153-156.
67. Sefidgar S.A., Azizi G., Khosravi A.R.,
68. Roudbar-Mohammadi S., Presence of Aflatoxin
69. M1 in raw Milk at Cattle Farms in Babol, Iran.
70. Pakistan Journal of Biological Sciences, 2008.
71. (3):484-486.
72. Mohammadian B., Khezri M., Ghasemipour
73. N., Mafakheri Sh., Poorghafour Langroudi P.,
74. Aflatoxin M1 contamination of raw and
75. pasteurized milk produced in Sanandaj, Iran.
76. Archives of Razi Institute, 2010. 65(2): 99-104.
77. Kamkar A., Detection of aflatoxin M1 in
78. powdered milk samples by ELISA. Pajouhesh &
79. Sazandegi, 2007. 79: 174-180.
80. Oveisi M.R., Jannat B., Sadeghi N.,
81. Hajimahmoodi M., Nikzad A., Presence of
82. aflatoxin M1 in milk and infant milk products in
83. Tehran, Iran. Food Control, 2007.18: 1216ââ‚‌“1218.
84. Movassagh M.H., Presence of aflatoxin in
85. UHT milk in Tabriz (Northwest of Iran). Journal
86. of Food Safety, 2011. 31(2): 238ââ‚‌“241.
87. Mohamadi Sani A., Nikpooyan H., Moshiri R.,
88. Aflatoxin M 1 contamination and antibiotic
89. residue in milk in Khorasan province, Iran. Food
90. and Chemical Toxicology, 2010. 48(8): 2130-
92. Riazipour M., Tavakkoli H.R., Razzaghi
93. Abyane M., Rafati H., Sadr Momtaz S.M.,
94. Measuring the amount of M1 Aflatoxin in
95. pasteurized milks. Kowsar Medical Journal, 2010.
96. (2): 89-93.
97. Fallah A.A., Aflatoxin M1 contamination in
98. dairy products marketed in Iran during winter and
99. summer. Food Control, 2010. 21: 1478-1481.
100. Movassagh M.H., Presence of Aflatoxin M1
101. Eweââ‚‌™s Milk in the Northwest Region of Iran.
102. Journal of Applied Biological Sciences, 2009.
103. (3):17-19.
104. Behfar A., Nazari Khorasgani Z., Alemzadeh
105. Z., Gudarzi M., Ebrahimi R., Tarhani N.,
106. Determination of Aflatoxin M1 Levels in
107. Produced Pasteurized Milk in Ahvaz City by
108. Using HPLC. Jundishapur J Nat Pharm Prod,
109. 7(2):80-84.
110. Behnamipour S., Arast Y., Mohammadian M.,
111. Occurence of aflatoxin M1 in two dairy products
112. by ELISA in central part of Iran. Life Science
113. Journal, 2012. 9(3): 1831-1833.
114. Fallah A., Assessment of aflatoxin M1
115. contamination in pasteurized and UHT milk
116. marketed in central part of Iran. Food and
117. Chemical Toxicology, Food Chem Toxicol, 2010.
118. (3): 988-991.
119. Daraei Garmakhany A., Zighamian H.,
120. Sarhangpour R., Rasti M., Aghajani N.,
121. Occurrence of Aflatoxin M1 in Raw and
122. pasteurized milk in Esfahan province of Iran.
123. Minerva Biotecnologica, 2011. 23: 53-7.
124. Kamkar A., Jahed Khaniki G.R., Alavi S.A.,
125. Occurrence of aflatoxin M1 in raw milk produced
126. in Ardebil of Iran. Iran. J. Environ. Health. Sci.
127. Eng, 2011. 8(2): 123-128.
128. Kamkar A., The study of aflatoxin M1 in UHT
129. milk samples by ELISA. J.Vet.Res, 2008. 63(2): 7-
131. Sadeghi E., Almasi A., Bohloli-Oskoii S.,
132. Mohamadi M., The Evaluation of Aflatoxin
133. M1Level in Collected Raw Milk for Pasteurized
134. Dairy. Zahedan J Res Med Sci, 2013. 15(3): 26-29.
135. Rahimi E., Nilchian Z., Behzadnia A.,
136. Presence of Aflatoxin M1 in Pasteurized and UHT
137. Milk Commercialized in Shiraz, Khuzestan and
138. Yazd, Iran. Journal of Chemical Health Risks,
139. 1(1): 7-10.
140. Panahi P., Kasaee S., Mokhtari A., Sharifi A.,
141. Jangjou A., Assessment of Aflatoxin
142. M1Contamination in Raw Milk by ELISA in
143. Urmia, Iran. American-Eurasian Journal of
144. Toxicological Sciences, 2011. 3(4): 231-233.
146. Journal of Chemical Health Risks 3(3): 13-20, 2013
147. ISSN:2251-6719
148. Rahimi E., Mohammadhosseini M., Alimoradi
149. M., Rezaei P., Arab M., Goudarzi M.A., Tarkesh
150. Esfahani M., Torki Z., Aflatoxin M1 in
151. Pasteurized Milk and White Cheese in Ahvaz,
152. Iran. Global Veterinaria, 2012. 9(4): 384-387.
153. Mohamadi Sani A., Khezri M., Moradnia H.,
154. Determination of AflatoxinM1 in Milk by ELISA
155. Technique in Mashad (Northeast of Iran). ISRN
156. Toxicology, 2012.1-4.
157. Gholi pour M., Karim zadeh L., Ali Nia F.,
158. Babaee Z., Determination of Aflatoxin M1 in
159. Mazandaran Province at the First Half of 1390. J
160. Mazand Univ Med Sci, 2012. 22(93): 40-46.
161. Laleh rokhi M., Kazemi Darsanaki R.,
162. Mohammadi M., Hassani Kolavani M., Issazadeh
163. K., Azizollahi Aliabadi M., Determination of
164. Aflatoxin M1 Levels in Raw Milk Samples in
165. Gilan, Iran. Advanced Studies in Biology, 2013. 5:
166. -156.
167. Mohamadi Sani A., Nikpoyan H.,
168. Determination of aflatoxin M1 in milk by highperformance
169. liquid chromatography in Mashhad
170. (north east of Iran). Toxicol Ind Health, 2013.
171. (4): 334-338.
172. Fallah A.A., jafari T., Fallah A., Rahnama M.,
173. Determination of aflatoxin Ml levels in Iranian
174. white and cream cheese. Food and Chemical
175. Toxicology, 2009. 47: 1872-1875.
176. Rahimi E., Jafarian Dehkordi M., Iranpoor A.,
177. A Survey of Aflatoxin M1 Contamination in
178. Iranian White Cheese. Food Technology &
179. Nutrition, 2011. 8(4): 51-56.
180. Rahimi E., Mohammadhosseini M., Alimoradi
181. M., Rezaei P., Arab M., Goudarzi M.A., Tarkesh
182. Esfahani M., Torki Z., Aflatoxin M1 in
183. Pasteurized Milk and White Cheese in Ahvaz,
184. Iran. Global Veterinaria, 2012. 9(4): 384-387.
185. RahimiE., Survey of the occurrence of
186. aflatoxin M1 in dairy products marketed in Iran.
187. Toxicol Ind Health, 2012. doi:
188. 1177/0748233712462476.
189. Akrami Mohajeri F., Ghalebi S.R., Rezaeian
190. M., Gheisari H.R., Khorramdel Azad H.,
191. Zolfaghari A., Fallah A., Aflatoxin M1
192. contamination in white and Lighvan cheese
193. marketed in Rafsanjan, Iran. Food Control, 2013.
194. :525-527.
195. Barjesteh M.H., Gholampour I., Noshfar E.,
196. Occurrence of aflatoxin M1 in pasteurized and
197. local yogurt in mazandaran province (Northern of
198. Iran) using ELISA. Global Veterinaria, 2010. 4(5):
199. -462.
200. Issazadeh K., kazemi Darsanaki R., Majid
201. Khoshkholgh Pahlaviani M. R., Occurrence of
202. aflatoxin M1 levels in local yogurt samples in
203. Gilan Province, Iran. Annals of Biological
204. Research, 2012. 3 (8): 3853-3855.
205. Tabari M., Tabari K., Tabari O., Aflatoxin M1
206. determination in yoghurt produced in Guilan
207. province of Iran using immunoaffinity column and
208. high-performance liquid chromatography. Toxicol
209. Ind Health, 2013. 29(1):72-76.
210. Kazemi Darsanaki R., Azizollahi Aliabadi M.,
211. Mohammad Doost Chakoosari M., Aflatoxin M1
212. Contamination in Ice-Cream. Journal of Chemical
213. Health Risks, 2013. 3(1): 43-46.
214. Khosravi A., Shokri H., Eshghi S., Darvishi S.,
215. Global occurrence of aflatoxin M1 in milk with
216. particular reference to Iran, Food Security. 2013.
217. 1007/s12571-013-0281-9.
218. Davoudi Y., Garedaghi Y., Survey on
219. Contaminated Raw Milks with Aflatoxin M1 in
220. the Sarab Region, Iran. Research Journal of
221. Biological Sciences, 2011. 6: 89-91.
222. Vagef R., Mahmoudi R., Occurrence of
223. Aflatoxin M1 in raw and pasteurized milk
224. produced in west region of Iran (during summer
225. and winter). International Food Research Journal,
226. 20(3): 1421-1425.
227. Heshmati A., Occurrence of aflatoxin M1 in
228. Iranian white cheese. JFST, 2010. 7(2):117-122.
229. Hazhir M., Sanoubar Tahaiee N., Rashidi K.,
230. Rezaie R., Shaykhi H., Determination of the
231. amount of aflatoxin in milk samples delivered to
232. Sanandaj pasteurized Milk Corporation. SJKU,
233. ; 13(1): 44-50.
234. Rahimi E., Karim G., Determination of AFM1
235. in the Raw Milk Producing in Dairy Farms in
236. Chahar-Mahal-Bakhtiari Province Using ELISA.
237. JFST, 2008. 5(1): 51-58.
238. Afshar P., Shokrzadeh M., Kalhori S., Babaee
239. Z., Saeedi Saravi S.S., Occurrence of Ochratoxin
240. A and Aflatoxin M1 in human breast milk in Sari,
241. Iran. Food Control, 2013. 31: 525-529.
242. Kamkar A., Yazdankhah S., Mohammadi
243. Nafchi A., Mozaffari Nejad A., Aflatoxin M1 in
244. raw cow and buffalo milk in Shush city of Iran.
245. Food Additives & Contaminants: Part B, 2013.
246. doi:10.1080/19393210.2013.830277.
247. Tavakoli HR., Riazipour M., Rafati Shaldehi
248. H., Shahriari M., Naghavi S., Rahmati Najarkolaei
249. F., AFM1 Contamination in used yogurt in one
250. the of universities of medical sciences in Tehran
251. by ELISA. Quarterly of the Horizon of Medical
252. Sciences, 2013. 5S: 261-268