Possibilities for Improvement of Humoral Innate Immunity in Turkeys and Hens in Conditions of Thermal Stress by the Immunomodulator Immunobeta®
محورهای موضوعی : Camelن. بوزاکووا 1 , ل. سوتیرو 2 , س. دنو 3 , ت. کوینارسکی 4
1 - Department of Animal Hygiene, Ethology and Animal Protection, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria
2 - Department of Animal Genetics, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria
3 - Department of Biochemistry and Microbiology, Faculty of Agriculture, Trakia University, Stara Zagora, Bulgaria
4 - Department of Animal Genetics, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria
کلید واژه: lysozyme, beta-lysins, complement, hens, immunobeta, turkeys,
چکیده مقاله :
The experiments for evaluation of the effect of Immunobeta® were performed with turkeys and organically reared layer hens. Turkeys received Immunobeta® at a dose of 4 g/kg feed during the beginning of lay (cold period), thermoneutral period and hot summer period. In hens, two dietary levels of Immunobeta® were tested: 2 g/kg and 4 g/kg. Blood serum and egg white lysozyme levels, alternative pathway of complement activation (APCA) and beta-lysins concentrations were determined. It was found out that Immunobeta® had a beneficial effect on serum lysozyme, APCA activity and beta-lysins in turkeys and hens. The lysozyme concentration in egg white was significantly higher in eggs produced by birds treated with both doses of the immunomodulator. Immunobeta®, offered at a dose of 4.0 g/kg feed had a beneficial effect on natural humoral immunity factors. Applied at a dose of 4.0 g/kg, the tested immunomodulator increased significantly egg white lysozyme concentrations in hens, presuming a higher shelf life of eggs and possibly, better protection of chick embryos.
آزمایش‌هایی برای ارزیابی اثر Immunobeta با بوقلمون‌ها و مرغ‌های تخمگذار پرورشیافته ارگانیک انجام شد. بوقلمون‌ها Immunobeta را در یک دز چهار گرم/کیلوگرم خوراک در طول شروع تخمگذاری (دوره سرد)، دوره حرارتی خنثی و دوره گرم تابستان دریافت کردند. در مرغ‌ها، دو سطح جیره‌ای Immunobeta آزمون شدند: دو گرم/کیلوگرم و چهار گرم/کیلوگرم. سرم خون و سطوح لیزوزیم سفیده تخم مرغ، مسیر جایگزین فعالسازی مکمل (APCA) و غلظت‌های بتا-لایزین تعیین شدند. مشخص شد که Immunobeta تأثیر سودمندی بر لیزوزیم سرم، فعالیت APCA و بتا-لایزین در بوقلمون‌ها و مرغ‌ها داشت. غلظت لیزوزیم در سفیده تخم مرغ به طور معنی‌داری در تخم‌های تولید شده توسط پرندگان تیمار شده با هر دو دز تعدیلکننده سیستم ایمنی بالاتر بود. Immunobeta، پیشنهاد شده با یک دز چهار گرم/کیلوگرم خوراک تأثیر سودمندی روی فاکتورهای ایمنی طبیعی هومورال داشت. با اعمال یک دز چهار گرم/کیلوگرم، تعدیلکننده سیستم ایمنی تست شده به طور معنی‌داری غلظت‌های لیزوزیم سفیده تخم مرغ را در مرغ‌ها افزایش داد، با فرض ماندگاری بالاتر تخم‌ها و احتمالاً، محافظت بهتر از جنین جوجه‌ها.
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