List of Articles

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  1 - Physiological and antioxidant properties of marigold (Calendula officinalis L.) as influenced by methyl jasmonate and estradiol
  Shahram Sedaghat Hoor Fatemeh Raof Hagh Parvar
  Introduction: Marigold (Calendula officinalis L.) is an ornamental and medicinal plant from the family Asteraceae that is originated from the Mediterranean region, Western Asia, and Central Europe. The application of steroids to plants is an interesting subject. Steroid More

  Introduction: Marigold (Calendula officinalis L.) is an ornamental and medicinal plant from the family Asteraceae that is originated from the Mediterranean region, Western Asia, and Central Europe. The application of steroids to plants is an interesting subject. Steroid hormones, such as estradiol, stimulate growth and development and root and stem elongation. Mammalian sex hormones (progesterone, β-estradiol, and androsterone) stimulate antioxidant systems and enhance the growth of plants. Jasmonic acid and methyl jasmonate (MeJA) widely occur in plants and are involved in a wide range of processes, including fruit ripening, the production of viable and active pollens, root growth, tendril coiling, and protection against pathogens and insects. The present research aimed to investigate the effects of methyl jasmonate (MeJA) and estradiol on some physiological traits, including vegetative parameters and antioxidant properties of marigold.Experimental: The study carried out as a factorial experiment based on a Randomized Complete Block Design with two factors including MeJA at four rates (0, 10, 100 and 500 μM) and estradiol at four rates (0, 1, 5 and 10 mg/l) with 16 treatments, 3 replications, and 48 plots. The growth regulators were used as the foliar application at three phases in 2-week intervals. The recorded traits included leaf number, plant fresh and dry weight, anthocyanin, carotenoid, chlorophyll a, b and total, catalase activity, peroxidase enzyme, petal flavonoid, and antioxidant property.Results: The analysis of variance revealed that the simple effect of MeJA was significant on leaf number, antioxidant capacity, total chlorophyll, and petal carotenoid. Also, the simple effect of estradiol was significant on leaf number, plant dry weight, anthocyanin, peroxidase enzyme, and flavonoid. It was found that MeJA × estradiol was significant for leaf number, total chlorophyll, petal carotenoid, anthocyanin, catalase enzyme activity, peroxidase enzyme activity, antioxidant capacity, plant dry weight, and chlorophyll a and b content. The results showed that MeJA at the rate of 10 μM was most effective in the number of leaves and total chlorophyll. At the rate of 500 μM, it was also effective in the antioxidant capacity. Estradiol at the rate of 10 mg/l was the best treatment for dry weight, peroxidase activity, and flavonoid content. It was observed that 10 μM MeJA × 10 mg/l estradiol resulted in the highest leaf number and chlorophyll content and 500 μM MeJA × 10 mg/l estradiol was related to the highest chlorophyll b content and peroxidase enzyme activity. According to the results, it is recommended to apply estradiol and MeJA to improve the pigments and antioxidant capacity of Calendula officinalis. Dry weight and leaf number were increased with estradiol application. The results confirmed that the application of naturally occurring compounds, like MeJA and steroids, can increase secondary metabolites such as flavonoids and antioxidant enzymes and activity.Conclusion: To further learn about plant regulators in the future, it is recommended to examine the impact of MeJA and steroids on other plants under biotic and abiotic stresses. Extension: Based on the results, growers can apply estradiol and MeJA to improve the pigments and antioxidant capacity of Calendula officinalis. Manuscript profile
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  2 - Identification of some medicinal plants in Rustam region (Fars province, Iran)
  Saeideh Khaloei Elham Hatami
  Introduction: Medicinal plants are an important part of traditional medicine in many countries including Iran and they are also valuable in new therapeutic approaches. The aim of this study is to identify some medicinal plants that local residents of Rustam and surround More

  Introduction: Medicinal plants are an important part of traditional medicine in many countries including Iran and they are also valuable in new therapeutic approaches. The aim of this study is to identify some medicinal plants that local residents of Rustam and surrounding villages are widely used in treatment of disease.Experimental: The data sheets were recorded by using field surveys, knowledge of local people, identification and classification of these plants. For each species, scientific name, local name, usable organs of plants and common therapeutic properties were provided. The totals of 54 species belonging to 33 families were collected. Asteraceae with eight species was the largest families among the other families.Results: Most of these medicinal plants were used for treatment of gastrointestinal and infectious disease. A large number of plants in this region have medicinal properties and economic values. Therefore, it is essential for local people and natural resources organization to protect them against extinction and uncontrolled harvesting.Conclusion: The results of this study showed that these plants are mostly used in the treatment of gastrointestinal diseases. Manuscript profile
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  3 - Paper of Student: A review of thyme medicinal plant
  Hossein Raisi
  This article describes the characteristics of the thyme plant in general. Thyme is one of the oldest medicinal plants and spices. Today, this medicinal plant is used to treat many diseases such as colds, sore throats, headaches, muscle cramps, excretion of intestinal pa More

  This article describes the characteristics of the thyme plant in general. Thyme is one of the oldest medicinal plants and spices. Today, this medicinal plant is used to treat many diseases such as colds, sore throats, headaches, muscle cramps, excretion of intestinal parasites, severe coughs, bronchitis, sore throats, gum infections, etc. Thyme leaf is used in food products as well as its essential oil in beverages and pharmaceutical, health and cosmetics industries. Thyme oil has antispasmodic, windbreak, antifungal, antioxidant, antibacterial, disinfectant, anthelmintic, and expectorant, natural food preservative and anti-aging properties for mammals. Thyme essential oil is one of the ten famous essential oils that have a special place in world trade. There is a lot of research on thyme, and every day with the advancement of science, new cases of the properties of this plant for the treatment of patients with various diseases are found, which is certainly commendable. Manuscript profile
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  4 - Variation on biological activities and total phenol and flavonoids contents in different extracts from Salvia rhytidea Bent. collected from natural habitats of Kerman and Sistan and Baluchestan provinces
  Omid Azizian-Shermeh Alireza Hassanabadi
  Introduction: The variety of quantity and quality of active ingredients as well as the antioxidant function of medicinal plants under different ecological conditions has made plants as a valuable and natural source of new antioxidants in the focus of researchers. Salvia More

  Introduction: The variety of quantity and quality of active ingredients as well as the antioxidant function of medicinal plants under different ecological conditions has made plants as a valuable and natural source of new antioxidants in the focus of researchers. Salvia rhytidea Bent is one of the native medicinal plants of Sistan and Baluchestan and Kerman provinces. The genus Salvia belongs to the genus Lamiaceae, with more than 311 species worldwide, especially in tropical and temperate regions. The present study is carried out to evaluate the phytochemical compounds such as total phenolic and total flavonoid contents, antioxidant and antibacterial activities of three extracts (Methanolic, Ethanolic and Aqueous) of Salvia rhytidea Bent from natural habitats of Kerman and Sistan and Baluchestan province.Experimental:  Phenolic and Flavonoid contents were determined by Folin-Ciocaltiu, Aluminum Chloride colorimetric and antioxidant activities were studied by two methods (DPPH and FRAP) and antimicrobial activities were estimated by Disk-Diffusion Agar and MIC methods against 3 bacteria Staphylococcus aureus, Bacillus cereus, Escherichia coli and 2 fungis Aspergillus niger and Candida albicans.Results and Disscussion: The results showed that, the methanolic extract of S. rhytidea from Sistan and Baluchestan province had high amount of secondary compounds (phenolic and flavonoids: 35.12 ± 2.11 mg GAE/g extract, 29.13 ± 1.12 mg QUE/g extract) and activities (antioxidant activities: IC50= 27.28 ± 2.12 µg/ml, 49.17 ± 2.21 mM Fe2+/mg Sample, and antimicrobial activities against Staphylococcus aureus with the diameter of inhibition zone 25 ± 1.41). Aqueous extract of S. rhytidea from Kerman province had minimum amount of secondary compounds (phenolic and flavonoids: 10.72 ±1.21 mgGAE/g extract, 6.14 ± 0.24 mgQUE/g extract) and activities (antioxidant activities: IC50= 173.12 ± 4.16 µg/ml, 7.66 ± 0.23 mM Fe2+/mg Sample, and antimicrobial activities against Escherichia coli with the diameter of inhibition zone 9 ± 0.19 mm).  The extraction method of the extract and the appropriate solvent play an important role in the extraction of secondary compounds. Methanol solvent has played an important role in the extraction of phenolic and flavonoid secondary compounds, and these compounds have led to antioxidant and antimicrobial properties, so that methanolic extracts have the highest amount of total phenols and flavonoids and the most antioxidant effect. Among the studied extracts, methanolic extract showed the greatest effect in all evaluations. Also, the antioxidant power of methanolic extract of this plant was so high that it was almost close to the antioxidant power of synthetic antioxidants ascorbic acid (10.75 ± 0.98 µg/ml, 65.75 ± 3.35 mM Fe 2+/mg Sample) and BHT (15.26 ± 1.2 µg/ml, 57.96 ± 1.53 mM Fe 2+/mg Sample) in both methods. Ethanolic extract was in the second place for both plant samples and between methanolic and aqueous extracts.Extension:  Overall, based on the results, the Salvia rhytidea can be a suitable candidate for the treatment of diseases caused by oxidative stress, and diseases caused by pathogenic microbes. Also, due to its high potential in eliminating pathogens, this plant can be a suitable alternative to antibiotics. Manuscript profile
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  5 - Extraction of bioactive compounds and determination of antioxidant activity Echium amoenum
  Simin Arabi Assal Farrokh Eslamlou Zahra Ezzatpour Ghadim sarvenaz Maghsoodi
  Introduction: Plants are potential sources of natural antioxidants and produce various antioxidative compounds to counteract reactive oxygen species. Consumption of plant derived antioxidant contributes to reducing risks of certain chronic and degenerative diseases. Ech More

  Introduction: Plants are potential sources of natural antioxidants and produce various antioxidative compounds to counteract reactive oxygen species. Consumption of plant derived antioxidant contributes to reducing risks of certain chronic and degenerative diseases. Echium amoenum also named as Gol-e-gavzaban in persian, is one of the most important species of Boraginaceae family and commonly found in the North of Iran. Echium amoenum is usually used as herbal tea in Iran for conditions such as common cold, bronchitis, sore throat, cough, stress and fatigue. The dried violet–blue petals of Iranian Borage also possess diaphoretic, diuretic, sedative, mood enhancer, antifebrile, laxative, anti-depressant, cardiotonic and blood rectifying properties. Recently, this plant is known as an effective factor against cancer. The present study was conducted at Islamic Azad University of Tehran Medical Sciences. The aim of the present study was to determine total phenolic and flavonoid compounds and antioxidant activity of various extracts of Echium amoenum from Kelardasht region.Experimental: E. amoenum plants were collected from Kelardasht region in Mazandaran province, Iran (2020, June) at the flowering stage, identified by the herbarium of the Research Institute of Forest and Rangelands. The aerial of E. amoenum dried in shade at room for 6 days and ground to a fine powder. The plant sample (50 g) was extracted using Ethanol and Acetone solvents in different concentrations by maceration method. Afterward, the ethanolic and acetonic extracts of E. amoenum were filtered through Whatman No.1 filter paper. The ethanolic extract was evaporated to dryness under reduce pressure (rotary evaporator Buchi R-300, Switzerland) and acetonic extract was concentrated by vaccum oven (Memmert VO49, Germany) at 35°C. Then the extracts were dried by freeze dryer (UO11, Iran) at -40°C and were pulverized. In this study, extraction of total phenolic compounds from E. amoenum by Acetone and Ethanol solvents in three different concentrations (pure, 50% and 75%) were investigated. Total phenolic contents were determined by Folin- Ciocaltue assay and were expressed as mg of gallic acid per g of extract. Then the antioxidant capacity of extracts were assessed by DPPH radical-scavenging activity and reducing power assay and compared with BHT and ascorbic acid standardsResults and Disscussion: In all extracts, the highest total phenolic contents were observed in 50 percentage concentration so that in these conditions, total phenolic contents of acetonic and ethanolic extracts were obtained as 82.9 and 77.3 mg gallic acid equivalents (GAE)/g extract, respectively, ( p ≤ 0.05). Extracts showed antioxidant activity in a dose-dependent manner. Acetonic extract had more antioxidant activity and DPPH radical-scavenging than ethanolic exrtact. The increase antioxidant activity of the plant can be attributed to the high amounts of phenolic and flavonoid compounds.Extension: Echium amoenum can be used as a potential source of phenolic compounds and natural antioxidant. According to the obtained results based on the high antioxidant properties of this plant, it is suggested that with more researches on extract of E. amoenum can be used more and more in the food industry to prevent the oxidative deteriorative activity of food materials. Manuscript profile
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  6 - Eachium amoenum as a functional food ingredient
  Mona Torabi-Toran-Pashtoshti vajihe Fadaei Mohammad reza Eshaghi
  Introduction:  Medicinal plants, either alone or in combination with other drugs, have a growing trend in the treatment of humans. Echium amoenum is one of the annual plants from the Boraginaceae family that in Iran, it is famous as the Gol-e-Gavzaban and is the on More

  Introduction:  Medicinal plants, either alone or in combination with other drugs, have a growing trend in the treatment of humans. Echium amoenum is one of the annual plants from the Boraginaceae family that in Iran, it is famous as the Gol-e-Gavzaban and is the one of the most important medicinal plants in Iranian traditional medicine.  The leaves and flowers organize the useable parts of Gol-e-Gavzaban. In Iranian traditional medicine; the petals of this plant have been used because of strengthening and relaxation effects. The leaves of Gol-e-Gavzaban, with scientific name Borago officianals, have a tongue leaf and full of delicate thorns that gives the rough case to it; and because of this, it is known as Gavzaban. The purpose of this review is the summary description of pharmaceutical effects and functional food and bio-active compounds for introducing of it as a functional food in food industry usage.Results and Disscussion: Echium amoenum like other medicinal plants number the important source of chemical compounds with the potential curative effects. The main bio-active compounds that extracted from Eachium amoenum are poly phenols, Anthocyanidin, Flavonoids, Strols, Saponins, Unsaturated Triphenoids, Unsaturated fatty acids and minor amounts of Pyrrolizidine alkaloid. Rosmarinic acid with Anti_inflammatory effects and Antiviral effects is the main compound of Polyphenols in Gol-e-Gavzaban .This plant contains bioactive compounds that have antioxidant, antibacterial, antiviral, anti-diabetic, anti-inflammatory, analgesic and immune system regulating effects. It was noted that it should be moderated in consumption of this medicinal plant.Extension: Echium amoenum with a wide range of medicinal activities can be considered as a health component. Since the consumption of plant extracts is not pleasant for most people due to their special flavor and odor, so they can be used in combination with food and benefit from their beneficial effects. Also, due to the positive effect of Echium amoenum on the survival of probiotic bacteria, it can be used in the production of synbiotic food. Manuscript profile
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  7 - A review on Iranian Echium amoenum Fisch & C.A. Mey.
  Noraddin Hosseinpour azad Hamed Arastegi Marani Shima Bourang
  Introduction: The Boraginaceae family has about 2,000 species of plants in 100 genera. The plants of this family grow in all temperate and warm regions, especially the Mediterranean region and North and South Africa, Europe, the Canary Islands, and East Asia. Iran is on More

  Introduction: The Boraginaceae family has about 2,000 species of plants in 100 genera. The plants of this family grow in all temperate and warm regions, especially the Mediterranean region and North and South Africa, Europe, the Canary Islands, and East Asia. Iran is one of the important sources of germplasm reserves of a type of plant in this family commonly called Gol Gav Zaban. This plant with the scientific name of Echium amoenum grows in mountainous areas up to 2500 meters above sea level. In order to have full and integrated access to the information on these plants, it is necessary to provide the necessary information in the form of review articles to farmers and researchers.Experimental:  In this research, focusing on some keywords related to this plant such as: botany, chemical compounds, medicinal properties, cultivation method and biotechnology, related articles extracted from scientific sites Like Science direct and PubMed, then used as necessary information.Results and Disscussion: According to the information obtained, in traditional medicine, the petals of this plant are used as a diuretic, analgesic, diaphoretic, and blood pressure reducer. it oilseeds are rich in essential fatty acids such as alpha-linoleic and gamma-linoleic, which are the necessary precursor in the structure of prostaglandins involved in the synthesis of the myelin wall, therefore is used in the preparation of medicinal supplements to prevent neurological diseases such as Multiple Sclerosis (MS).Extension:Due to the nativeness of this plant and its adaptation to most climates of the country, it is one of the potentials in the development of medicinal plants. With the development of cultivation, it is possible to supply a wide range of active ingredients of medicines offered in pharmacies, And can facilitate self-sufficiency in the pharmaceutical fields. Manuscript profile