List of Articles lymphocyte

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  1 - A comparative study between Vancomycin and Enrofloxacin in Heterophil: Lymphocyte ratio, toxic heterophils and Colony counting in experimental Methicillin resistant staphylococcus aureus osteomyelitis in rabbits.
  Taghipour, A., MashhadiRafiei, S., Nasrollahzadeh Masouleh, M. .
  Osteomyelitis is one of the most important life threatening conditions in medicine and veterinary subsequently localized through infection agent following sepsis by bacteria or from trauma, soft tissue, or even following the orthopedic surgery. From among various inflec More

  Osteomyelitis is one of the most important life threatening conditions in medicine and veterinary subsequently localized through infection agent following sepsis by bacteria or from trauma, soft tissue, or even following the orthopedic surgery. From among various inflectional agents, MSSA aureus which is sensitive and resistant to MRSA Methicillin play important role in causing osteomyelitis staphylococcus. Since today it is reported from around the world species resistant to vancomycin which is applied as primary treatment in the cases of acute osteomyelitis resulted from MRSA, efforts to find out alternative treatment is a matter of concern for researchers. In this study, 18 New Zealand white rabbits were divided in to 3 groups of control, vancomycin and enrofloxacin. Rabbits were infected by CFU106 from bacteria in diaphysis of tibia bone and after two weeks ensuring that the acute osteomyelitis induced in tibia bone tissues, rabbits were distributed in 3 groups randomly. Before and after inducing osteomyelitis, inflammatory parameters of heterophil to lymphocyte ratio and toxic changes were measured. After two weeks’ treatment in groups of treatment, two weeks were considered as rest too. after that bones sent for colony counting and microbiology examination. Findings of statistical analysis showed that the difference between control group and vancomycin and control group and enrofloxacin in introduced parameters was significant (P<0.05), however there was not significant difference between the groups of vancomycin and enrofloxacin (P<0.05). It is supposed that vancomycin could be substituted by enrofloxacin in acute osteomyelitis resulted from MRSA. Manuscript profile
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  2 - The effect of weakening the immune system with the drug dexamethasone and high intensity interval training on the maturation of T lymphocytes in the thymus.
  yaser kazemzadeh pegah hooshangi
  10.30495/pah.2023.1988370.1044
  Background and purpose: The thymus is a specialized lymphatic organ in the immune system and plays a vital role in the normal functioning of the immune system. It was observed that 24 and 48 hours after dexamethasone consumption, thymocytes decrease by 55 and 84%, respe More

  Background and purpose: The thymus is a specialized lymphatic organ in the immune system and plays a vital role in the normal functioning of the immune system. It was observed that 24 and 48 hours after dexamethasone consumption, thymocytes decrease by 55 and 84%, respectively, which can be associated with a decrease in the ability of the thymus to mature and differentiate T lymphocytes. The aim of the present study was to investigate the effect of 4 weeks of high intensity interval training on IL-4 and IFN-γ gene expression in the thymus tissue of rats with dexamethasone-induced immune system weakness.Materials and methods: The research samples in the present study consisted of 24 male Wistar rats, which were randomly divided into 3 groups: healthy control group, immunocompromised control group, immunocompromised group + intense periodic activity. Weakening of the immune system of the samples was done by injecting dexamethasone for three days, and high intensity interval training was done for 5 sessions per week, at 85% of the VO2max speed of the samples, for 4 weeks. The data were analyzed using one-way analysis of variance and Tukey's post hoc test at the level of α ≥0.05.Findings: The data showed that the expression of IFN-γ and IL4 gene decreased with dexamethasone injection compared to the control group (p=0.0001), also performing intense intermittent exercise led to a further decrease in IFN-γ and IL4 gene expression in the thymus tissue, but This reduction was not significant (p=0.151).Conclusion: In the present study, it was found that dexamethasone reduces the function of the thymus in the production of inflammatory and anti-inflammatory cytokines, thereby reducing their function in the maturation of lymphocytes. Key words: high intensity interval training, IL-4, IFN-γ, dexamethasone Manuscript profile
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  3 - Compare the effects of two intense interval training (HIIT) protocol on some Immunological indices in young overweight girls
  azizeh ahmadi rasoul dokhtabdiyan
  10.30495/pah.2024.2002899.1068
  this study purpose is to determining the effect of two types high intensity exercise (HIIT) on some Immunological indices in young overweight girls. 24 girls with age 25/75±1/18 y, height: 161/29± 4/23cm, weight 74/51±6/27 kg، fat 30/70± 2/23 More

  this study purpose is to determining the effect of two types high intensity exercise (HIIT) on some Immunological indices in young overweight girls. 24 girls with age 25/75±1/18 y, height: 161/29± 4/23cm, weight 74/51±6/27 kg، fat 30/70± 2/23%, BMI 28/66±1/89 kg/m2 voluntarily participated and randomly divided into three experimental HIIT1 group (n=8), HIIT2 group (n=8) and control group (n=8). Group HIIT1 in each session running four sets 30s with 19 to 20 rate of perceived exertion (RPE) Borg scale and two minutes of rest between sets. HIIT2 group running four sets of 60 s with the same intensity and four minutes rest between sets, training protocol performed three times a week and performed four weeks. 48 hours before and 48 hours after exercise, blood samples were taken. For analyzing data, use Mixed between-within Subjects analysis of variance in level of (P<0.05). mean percent of LYM, NEUT and NEUT levels did not change significantly (P>0.05). The mean of lymphocytes showed significant increase only in Group HIIT2 (P=0.005), difference between groups was not significant (P>0.05). leukocytes in the Both experimental groups was significant increase (P<0.05). The mean of immunoglobulin A in both experimental groups showed a significant increase (p<0.05). In the mean of immunoglobulin G, significant changes were observed only in HIIT1 group (p<0.05). immunoglobulin M did not change significantly in any of the groups (p>0.05). it seems that Short-term HIIT increase leukocyte counts and immunoglobulin A and G to a greater extent than medium-term HIIT. Manuscript profile
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  4 - This study investigated the The effect of eight weeks of resistance training and glutamine supplementation on some hematological factors and maximum strength of male athletes
  mohsen tavakoli
  10.30495/varzesh.2022.1942734.1025
  AbstractThis study investigated the The effect of eight weeks of resistance training and glutamine supplementation on some hematological factors and maximum strength of male athletes. For this purpose For this purpose 24 men at Mashhad were selected on a voluntary basis More

  AbstractThis study investigated the The effect of eight weeks of resistance training and glutamine supplementation on some hematological factors and maximum strength of male athletes. For this purpose For this purpose 24 men at Mashhad were selected on a voluntary basis and according to research requirements through recall informed of the study, that were placed in three groups of eight persons including Control group and placebo group and glutamine group. Resistance training included: 8 moves, 3 sets, 8 to 10 repetitions, with 60% intensity, one maximum repetition and more than 75% incremental. Subjects consumed their supplement and medication 3 days a week. Statistical analysis of the data using the software SPSS version 21 was carried out by Repeated measures and Tukey test at the significant level P>0/05. The findings indicated a significant increase in neutrophil levels, blood lymphocyte and maximal power through resistance training and glutamine consumption, but Resistance training alone could not make significant changes in the factors. Therefore, it is recommended that the coaches, along with the setting of a resistance training program for athletes, also use glutamine supplementation to enhance the ability to exercise, by increasing some of the blood factors leading to the improvement and strengthening of the immune system.Key words: Resistance exercises, neutrophils, lymphocytes, maximal power Manuscript profile
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  5 - The Investigation of the Toxicity of Palladium Nanoparticles on Human Lymphocyte
  maryam zivari fard majid sharifi arian shojaei Seyed Mahdi Rezayat seyyedeh elaheh mousavi Mojtaba Falahati
  10.22034/jna.2020.1893038.1188
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  6 - The Investigation of the Toxicity of Palladium Nanoparticles on Human Lymphocyte
  Maryam Zivari fard Majid Sharifi Arian Shojaei Seyed Mahdi Rezayat Seyyedeh Elaheh Mousavi Mojtaba Falahati
  10.22034/jna.2021.685599
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  7 - بررسی اثر آبلیمو در آب آشامیدنی و پودر آویشن در جیره غذایی بر عملکرد و برخی پارامترهای خونی جوجه‪های گوشتی تحت تنش گرمایی
  ح. بهبودی ا. اسماعیلی‪پور ر. میرمحمودی م. مظهری
  این مطالعه به منظور بررسی اثرات آبلیمو در آب آشامیدنی و آویشن در رژیم غذایی بر عملکرد رشد، غلظت تری‪گلیسرید و کلسترول سرم، هتروفیل، لنفوسیت و نسبت هتروفیل به لنفوسیت و فعالیت آنزیم گلوتاتیون پراکسیداز در جوجه‏های گوشتی تحت شرایط تنش گرمایی انجام شد. آزمایش به صورت ف More

  این مطالعه به منظور بررسی اثرات آبلیمو در آب آشامیدنی و آویشن در رژیم غذایی بر عملکرد رشد، غلظت تری‪گلیسرید و کلسترول سرم، هتروفیل، لنفوسیت و نسبت هتروفیل به لنفوسیت و فعالیت آنزیم گلوتاتیون پراکسیداز در جوجه‏های گوشتی تحت شرایط تنش گرمایی انجام شد. آزمایش به صورت فاکتوریل 3 × 2 با دو سطح آبلیمو (0 و 2 ملی‏لیتر در لیتر آب آشامیدنی) و سه سطح پودر آویشن (0، 5/0 و 1 درصد جیره غذایی) انجام شد. هر تیمار شامل 4 تکرار (9 پرنده در هر تکرار) بود. پرندگان از 25 تا 42 روزگی در دمای 2 ± 34 درجه سانتی‪گراد (از ساعت 9 تا 17) قرار گرفتند. خوراک مصرفی، اضافه وزن بدن، ضریب تبدیل غذایی، نسبت هتروفیل به لنفوسیت، فعالیت آنزیم گلوتاتیون پراکسیداز و غلظت کلسترول سرم تحت تأثیر اثرات آبلیمو و آویشن قرار نگرفتند (05/0P>) در حالیکه اثر ترکیبی این دو ماده افزودنی باعث بهبود عملکرد و کاهش نسبت هتروفیل به لنفوسیت و غلظت تری‏گلیسرید سرم شد (05/0P≤). استفاده همزمان 5/0 درصد آویشن و 2 میلی‏لیتر در لیتر آبلیمو خوراک مصرفی و اضافه وزن بدن را به ترتیب به میزان 229 و 165 گرم افزایش داد. افزودن 5/0 و 1 درصد آویشن به جیره غذایی و 2 میلی‏لیتر در لیتر آبلیمو به آب آشامیدنی باعث کاهش غلظت تری‏گلیسرید سرم به ترتیب به میزان 8/9، 1/11 و 5/8 میلی‏گرم در دسی‏لیتر شد. نتایج این آزمایش نشان داد که استفاده همزمان 5/0 درصد آویشن به جیره غذایی و 2 میلی‏لیتر در لیتر آبلیمو به آب آشامیدنی یک برنامه مدیریتی بالقوه‏ای را جهت جلوگیری از کاهش عملکرد ناشی از تنش گرمایی بر جوجه‏های گوشتی فراهم می‏کند. Manuscript profile
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  8 - اثر تیمول و کارواکرول بر عملکرد تولید، فعالیت آنزیم‪های آنتی‪اکسیدانی و متابولیت‪های خونی جوجه‌های گوشتی تحت تنش گرمایی
  ح. سعادت شاد م. مظهری ا.ع. اسماعیلی‪پور ح. خسروی‪نیا
  مطالعه حاضر به منظور بررسی اثر تیمول و کارواکرول بر عملکرد تولید، فعالیت آنزیم‪های آنتی‪اکسیدانی و متابولیت‪های خونی جوجه‪های گوشتی تحت تنش گرمایی طراحی شد. جوجه‪ها تا 25 روزگی با جیره استاندارد تجاری تغذیه شده و سپس به یک آزمایش فاکتوریل (2×3) در قالب طرح کاملاً More

  مطالعه حاضر به منظور بررسی اثر تیمول و کارواکرول بر عملکرد تولید، فعالیت آنزیم‪های آنتی‪اکسیدانی و متابولیت‪های خونی جوجه‪های گوشتی تحت تنش گرمایی طراحی شد. جوجه‪ها تا 25 روزگی با جیره استاندارد تجاری تغذیه شده و سپس به یک آزمایش فاکتوریل (2×3) در قالب طرح کاملاً تصادفی با سه سطح کارواکرول (0، 300 و500 میلی‌گرم در هرکیلوگرم خوراک) و دو سطح تیمول (0 و250 میلی‌گرم درهرکیلوگرم خوراک) در چهار تکرار نه پرنده‪ای اختصاص یافتند. جهت ایجاد تنش گرمایی، جوجه‌ها از 26 روزگی تحت دمای 35 درجه سانتی­گراد به مدت 8 ساعت در روز قرار گرفتند. نتایج آزمایش نشان داد که مصرف کارواکرول اثر معنی‪داری بر پارامترهای عملکردی نداشت، اما مصرف 250 میلی­گرم تیمول منجر به افزایش معنی‌دار وزن روزانه و کاهش معنی‌دار ضریب تبدیل غذایی به میزان 4 و 6 درصد شد (05/0>P). ­گلبول­های سفید، قرمز، هموگلوبین، هماتوکریت و لنفوسیت تحت تأثیر تیمارها قرار نگرفتند، اما هتروفیل و نسبت هتروفیل به لنفوسیت با مصرف تیمول و کارواکرول به طور معنی‌داری کاهش یافت (05/0>P). مصرف تیمول و کارواکرول، کلسترول سرم خون را کاهش داد (05/0>P)، اما اثری بر تری‌گلیسرید و لیپوپروتئین‌های با چگالی کم و زیاد و گلوکز خون نداشت. هر دو مکمل تیمول و کارواکرول به طور معنی‌داری فعالیت آنزیم گلوتاتیون پراکسیداز را در مقایسه با گروه شاهد افزایش دادند (05/0>P). درصد لاشه و سینه با مکمل تیمول افزایش یافت (05/0>P)، اما اثری بر وزن نسبی اندام‪های داخلی مشاهده نشد. بنابراین مصرف 250 میلی­گرم تیمول می‌تواند از طریق بهبود عملکرد و پتانسیل آنتی‪اکسیدانی خون در جهت رفع اثرات منفی تحت تنش گرمایی مؤثر باشد. Manuscript profile
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  9 - The Effects of Fe2ZnO4 Nanoparticles on Blood Cells of Male Wistar Rat
  A. Gerami M. Setorki Z. Hooshmandi
  Due to increased production and use of nanoparticles, extensive studies are needed to determine their toxicity and negative effects. The aim of this study was to evaluate the effect of Fe2ZnO4 nanoparticle on blood cell counts and hematocritpercentage. In this experimen More

  Due to increased production and use of nanoparticles, extensive studies are needed to determine their toxicity and negative effects. The aim of this study was to evaluate the effect of Fe2ZnO4 nanoparticle on blood cell counts and hematocritpercentage. In this experimental study, 24 male Wistar rats were randomly divided into groups of 8 rats. Group 1 received 0.5 ml of saline. Group 1 and 2 received 0.5ml of distillated water containing 100 and 200 ppm Fe2ZnO4for 7 successive days. Red blood cell count, white blood cell count and differential count, platelet count and hematocrit were determined 2, 7 and 14 days after treatment. Fe2ZnO4 lead to a significant reduction in RBC and a significant increase in WBC. Nanoparticles exposure increased neutrophil and lymphocyte percentage which reflects the heightened response of innate immune system against nanoparticles. Fe2ZnO4 also caused a significant reduction in blood platelet count and 200 ppm dose caused higher reduction (p Manuscript profile