List of Articles lipid trends

• Open Access Article
  • Abstract Page
  • Full-Text
  
  1 - Study on the effects of consumption of milk containing Lactobacillus acidophilus on serum lipid trends and weight gain of rats fed high lipid diet
  حمید Mirzaei مهران Mesgari abbasi عیسى Tajmohammadi
        Despite the significant progresses made in the reduction of mortality due to cardiovascular diseases, they are still the primary cause of death in many countries and hyperlipidemia is an important causal agent of cardiovascular diseases. Probio More

        Despite the significant progresses made in the reduction of mortality due to cardiovascular diseases, they are still the primary cause of death in many countries and hyperlipidemia is an important causal agent of cardiovascular diseases. Probiotics are food supplements containing live microbes which balance the flora of the digestive system and produce positive effects in the host body. L.acidophilus is a beneficial bacterium used in the production of probiotic products .The aim of this study is to evaluate the effects of consumption of milk containing L.acidophilus on serum lipid trends of rats fed high lipid diet. This is an experimental study in which 30 male albino Wistar rats with a body weight of 200±15 gr. were randomly allocated to two groups of treatment and control each containing 15 rats which were adapted to a high lipid diet (11.74%) and water containing 25% milk within a week. Rats in both groups received high lipid diet and water containing 25% milk for 60 days with the exception that rats in the treatment group received water containing L. acidophilus at a level of 109 CFU/rat/day throughout the experiment. Independent t-test revealed that at a level of α= 0.05, mean levels of total cholesterol and LDL-C of rats in the treatment group was significantly lower than the control group (p<0.05), and HDL-C of rats in the treatment group was significantly higher than the control group (p<0.05), but the mean levels of triglyceride and VLDL-C was not significantly different. Also increase in body weight was significantly higher in the treatment group compared with the control group (p<0.01). On the whole, long term daily consumption of milk containing L. acidophilus improves serum lipid trends by lowering total cholesterol level and LDL-C and increasing HDL-C and also increases the rate of body growth.   Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  2 - Study on the effect of Lactobacillus casei o1 fermented milk consumption on lipid pattern of rats nourished with cholesterol enriched diet
  حمید Mirzaei بهرام Amouoghli Tabrizi مهدی Rafiei
  The aim of this study was to evaluate the effects ofconsumption of different amounts of fermented milk by L.casei on serum lipid trends including total cholesterol, LDL-C, HLD-C, VLDL-C and triglyceride in the serum of rats fed 1 and 2% cholesterol enriched diet. For th More

  The aim of this study was to evaluate the effects ofconsumption of different amounts of fermented milk by L.casei on serum lipid trends including total cholesterol, LDL-C, HLD-C, VLDL-C and triglyceride in the serum of rats fed 1 and 2% cholesterol enriched diet. For this purpose 49 male albino wistar rats with a body weight of 200±15 gr were randomly allocated to seven groups each containing 7 rats and adapted to new conditions during a week. Rats in the first group (control group) received commercial diet and water for 30 days, the second to fourth groups received diet enriched with 1% cholesterol and rats in the fifth to seventh groups received diet enriched with 2% cholesterol. Each rat in the fourth and seventh groups (double dose receiving treatment groups) consumed fermented milk containing 4×108 CFU bacteria per day, rats in the third and sixth groups (single dose receiving treatment groups) consumed fermented milk containing 2×108 CFU bacteria per day and in the second and fifth groups (sham group) consumed sterilized milk instead of fermented milk. According to the statistical tests, one way analysis of variance and Tukey at a level of α= 0.05, mean levels of total cholesterol and LDL-C of rats in the  double dose receiving treatment groups and single dose receiving treatment groups were significantly lower and mean level of HDL-C was significantly higher than sham group (p<0.05). In the rats fed  1% enriched cholesterol, mean levels of VLDL-C and triglyceride of rats in the  double dose receiving treatment groups were significantly lower than sham group (p<0.05). Long term daily consumption of milk fermented by L.casei improves serum lipid trends by lowering total cholesterol and LDL-C level and by increasing HDL-C level. The effectiveness of this probiotic on lipid trends is dose dependent. Manuscript profile