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      • Open Access Article

        1 - Protective Effects of Voluntary Exercise and extract of Salvia officinalis on diazinon induced Hepatotoxicity in Rats
        Esmaeil Fatahi Akbar Hajizadeh Mogadam Tahereh Bagery
        Inroduction & Objective:Diazinon (DZN) is organophosphate pesticides which as environmental pollutants cause oxidative stress. This study was done to determinate protective effects of exercise programand Salvia officinalis extract on liver tissue damages from diazinon.M More
        Inroduction & Objective:Diazinon (DZN) is organophosphate pesticides which as environmental pollutants cause oxidative stress. This study was done to determinate protective effects of exercise programand Salvia officinalis extract on liver tissue damages from diazinon.Material and Methods:: in this study, 35 wistar rats randomly divided into equal groups including: control, DZN, DZN - extract, exercise- DZN, exercise- extract – DZN.  Salvia officinalis extract with 100 mg/kg dosage for 4 weeks and DZN with 200 mg/kg dosage for once via intraperitoneally injection. Animals were sacrificed 24 hours after the last injection and blood samples were collected from the heart, sera were used to measure the concentrations of ALT and AST via RIA method.   Then liver removed of body and sections were prepared for histopathological studies. Data analyzed by one-way ANOVA and Duncan.Results: Number of hepatocytes and sinusoids capillary significantly reduced in DZN group compared to control (pConclusion: Salvia officinalisextract and exercise improves the body's antioxidant status and reduces of oxidative stress against diazinon. Manuscript profile
      • Open Access Article

        2 - Comparing the effectiveness of Salvia officinalis herbal mouthwash and chlorhexidine in reducing plaque and inflammation: A clinical trial
        Sepehr Sadeghi vahid Esfahanian Motahareh Damavandi
        Background: This study aimed to compare the antiplaque and anti-inflammatory effects of Salvia officinalis (S. officinalis) herbal mouthwash and chlorhexidine (CHX).Materials and Methods: This double-blind clinical trial was conducted on 63 patients without advanced per More
        Background: This study aimed to compare the antiplaque and anti-inflammatory effects of Salvia officinalis (S. officinalis) herbal mouthwash and chlorhexidine (CHX).Materials and Methods: This double-blind clinical trial was conducted on 63 patients without advanced periodontitis and with at least 20 caries-free teeth without extensive restorations. Patients were assigned randomly to 3 groups (n=21) of 0.2% CHX, S. officinalis mouthwash, and saline. The baseline plaque index (PI) was set to zero by scaling and prophylaxis. After recording the Gingival index (GI), patients learned to use the mouthwash (10 cc) for 60 seconds twice daily for 15 days without using toothbrushing or other plaque control methods. PI and GI were then measured again. Data was analyzed using ANOVA, independent t-test, and paired t-test statistical methods at a significance level of P<0.05.Results: Groups showed no significant difference in GI (P>0.05) at baseline. At day 15, the PI of the CHX group was significantly lower than the S. officinalis group (P<0.001). The PI of the CHX and S. officinalis groups was also lower than that of the saline group (P<0.05). GI was not significantly different between CHX and S. officinalis groups (P>0.05). The GI of the CHX group was lower than that of the control group (P<0.05) Further significant differences were not noted (P>0.05).Conclusion: Although inferior to CHX, S. officinalis mouthwash effectively decreased the PI and GI of patients. Manuscript profile
      • Open Access Article

        3 - Investigating the chemical and microbial parameters of spoilage and determining the shelf life of Cyprinus carpio fillet Under the influence of carboxymethyl cellulose coating containing Salvia officinalis extract
        Moammad Esmaeili Yasaman Fahim Dezhban
        In the present study, the effect of carboxymethyl cellulose oral active coating containing salvia officinalis extract on the quality and shelf life of common carp fillet during the storage period in the refrigerator (4±1℃) was investigated. Common carp fillets in More
        In the present study, the effect of carboxymethyl cellulose oral active coating containing salvia officinalis extract on the quality and shelf life of common carp fillet during the storage period in the refrigerator (4±1℃) was investigated. Common carp fillets in five control groups were treated with carboxymethyl cellulose coating without extract and containing 0.5% and 1% sage extract and kept in refrigerator for 12 days, chemical (pH, TVN, PV, TBA) and microbial (Total and Psychrophilic bacterial load) indicators were investigated. The results of this research confirm the better performance of carboxymethyl cellulose coating containing 1% sage extract compared to other treatments; So that the chemical indices and amounts of total and Psychrophilic bacteria as microbial indices of quality control of had better results than other treatments until the end of the storage period and showed was able to provide acceptable quality by reducing the Total bacterial amount and the amount of Psychrophilic bacteria in the samples. According to the results of the evaluation chemical indicators affecting spoilage, the application of carboxymethyl cellulose coating containing 1% of sage extract can more effectively cause damage by controlling and reducing the oxidation of lipids than other treatments. Maintain the quality of common carp fillets during the storage period. Therefore, Salvia officinalis extract, having antioxidant and antimicrobial properties, as a natural biological preservative in combination with coating of carboxymethyl cellulose, can be used as a method to maintain the quality and increase the shelf life of common carp fillets during storage in the refrigerator. Manuscript profile
      • Open Access Article

        4 - Essential oil composition and antioxidant activity of Salvia officinalis L. and Achillea millefoliom L. from Kerman province
        syed Mohammad Ali Vakili Shahrbabaki
        Salvia officinalis L. and Achillea millefoliom L. have been reported as  an antioxidant, anti infection and anti inflammatory. In this study aerial parts of both of plants in blooming were collected in June 2014 (1700m) from their natural habitats in Kerman provinc More
        Salvia officinalis L. and Achillea millefoliom L. have been reported as  an antioxidant, anti infection and anti inflammatory. In this study aerial parts of both of plants in blooming were collected in June 2014 (1700m) from their natural habitats in Kerman province. Essential oils were obtained by hydro-distillation (Clevenger apparatus) and were analyzed by GC/MS. Total phenol content was measured by Folin–Ciocalteau method and their antioxidant activity was measured by DPPH. Results were showed that the oil of Salvia officinalis L. had higher amount of phenolic compounds (1.8 mg E GA/ml) and antioxidant activity(99.48% radical scavenging). The camphor (33.6%), α-tujene (25.4%) and 1,8-cineole(13.8%) were the most components of S.officinalis L. essential oil, respectively and the 1,8-cineole (22.3%), carvacrol (15%) and γ-terpinene were the most components of A.millefolium L. These results were confirmed that the secondary metabolites of these plants possess antioxidant activity and could be used as a natural antioxidant ingredient in food and drug industries. Manuscript profile
      • Open Access Article

        5 - Effect of irrigation frequency on yield and chemical compositions of the essential oil from Salvia officinalis L.
        najmeh vosoughi Masoud gomaria Prof. Abdollah Ghasemi Pirbalouti shahab khaghani fatemeh Malekpoor
        Drought stress is as one of the most important limited factors that in agriculture systems can cause damage to growth, yield and secondary metabolites in medicinal and aromatic plants. A filed experiment to study on effect of irrigation frequencies, including 4, 6, and More
        Drought stress is as one of the most important limited factors that in agriculture systems can cause damage to growth, yield and secondary metabolites in medicinal and aromatic plants. A filed experiment to study on effect of irrigation frequencies, including 4, 6, and 8 every days on quantity and quality of the essential oil from the aerial parts of sage (Salvia officinalis L.) was done based on a randomized complete block design (RCBD) in three replications at the research field at Islamic Azad University of Shahrekord, southwestern Iran in 2016. The leaves of sage were harvested at early flowering and the essential oil from the dried leaves was subjected to hydrodistillation using a Clevenger-type apparatus. The essential oils under different treatments were analyzed by GC and GC/MS. Results indicated that irrigation frequencies levels had significant effects on essential oil yield and percentages of 1,8-cineole (as the main constituent in the oil), limonene and α–humulene. The highest yield of the essential oil and the maximum contents of 1,8-cineole (11.05%), limonene (2.67%) and α–humulene (1.32%) were obtained from treatment of eight every days of irrigation. Probably, it seems that increased irrigation intervals (mild drought stress) can be effective in quantitative and qualitative properties of essential oil from sage (Salvia officinalis L.). Manuscript profile
      • Open Access Article

        6 - ترکیبات شیمیایی و فعالیت ضد میکروبی اسانس (Salvia officinalis L) و (Salvia virgata Jacq)
        احمدرضا گلپرور امین هادی پناه محمدمهدی قیصری داوود نادری شیما رحمانیان مجتبی خرمی
        مقدمه و هدف : (Salvia officinalis L.) و (Salvia virgata Jacq) گیاهان چند ساله و معطر از خانواده نعناع (Lamiaceae) می­باشد. هدف از این تحقیق شناسایی ترکیبات شیمیاییو فعالیت ضد میکروبی دو گونه Salvia بود. روش تحقیق: قسمتهای هوایی S. officinalis و S. virgata  به و More
        مقدمه و هدف : (Salvia officinalis L.) و (Salvia virgata Jacq) گیاهان چند ساله و معطر از خانواده نعناع (Lamiaceae) می­باشد. هدف از این تحقیق شناسایی ترکیبات شیمیاییو فعالیت ضد میکروبی دو گونه Salvia بود. روش تحقیق: قسمتهای هوایی S. officinalis و S. virgata  به وسیله دستگاه کروماتوگرافی گازی متصل به طیف سنج جرمی (GC/MS) مورد تجزیه و شناسایی قرار گرفت. خاصیت ضد باکتریایی با استفاده از سویه باکتری­های استاندارد شامل Staphylococcus epidermidisوEscherichia coliو قارچ های Alternaria alternataوPenicillium funiculosumدردو روش دیسک دیفیوژن و چاهک گذاریمورد بررسی قرار گرفت. نتایج و بحث: نتایج بدست آمده از این تحقیق نشان داد که 42 ترکیب در اسانس S. officinalis و 29 ترکیب در اسانس S. virgata  به  ترتیب شناسایی شد. ترکیبات اصلی اسانس S. officinalis شامل α-thujone  (18/37%)، 1,8-cineole  (71/12%)، β-thujone  (10/9%)، camphene (54/5%) و viridiflorol  (33/5%) شناسایی شد. و ترکیبات اصلی اسانس S. virgata  شامل caryophyllene oxide (23/30%)، β-caryophyllene (63/22%)، sabinene (82/11%)، 1-octan-3-ol (64/6%)، thujene (28/6%) و terpinene-4-ol (25/5%) شناسایی شد. اسانس  S. officinalisو S. virgata   در روش چاهک گذاری بیشترین ویژگی ضد میکروبی را برای S. epidermidisنشان داده و کمترین اثر را بر E. coli داشت. در روش دیسک دیفیوژن  بیشترین ویژگی ضد میکروبی اسانس  S. officinalisو S. virgata   بر ضد  E. coliوP. funiculosum (PTCC NO. 5301) بوده و کمترین اثر را بر A. alternate  نشان داد. توصیه کاربردی/صنعتی: در مجموع اسانس S. officinalisخاصیت ضد میکروبی بیشتری نسبت به گیاهS. virgata   نشان داد. Manuscript profile
      • Open Access Article

        7 - اثرات جاسمونیک و سالیسیلیک اسید بر خاصیت فیتوشیمیایی برگ مریم گلی (Salvia officinalis L)
        مهدی رحیم ملک شکوفه آزاد مهراب یادگاری عبدالله قاسمی پیربلوطی
        مقدمه و هدف: مریم گلی (officinalis L. Salvia) گیاهی است چند ساله و علفی، این گیاه از تیره نعنائیان است. هم­چنین این گیاه تا چهار سال بازدهی اقتصادی دارد. امروزه استفاده از تنظیم کننده های رشد گیاهی نقش مهمی در افزایش ترکیبات ثانویه گیاهان به خصوص اسانس ها دارد از مه More
        مقدمه و هدف: مریم گلی (officinalis L. Salvia) گیاهی است چند ساله و علفی، این گیاه از تیره نعنائیان است. هم­چنین این گیاه تا چهار سال بازدهی اقتصادی دارد. امروزه استفاده از تنظیم کننده های رشد گیاهی نقش مهمی در افزایش ترکیبات ثانویه گیاهان به خصوص اسانس ها دارد از مهمترین تنظیم کننده های رشد گیاهی که کاربرد وسیعی در گیاهان دارویی دارند می توان به اسید جاسمونیک و سالیسیلیک اشاره نمود.روش تحقیق: به منظور بررسی اثرات مقادیر مختلف سالیسیلیک اسید و جاسمونیک اسید بر خاصیت فیتوشیمیایی برگ مریم گلی آزمایشی در شرایط گلدانی در مزرعه­ی تحقیقاتی دانشگاه هرمزگان انجام شد.  این آزمایش در قالب طرح کاملاً تصادفی با 10 تیمار و در 3 تکرار اجرا شد. تیمارهای سالیسیلیک اسید در چهار سطح (1، 10، 20 و 40 مول بر لیتر) و جاسمونیک اسید در چهار سطح (50، 100، 200 و 400 میکرولیتر) بر روی گیاه مریم گلی محلول­پاشی شد. نمونه های اندام هوایی با استفاده از دستگاه کلونجر اسانس گیری گردید سپس جهت شناسایی ترکیبات به دستگاه کروماتوگرافی جرمی (GC-MS) تزریق شد.نتایج و بحث: بر اساس نتایج به­دست آمده نشان داد اسید جاسمونیک و اسید سالیسیلیک  در افزایش میزان آلفا-پینن، کامفن، بتا-پینن، 1،8-سینئول، سیس- توژان، ترانس- توژان، بورنئول، بورنئول-استات و کامفور  تأثیر داشته؛ به طوری که با اعمال تیمار اسید جاسمونیک  50 میکرولیتر باعث افزایش بتا-پنین و تیمول شد.توصیه کاربردی/صنعتی: با توجه به نتایج حاصل از تحقیق حاضر توصیه می­شود مطالعات بیشتری در خصوص اثرات تنظیم کننده های رشد جدید مانند اسید جاسمونیک و سالیسیلیک در غلظت های مختلف از این آزمایش بر ماده موثره گیاهان دارویی انجام شود. Manuscript profile
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        8 - فعالیت ضد میکروبی عصاره استونی Salvia officinalis در برابر جدایه های بیماریزا
        قزلباش ق. ر پریشانی م. ر فویوانی م .ح
        مقدمه وهدف: Salvia officinalis  به عنوان یک داروی سنتی در درمان برخی از بیماریها در کشورهایی از جمله لبنان، سوریه، اردن و .... شناخته شده است. به علاوه S. officinalis  در مطالعات مختلف برای بررسی تاثیرات دارویی مورد آزمایش قرار گرفته است. هدف در این مطالعه برر More
        مقدمه وهدف: Salvia officinalis  به عنوان یک داروی سنتی در درمان برخی از بیماریها در کشورهایی از جمله لبنان، سوریه، اردن و .... شناخته شده است. به علاوه S. officinalis  در مطالعات مختلف برای بررسی تاثیرات دارویی مورد آزمایش قرار گرفته است. هدف در این مطالعه بررسی فعالیت ضد باکتریایی این گیاه در برابر تعدادی از باکتریها بوده است. روش تحقیق: سه عصاره مختلف ( عصاره آبی، استون و اتانولی) از نظر ویژگیهای ضد باکتری در برابر باسیلوس آنتراسیس، باسیلوس سرئوس، اشریشیاکلی و استافیلوکوکوس اورئوس با روش انتشار دیسکی مورد ارزیابی قرار گرفتند. نتایج و بحث: عصاره های اتانولی تاثیرات ضد باکتریایی متوسطی را نشان دادند در حالیکه عصاره های استونی به خصوص عصاره برگها تاثیر قدرتمندی در این زمینه داشتند. از سوی دیگر عصاره های آبی هیچ فعالیت ضد باکتریایی در برابر باکتریهای مورد آزمایش نشان ندادند. نتایج نشان دهنده فعالیت بازدارندگی عصاره استونی با MIC معادل 10 میلی گرم در میلی لیتر برای باسیلوس آنتراسیس و MIC معادل 30 میلی گرم در میلی لیتر برای استاف اورئوس بود. میکروارگانیسمهای گرم منفی حساسیت بیشتری نسبت به عصاره ها نشان دادند. در مجموع می توان گفت که عصاره های استخراج شده توسط حلالهای آلی به خصوص استون می تواند به عنوان یک ترکیب ضدباکتری مورد استفاده قرار گیرد و نیز به این نکته می توان اشاره کرد که چنانچه قطبیت حلال کاهش می یابد ترکیبات ضد باکتری و بنابراین فعالیت عصاره افزایش نشان می دهد. توصیه های کاربردی/صنعتی: عصارهSalvia officinalisمی تواند به عنوان پماد برای درمان زخم استفاده شود و به عنوان یک داروی جدید در برابر باسیلوس آنتراسیس معرفی شود. Manuscript profile
      • Open Access Article

        9 - The effect of electromagnetic waves on the rate of germination and the anatomical structure of two types of salvia plants
        zahra goodarzi Sedigheh Arbabian masoomeh mirzai ahmad majd
        In order to investigate the effect of electromagnetic waves on the germination of ornamental and medicinal sage seeds, an experiment was conducted in the form of a completely randomized design in three replications in the greenhouse of the Karaj Botanical Garden. The ex More
        In order to investigate the effect of electromagnetic waves on the germination of ornamental and medicinal sage seeds, an experiment was conducted in the form of a completely randomized design in three replications in the greenhouse of the Karaj Botanical Garden. The experimental treatments included: control, electromagnetic waves of 3 millitesla for a period of 30 and They were 60 minutes. After the test period, germinated seeds were counted and traits such as germination percentage, germination speed, length of roots and stems, fresh weight and dry weight of roots were measured.The results showed that the applied treatments had a significant effect on germination and the traits measured on the seeds compared to the control, and the treatment of 60 minutes of electromagnetic waves had the greatest effect on all the traits measured. concluded that the treatment of sage seeds by electromagnetic waves can improve and stimulate and increase germination parameters and growth dynamics in sage plants. Manuscript profile
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        10 - Assessment of Qualitative and Quantitative Composition of Essential Oil of Three Salvia Species
        FARAHNAZ FARAJZADEH HOSSEIN ALI ASADI-GHARNEH NASER SABAGHNIA
      • Open Access Article

        11 - The study of effects Erath worm, compost and soil tissue on soil trairts, quantity and quality yield salvia officinalis
        Ali Eftekhari
        In order to investigate the effects of compost and erath worm on and quantity and quality yield of salvia officinalis, an expermintal was carred out based on factoriel in completely randomized block disgn with three replication in experimental in the Challus University More
        In order to investigate the effects of compost and erath worm on and quantity and quality yield of salvia officinalis, an expermintal was carred out based on factoriel in completely randomized block disgn with three replication in experimental in the Challus University in 2014. The treatments were included 1-Erath worm with application levels (0.10 and 20 class) 2-compost with consumption levels (0 and 30g per pot) and 3-type soil tissue (sand and clay). The evulluation of charecteristics were included, dry matter of plant, rate of essence, CEC, OM%, N%, pH and EC. The hieghest of dry matter of plant and rate of essence with interaction effects treatment application Erath worm and consuimption of 30g compost was obtained. Maximum N percentage of soil (0.47), OM percentage (1.53), CEC (23.66) in interaction effects 20 class erath worm with 30g compost achived application of earth worm induce EC increased significantly. Increas dry matter of plant and rate essence that was affected Application earth worm and compost consuimption induce to drymatter of plant and rate essence increased because CEC, %OM and %N soil with treatments of application earth worn with compost were increasd. Manuscript profile
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        12 - The study of effects Erath worm, compost and soil tissue on soil traits, quantity and quality yield salvia officinalis
        M. Sharif Moghadasi S. Azizi,
              In order to investigate the effects of compost and earth worm on and quantity and quality yield of salvia officinalis, an experimental was carried out based on factorial in completely randomized block design with three replications in expe More
              In order to investigate the effects of compost and earth worm on and quantity and quality yield of salvia officinalis, an experimental was carried out based on factorial in completely randomized block design with three replications in experimental in the Challus University in 2014. The treatments were included 1-Erath worm with application levels (0.10 and 20 class) 2-compost with consumption levels (0 and 30g per pot) and 3-type soil tissue (sand and clay). The evaluation of characteristics was included, dry matter of plant, rate of essence, CEC, OM%, N%, pH and EC. The highest of dry matter of plant and rate of essence with interaction effects treatment application Erath worm and consumption of 30g compost was obtained. Maximum N percentage of soil (0.47), OM percentage (1.53), CEC (23.66) in interaction effects 20 class earth worm with 30g compost achieved application of earth worm induce EC increased significantly. Increase dry matter of plant and rate essence that was affected Application earth worm and compost consumption induce to dry matter of plant and rate essence increased because CEC, %OM and %N soil with treatments of application earth worn with compost were increased.       Manuscript profile
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        13 - Effect of Ascorbate and Gibberellin on antioxidant activity, proline and soluble carbohydrates in Sage (Salvia officinals L.) under salt stress conditions
        R. Hemati A. Pazoki
        To investigate the effect of ascorbate and gibberellin on some physiological characteristics of the Salvia medicinal plant under salt stress conditions, an experiment was done at municipal greenhouse No­­ 15 in March 2013. The experiment was as factorial based o More
        To investigate the effect of ascorbate and gibberellin on some physiological characteristics of the Salvia medicinal plant under salt stress conditions, an experiment was done at municipal greenhouse No­­ 15 in March 2013. The experiment was as factorial based on completly randomized  designe (CRD) with four replications. Experimental factors including salinity levels in 4 levels (0, 25, 50 and 75 mM Nacl), ascorbate in 2 levels (0 and 4 mM) and gibberellin in two levels (0 and 2 mM). The mean comparison  showed that the main effect of salinity showed that the cause  of the decline of activity of antioxidant enzymes and increase the amount of soluble sugars and proline. . Except of the three double interaction effect of factors on proline and soluble sugars in other cases, there was significant difference on other traits. As well, instead of triple interaction of treatments on, proline, catalase and ascorbate peroxidase in other cases no significant difference was observed. In this case the maximum amount of  proline production (12/67 mg/g fw), catalase activity (19/68 mg/protein. min) and ascorbate peroxidase (61/25 mg/protein. min) conducted in 75 mM Nacl and ascorbate and gibberellin application.As a result of the application of ascorbate as a strong antioxidant and GA as growth regulators, foliar damage due to stress, these two compounds were offset and in the absence of ascorbate and GA was given to the plant, the activity of antioxidant enzymes decreased.   Manuscript profile
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        14 - The Protective Effects ofSalvia officinalisExtractonthe PancreaticTissueofRatsPoisonedbyDiazinon
        اسماعیل فتاحی آنا خشکفا
        Diazinon is organophosphates that causes inhibition of acetylcholinesterase and induceofoxidative stress intheorganismThisstudy was done todeterminethe effects ofSalvia officinalisextractonpancreatictissueinratspoisonedbydiazinon.This experimental study, 35 adult male r More
        Diazinon is organophosphates that causes inhibition of acetylcholinesterase and induceofoxidative stress intheorganismThisstudy was done todeterminethe effects ofSalvia officinalisextractonpancreatictissueinratspoisonedbydiazinon.This experimental study, 35 adult male rats were divided into three equal groups;control, Diazinon(DZN), Diazinon-extractAnimals in experimental groups,were received anintraperitoneal injection of 200 mg/kg DZNfor one time and extractat dose of 100 mg / kg for four weeks(five days per week).Rats were sacrificed24 h after latest injection. Pancreatictissuesections were provided to microscopic studies.  Data were analyzed using of one-way ANOVA.Number and diameter ofIslets of Langerhans and Blood vesselsand number of acini cells in the DZN group sig­nificantly decreasedcompared to the control(pSalvia officinalisextracthaveprotective effect on pancreatic. Manuscript profile
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        15 - The Effects of Hydroalcoholic Extract of Salvia officinalis on Liver Tissue and Cu, Fe, Zn and Mg Elements in Male Rats
        شهرزاد خاکپور مریم خسروی معصومه میرزائی محیا نجاری
        The imbalance between the production of free radicals and antioxidant can be the cause of oxidative stress.Oxidative stress induces different diseases and tissue damages. Isoniazid has been used for the purpose of producing free radicals. In the present study, we invest More
        The imbalance between the production of free radicals and antioxidant can be the cause of oxidative stress.Oxidative stress induces different diseases and tissue damages. Isoniazid has been used for the purpose of producing free radicals. In the present study, we investigated the effects of Salvia officinalis hydroalcoholic extract on blood elements such as Fe, Mg, Zn and Cu. In this study, 63 male rats were used and divided in 9 groups; in each group 7 rats were included. Isoniazid 50mg/kg was orally administered to rats continuously once per day for 28 days using a feeding atraumatic needle. The experimental groups received for 28 days,Salvia officinalis hydroalcoholic extract with the doses 100, 250 and 400 mg/kg intraperitoneally, and also some experimental groups were coadministered with different doses of the extract and isoniazid; the results of serum Fe, Mg, Zn and Cu were compared with the control and sham groups, as well. Also, the animal livers of all groups were separated and dissected for the histopathological studies. Zn and Cu were increased significantly in the treated-groups with Salvia officinalis, but the levels of Fe and Mg showed a significant decrease in the experimental groups treated with all the doses of Salvia officinalis hydroalcoholic extract. It seems that tannin and bitter compounds of Salvia officinalis hydroalcoholic extract are the main agents to alternate the blood element levels. Manuscript profile
      • Open Access Article

        16 - Effect of Salvia officinalis Extract with Vacuum Packaging on Physicochemical Properties of Hypophthalmichthys Molitrix Fish During Refrigeration Storage
        Fateme Kolaie moakhar Mehran Moslemi Rozbeh Abedi
        In this project, the effect of salvia officinalis extract coating in three treatments (at concentration of 1, 2, and 3%, respectively) was investigated on chemical and microbiological characteristics of fillets prepared from hypophthalmichthys molitrix during the 14-day More
        In this project, the effect of salvia officinalis extract coating in three treatments (at concentration of 1, 2, and 3%, respectively) was investigated on chemical and microbiological characteristics of fillets prepared from hypophthalmichthys molitrix during the 14-day refrigeration storage (4 °C) period. On days 1, 4, 7, 10 and 14 of storage, the treatments were chemically analyzed in terms of thiobarbituric acid (TBA) and total volatile base nitrogen (TVB-N), microbial load (total bacterial load) and moisture content, acidity (PH), and water holding capacity (WHC). Based on the obtained results, the amount of TVB-N in all treatments was significantly reduced compared to control treatment (p < 0.05). The increasing trend of bioaburic acid during storage period in all treatments was significantly lower than the control treatment. Considering total bacterial load, all of the coated specimens had significantly lower bacterial load compared to the control group except for the first day. Based on the evaluation results of treatments moisture during the storage period, there was a significant difference in all indices except on day 14. There was also no significant difference between samples with regard to samples WHC. Considering pH, a significant difference was observed in indices on different days between samples except on days 4 and 14. In relation to pressurized water, the obtained data from treatments showed no significant difference except on day 4. Considering that treatment 3 (treatment coated with 3% salvia extract) showed more advantages in most indices compared to other coated treatments, the above mentioned coating was therefore recognized as the best treatment in this study and its application is recommended for effective preservation of the chemical and microbial properties of food products during the storage period. Manuscript profile
      • Open Access Article

        17 - Comparison of the impact of bio-fertilizers on agronomic characteristics, livestock and medicinal Salvia officinalis
        Seyyed Javad Marashi Joseph Niknejad Hormoz Falah Amoli Jaber Mehdiniya Afra2
         In order to study the effect of stimulating the growth of bacteria and other fertilizer (PGPR) on yield and yield components of medicinal plant Salvia in the cloud for factorial in a randomized complete block design, with three replications in a garden of citrus t More
         In order to study the effect of stimulating the growth of bacteria and other fertilizer (PGPR) on yield and yield components of medicinal plant Salvia in the cloud for factorial in a randomized complete block design, with three replications in a garden of citrus trees with a height between 2014, 11 meters above sea level was carried out. The first factor in 3 levels include : manure 3 tons, 6 tons per hectare, the second factor control. 4 level include : Azospirillum, Pseudomonas, Azospirillum and Pseudomonas + control. The use of stimulus effect of bacteria fertilizer and other significant growth on increasing the length of Size Canopy, Height, Root volume, During leaf, Leaf width, has a number of tributaries. The interaction of the biological and organic fertilizer is also the Size Canopy and the Root volume on a subsidiary of a significant positive impact on other traits was having. Based on the results of interaction most the length of the Size Canopy and Height and Root volume, During leaf, Leaf width were tributaries in combination of two bacteria associated with the application of fertilizer average 64.33  cm, 58.40 Cm, 64.73 Ml, 6.86 Cm and 2 Cm respectively, and the lowest amount of 6 tons of these attributes in the mode of not using manure and biological fertilizer was achieved without the use of it average 41 Cm, 35.06 Cm, 25.36 Cm, 25.36 Ml, 4.13 Cm, 1.16 respectively. Manuscript profile