• List of Articles Cyclodextrin

      • Open Access Article

        1 - Low Fat Cream Cheese Fortification Based on β-Cyclodextrin / Inulin Nano Emulsions with Vitamins E and D
        M. Tahery T. Mostaghim
        Introduction: Food fortification is a way to compensate for the lack of micronutrients in society, which is used by all countries in the world to minimize or control the lack of essential nutrients. Meanwhile, the cream cheese is a suitable carrier for fortification due More
        Introduction: Food fortification is a way to compensate for the lack of micronutrients in society, which is used by all countries in the world to minimize or control the lack of essential nutrients. Meanwhile, the cream cheese is a suitable carrier for fortification due to its wide range of uses. The aim of this study was to fortify the low-fat cream cheese based on β-cyclodextrin / inulin nano emulsions with vitamins D and E. Materials and Methods: Nano emulsions were prepared with 400, 450 and 500 units of vitamin E and 5, 10 and 15 micrograms per gram of vitamin D. Free radical scavenging tests (antioxidant activity), trapping rate, release rate and nano emulsions size were evaluated. The cream cheese tests consisted of the assessments regarding percent acidity, fat, moisture contents, textural properties (hardness, adhesion and elasticity) and peroxide index. Sensory characteristics (taste, texture, appearance, aroma and overall acceptance) were assessed by a 5-point Hedonic method. Results: The results showed that by increasing the use of these two vitamins, the morphological properties of nano emulsions changed and their size increased. Trapping rates ranged from 65 to 98% and release rates ranged from 61 to 84%. The results showed that during the storage period of the cheese in the time intervals of production days, fifteenth, thirtieth, forty-fifth and sixtieth day storage, the index of hardness, adhesion, acidity and peroxide number increased significantly (p≥0.05). Moisture content, elasticity index and sensory characteristics decreased significantly (p≥0.05). The fat content of treated cheese did not show significant differences with the control sample (p <0.05). Conclusion: Considering all physicochemical properties as well as the results of sensory evaluation, the treatment with 450 units of vitamin E and 5 micrograms per gram of vitamin D was selected as the optimal treatment. Manuscript profile
      • Open Access Article

        2 - Studying the effect of beta-cyclodextrin natural polymer for improving dyeing condition and reduction of environmental pollution
        akhtar mousavi ahmad akbari seyed kazem mousavi
        Background and Objective: environmental and economic limitations that are imposed dramatically on textile and dyeing industry leads to the development of environmentally friendly processes for modifying the properties of fibers and improving the existing traditional pro More
        Background and Objective: environmental and economic limitations that are imposed dramatically on textile and dyeing industry leads to the development of environmentally friendly processes for modifying the properties of fibers and improving the existing traditional processes. Many efforts have been done for decreasing costs and disposed contaminants which one of them is using natural polymers. The purpose of this study is applying beta-cyclodextrin natural polymer as an appropriate alternative with favorable environmental effects for other chemical additives in dyeing. Material and Methodology: In this study, wool fiber amended/treated by β-Cyclodextrin biocompatible polymer and its dyeing features such as the effect of β-Cyclodextrin composition (%20-0/5), dyeing pH (3-7) and density of the dye (%5-75) on the dyeing capabilities of wool with madder dye color was evaluated and compared. And finally, physical changes of crude fiber and amended fiber after dyeing was amended/treated using SEM analysis. Findings: According to the results, as the β-Cyclodextrin amount increased, the color strength of the samples are considerably enhanced and dye ability (K/S) is better in the case of modified wool rather than aluminium-mordanted wool and pristine wool. Besides, exhaustion of modified wool in neutral pH rather than acidic pH has been increased dramatically while no appreciable changes was observed in pristine wool dye ability with pH changes. Color strength (K/S) data were in the following order of the β-Cyclodextrin modified wool>. Discussion and Conclusions: In general, according to the conditions of modifying wool with β-Cyclodextrin biocompatible polymer and changes in dyeing conditions, not only removing chemical compounds from the wastewater of textile industrial can beapplied, but also the amount of consumed dye and unabsorbed dye remaining in wastewater can be reduced which is environmentally very important. Manuscript profile
      • Open Access Article

        3 - Synthesis and characterization of bifunctional basic mesoporous organosilica catalyst as an efficient and ecofriendly nanocomposite in Biginelli condensation reaction
        Fatemeh Ghalambaz Asadollah Farhadi Ali Reza Kiasat Rashid Badri
      • Open Access Article

        4 - Application of Magnetic Polymer Particles Modified with β–Cyclodextrin for Adsorption of Bovine Serum Albumin
        Mahshid Nikpour Nezhati Habibollah Baharvand Zahra Ghorbani
      • Open Access Article

        5 - Dispersive solid-phase extraction for preconcentration of Amlodipine in aqueous samples using Fe3O4@MWCNT- β cyclodextrin composite
        ali moghimi Mostafa Shojai Milad Abniki
        In this reasearch, innovative techniques to exploit small amount of Amlodipine in solid phase in water sample through Multi Wall Nanotube- NH2 its measurements by visible spectrophotometry and ultra violet in biological samples has been used. These techniques are di pha More
        In this reasearch, innovative techniques to exploit small amount of Amlodipine in solid phase in water sample through Multi Wall Nanotube- NH2 its measurements by visible spectrophotometry and ultra violet in biological samples has been used. These techniques are di phasic system, which donor phases are watery samples and recipient phase is Fe3O4@MWCNT- β cyclodextrin. The experiments have been performed in two extraction stages of Amlodipine watery samples desorption by using Ammonia solvent and desorption samples were put to spectrophotometry device UV-Vis for analysis. This is quick and easy method and is consistent with many of available instrumental techniques. Exploitation parameters such as, desorption organic solvent, donor and recipient pH, extraction time, desorption time, stirring time, donor phase volume and surfactant effect were optimized and quantitative evaluation and measurements were performed in optimal conditions. The mentioned techniques have many advantages such as: short extraction time, consumption of organic solvent, deleting previous experiments effect, low diagnosis level and high-condensed factors and diagnosis level for Amlodipine are 14.5 - (LOD) 7.5 µgL-1 respectively. Linear range.0.02-7.9 mgL-1 and rational standard deviation for Amlodipine were % 1.9 and R2=0.9989. Manuscript profile
      • Open Access Article

        6 - Extraction of trigonelline from plasma using a new magnetic composite through the application of experimental design
        mahdieh Abbasi meymand maryam kazemipour mehdi ansari dogahe Mehdi shahidizandi
        Bentonite-β-cyclodextrin-iron nanoparticles (Ben-βCD-INP) composite was synthesized,characterized, and utilized like an innovative magnetic solid-phase extraction ( MSPE) adsorbent to separate and preconcentrate trigonelline . Experiment conditions to find imp More
        Bentonite-β-cyclodextrin-iron nanoparticles (Ben-βCD-INP) composite was synthesized,characterized, and utilized like an innovative magnetic solid-phase extraction ( MSPE) adsorbent to separate and preconcentrate trigonelline . Experiment conditions to find important variables of trigonelline adsorption on the Ben-βCD-INP were A: time, B: Adsorbent amount, C: pH and for desorption were A: temperature, B: concentration, C: time, and D: Volume .. The adsorbent contributes significantly in the extraction process. The INP in the nano composite makes it easy to remove the adsorbent with the help of a magnet. Scanning electron microscopy( SEM ), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), vibrating sample magnetometry (VSM), and X-ray diffraction (XRD) were used to characterize the synthesized adsorbent. Experimental design was used to optimize the factors affecting extraction. trigonelline in plasma samples was extracted and evaluated by a reversed-phase HPLC–UV method. The findings have shown that MSPE was able to extract trigonelline efficiently. The developed HPLC–UV procedure for the determination of trigonelline in human plasma, showed linear relation shipin the concentration interval of 0.05-10 mg/L (r = 0. 9998) with the limit of detection (LOD), the limit of quantitation (LOQ) and recovery (%) of 0.005, 0.018 mg/L, and 114%, respectively. The procedure was successfully used to determine the concentration of trigonelline in human plasma. This study offers a promising hybrid nano bio material adsorbent in biomedical nanotechnology to selective measurement of the drug or supplements such as trigonelline from plasma. Manuscript profile
      • Open Access Article

        7 - Preparation of cyclodextrin functionalized graphene nanosheets and its application in electrochemical determination of imipramine
        Hossein Dastyar Elham Tavana Farshid Fasihi Seyed Esmaeil Moradi Fatemeh Farjami
        In the present study, a glassy carbon electrode (GCE) modified with cyclodextrin graphene organic-inorganic hybrid nanosheets (CD-GNs) was prepared and applied for the sensitive electrochemical determination of imipramine (IMP). The surface morphology of the proposed el More
        In the present study, a glassy carbon electrode (GCE) modified with cyclodextrin graphene organic-inorganic hybrid nanosheets (CD-GNs) was prepared and applied for the sensitive electrochemical determination of imipramine (IMP). The surface morphology of the proposed electrode was characterized by scanning electron microscopy. Electrochemical results clearly demonstrated that CD-GNs organic-inorganic hybrid nanosheets could exhibit very high supramolecular recognition and enrichment capability. The effect of experimental conditions such as pH and scan rate were also investigated. Using differential pulse voltammetry (DPV), the modified electrode was applied for the sensitive determination of IMP in the range of 0.24-25 µM at pH 7.0. The limit of detection (S/N=3) was 47 nM. The RSD was obtained 1.75% which demonstrated the good repeatability of the fabricated electrode for IMP determination. Cyclic voltammetry (CV) was also used to attain information about the oxidation mechanism and calculating kinetic parameters. The proposed nanocomposite electrode exhibits good applicability for monitoring IMP in pharmaceutical formulations. Manuscript profile
      • Open Access Article

        8 - A brief review on the chemistry of host types in host-guest interactions
        Abdulhamid Dehghani Milad Ghezelsofloo Leila Moradi
        Host-guest nanochemistry is a branch of supramolecular chemistry in which a so-called host molecule binds to a guest molecule or ion. Host-guest interactions involve two molecules or substances that can form complexes through unique structural relationships and non-cova More
        Host-guest nanochemistry is a branch of supramolecular chemistry in which a so-called host molecule binds to a guest molecule or ion. Host-guest interactions involve two molecules or substances that can form complexes through unique structural relationships and non-covalent bonding. Also called molecular recognition, this type of interaction is widely found in biological recognition processes, such as enzyme-inhibitor and antigen-antibody interactions. Host-guest molecular recognition provides a powerful approach to construct a dynamic interface that allows the resulting assemblies to be structurally manipulated in size and shape. Thus, it opens a path to construct smart supramolecular systems with multilevel reactivity. Host-guest nanochemistry incorporates the idea of molecular recognition and interactions through non-covalent bonding. Noncovalent bonding is critical in maintaining the three-dimensional structure of large molecules such as proteins and is involved in many biological processes in which large molecules are specifically but transiently bound together. Host-guest interactions have attracted considerable attention since their discovery, as many biological processes require host-guest interactions and can be useful in some material designs. In this article, the host-guest molecules and some of their applications are briefly introduced. Manuscript profile
      • Open Access Article

        9 - Inclusion Complex of β-CD-DZ as a nanocarrier: Preparation, Spectroscopic characterization, Thermodynamic parameters and molecular modelling Study
        Fatemeh Fateminasab Abdol-Khalegh Bordbar
      • Open Access Article

        10 - Evaluation of Photosynthetic Activity, Carbohydrates, Proline and Essential Oils (Ocimum basilicum L.) under the Elicitor of β-Cyclodextrin Nanoparticles
        Azadeh Loni Sara Saadatmand Hossien Lari Yazdi Alireza Iranbakhsh
        Induction of engineered nanoparticles into medicinal plants causes resistance, enhances quantitative and qualitative performance and effective substances in them. In this study, β-cyclodextrin nanoparticles (β-CDNPS) were synthesized. The nanoparticle profile More
        Induction of engineered nanoparticles into medicinal plants causes resistance, enhances quantitative and qualitative performance and effective substances in them. In this study, β-cyclodextrin nanoparticles (β-CDNPS) were synthesized. The nanoparticle profile was determined by UV-VIS spectrum, transmission electron microscopy (TEM) and dynamic light scattering (DLS). Then different concentrations of β-CDNPs including 0, 10, 50, 100 mg / l were used for foliar spray of basil (Ocimum basilicumc.v. Keshkeni luvelou). The amount of chlorophyll pigments and basil essential oil was significantly different (P≤ 5%) compared to the control.The maximum amount of chlorophyll b was observed in 100ppm treatment. The results showed a significant reduction (P≤5%) of the minimum fluorescence value (Fo) in the treatment of 50 ppm compared to the control and two levels of 10 and 100 ppm of β-CDNPS. The level of 50 ppm significantly increased (P≤ 5%) the maximum fluorescence, variable fluorescence (Fv), photochemical efficiency of the photosystem compared to the control. Foliar spray of β-CDNPS caused changes in basil gas exchange. Soluble sugars and proline of basil leave and root in 50ppm treatment had a significant increase (P≤%5) compared to the control, so that insoluble sugars in leave and root showed the opposite trend. In the presence of β-CDNPS, phenylpropanoids and terpenoids concentration, in the basil showed a significant difference (P≤5%) compared to the control group. Induction of β-CDNPS nanoparticles in the biosynthesis pathway of secondary metabolites results in plant productivity Basil plant under the treatment of nano β-cyclodextrin, with concentration-dependent behavior increased yield per unit area. Therefore, foliar spray at the right concentration can act as an inducer while stimulating, preserving the active ingredients in basil and increase the content of essential oil for food and drug consumption. Manuscript profile
      • Open Access Article

        11 - Effects of centrifugation and cholesterol-loaded with cyclodextrin in the soybean lecithin -based extender on the quality of the post-thaw sperm of Ghezel ram
        Mohammad Shamsolahi Hossein Daghigh Kia
        When using frozen-thawed semen, maintaining the motility and viability of ram sperm is important for achieving high pregnancy rates. The goal of this research was to clearly elucidate the effects of centrifugation and cholesterol-loaded cyclodextrin (CLC) in a soy lecit More
        When using frozen-thawed semen, maintaining the motility and viability of ram sperm is important for achieving high pregnancy rates. The goal of this research was to clearly elucidate the effects of centrifugation and cholesterol-loaded cyclodextrin (CLC) in a soy lecithin-based extender on post-thaw ram sperm quality. Sperm samples were collected from 5 Ghezel rams with the age of 4-5 years for 3 weeks. After the initial assessment, the approved semen samples were combined and divided into 8 equal parts. Four samples were combined at 30˚C and the seminal plasma was then removed by centrifugation. The semen from the other four samples was not centrifuged and was diluted with Tris buffer plus different concentrations of CLC (0, 0.75, 1.5 and 3 mg/ 1.2×108 spermatozoa) and 7% glycerol, similar to the first group. The samples were then cooled to 5˚C and frozen in 0.25 ml straws. After thawing, total motility (TM) and progressive motility (PM), straight line velocity (VSL), curvilinear velocity (VCL), beat cross frequency (BCF), total antioxidant capacity (TAC), superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase (GPX), the integrity of the acrosome membrane and the integrity of the plasma membrane were significantly (p < /em><0.05) higher in the 1.5 mg CLC group compared to the other groups. Also TM, PM, VCL, TAC, SOD, GPX and plasma membrane was significantly (p < /em><0.05) higher in the group without centrifugation than in the centrifugation group. Overall, the results suggested that addition of 1.5 mg CLC improves most of the sperm parameters measured in vitro in comparison to other groups. Manuscript profile
      • Open Access Article

        12 - Effect of different concentrations of beta-cyclodextrin nanoparticles on growth indexes and enzymatic defense systems, Ion leakage and amount of membrane lipid peroxidation in basil medicinal plant (Ocimum basilicum L. c.v. keshkeni luvelou)
        azadeh loni Sara Saadatmand Hossein Lari Yazdi Alireza Iranbakhsh
        By nanotechnology entrance into the field of medicinal plants, the agricultural industry and food industry ensures an increase in the amount and quality of their products, along with the preservation of the environment. The properties of materials are changed by changin More
        By nanotechnology entrance into the field of medicinal plants, the agricultural industry and food industry ensures an increase in the amount and quality of their products, along with the preservation of the environment. The properties of materials are changed by changing their size to nano. The use of beta-cyclodextrin nanoparticles is described as a new protection strategy of the plant and induces a plant defense response. For this purpose, to study the effect of beta-cyclodextrin nanoparticles on the physiologic indexes and biochemical activities in basil of keshkeni luvelou cultivar, an experiment was performed based on a completely randomized design with four replications at four levels of 0.10, 50, 100mg/l in the greenhouse. The results showed that different growth indices such as root and stem length and diameter, fresh and dry weight of roots, shoots, and leaf area increased by 5% compared to the control and the highest increase was reported at 50ppm. Data analysis showed that the effect of different treatments on the activity of superoxide dismutase and catalase, peroxidase enzymes, malondialdehyde content, and ion leakage of roots and leaves were significantly increased (P≤5%) compared to the control. Membrane stability index was assessed by measuring the electrolyte leakage of leaves and roots. A significant reduction (P≤5%) of ion leakage and malondialdehyde of roots and leaves was observed in the treatment of 50mg/l nano-beta cyclodextrin which indicates an increase in enzyme activity. With the entrance of nanoparticles into agriculture can minimize the scope of chemical control and disruption of environmental physiological practices. The trend of changes in physiological and biochemical parameters studied in the present study are relatively reliable indicators to introduce the best concentration of beta-cyclodextrin nanoparticles for basil. Manuscript profile
      • Open Access Article

        13 - β-Cyclodextrin conjugated imidazolium cation: A neutral, eco-friendly and water-miscible dicationic ionic liquid in the regioselective ring opening of epoxides
        Fatemeh Moheiseni Ali Reza Kiasat
      • Open Access Article

        14 - Studies on inclusion complexes of 2-[Substituted arylideamino]-1, 3, 4-thiadiazino [6,5b]indole with β- Cyclodextrin
        Sunakar Panda Jagat Tripathy
      • Open Access Article

        15 - Thermodynamic, spectral and antimicrobial activity of inclusion complexes of acridone and its oxime with β-cyclodextrin
        Swapna Sankar Nayak Sunakar Panda
      • Open Access Article

        16 - Evaluation of different methods of extraction and micropropagation of lemon grass on physicochemical properties of the extract
        Sanaz Kamel Abdollah Alizadeh dariush khademi Shurmasti
        This research was conducted to evaluate the extraction methods and also the encapsulation of lemon grass extract on the efficiency of extraction of effective components and some physical properties of the extract. Extraction was done by Soxhlet and ultrasonic methods. T More
        This research was conducted to evaluate the extraction methods and also the encapsulation of lemon grass extract on the efficiency of extraction of effective components and some physical properties of the extract. Extraction was done by Soxhlet and ultrasonic methods. The extracts were encapsulated using solutions of wall materials including cyclodextrin and sodium caseinate. The extraction efficiency of the extract was measured and compared in two methods. The results showed that ultrasonic extraction significantly increased the extraction efficiency of citronellol, eugenol, linalool, and betacaryophyllin B compared to the Soxhlet method (p<0.05). Encapsulation of the extract with sodium caseinate compared to beta-cyclodextrin increases the production efficiency of microencapsulation (85.7 vs. 84%), increases moisture content (4.86 vs. 3.9%) and decreases mass density (250.21 vs. 547 kg/ M3) (p<0.05). The score of the sensory properties of lemon grass extract, including colour, smell and taste, was higher in the ultrasound method than in the Soxhlet method, and in sodium caseinate microcapsules, it was higher than beta-cyclodextrin. In general, ultrasonic extraction increased the efficiency of extracting effective substances and coating with sodium caseinate improved the physical and sensory properties of lemon grass extract. Therefore, it is recommended to extract lemon grass by ultrasonic method and cover the extracted extract with sodium caseinate to improve its use in food, cosmetic and medical industries. Manuscript profile