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Open Access Article
1 - The Effect of Combined Training and Caffeine Supplementation on Toll-like Receptor 2 (TLR2), TLR4, and Dectin-1 in Obese Men
SH. Ghaderi Goodarzi A. Abbassi Daloii A. Abdi A. SaeidiIntroduction: Overweight and obesity are associated with increased inflammatory conditions and metabolic disorders. A therapeutic agent that can suppress metabolic and immune disorders may effectively ameliorate parallel abnormalities in obesity. The aim of this study w MoreIntroduction: Overweight and obesity are associated with increased inflammatory conditions and metabolic disorders. A therapeutic agent that can suppress metabolic and immune disorders may effectively ameliorate parallel abnormalities in obesity. The aim of this study was to evaluate the effect of combined training and caffeine supplementation on Toll-like receptor 2 (TLR2), TLR4, and dectin-1 in obese men. Materials and Methods: In a semi-experimental trial, 44 obese men were purposefully and accessibly selected and randomly divided into four groups: 1) control, 2) combined training, 3) caffeine and 4) combined training -caffeine. Subjects received 6 mg of caffeine per kilogram of body weight daily for 12 weeks. The combined training program include circular resistance training (3 times with 14 repetitions at 50% of one maximum repetition and 30 seconds rest between each station) and aerobic exercise (70% maximum heart rate for 30 minutes) was performed 3 sessions per week for 12 weeks. The combined training program was performed for 12 weeks and 3 sessions per week. Data were analyzed with covariance analysis and Tukey post hoc test at the p<0.05.Results: The results showed that 12 weeks of combined training, caffeine and combined training - caffeine significantly reduced serum levels of TLR2, TLR4 and Dectin-1 (P=0.001). The reduce of serum levels of TLR2, TLR4 and Dectin-1 were significant in the combined training compared to caffeine group (P=0.001). the effect of interactive combined training with caffeine was more than supplementation and training alone.Conclusion: According to the findings, it is suggested that combined training intervention with caffeine consumption be used in order to reduce its inflammatory effects associated with obesity. Manuscript profile -
Open Access Article
2 - Effect of endurance, resistance and combined trainings on glycemic control and lipid profile of type2 diabetic patients
Farzad Khosravi Zahra Rahimi -
Open Access Article
3 - Effects of 8 weeks combined resistance and endurance training on A-FABP in obese middle age men
Ehsan Bahrami Abdehgah Najmeh Abdollahpur Fariba Hosseini -
Open Access Article
4 - An Investigation into Irisin Levels: Acute and Chronic Effects of Combined Training and Its Association with Anthropometric Variables in Overweight Men
Yazgaldi Nazari Masoud Nikbakht Abdolhamid Habibi -
Open Access Article
5 - The Effect of Combined Rehabilitation Training on Plasma Levels and Ghrelin Gene Expression in PBMNC Among CABG Patients
Artemis Naghibzade amir rashidlamir Rambod Khajeie Mahdi Zarei Akbar Safipour afsharRehabilitation training in cardiac patients after coronary artery bypass graft (CABG) improves several physiological capacities. The aim of this study was to investigate the effect of eight weeks of combined training on plasma levels and ghrelin gene expression in PBMNC MoreRehabilitation training in cardiac patients after coronary artery bypass graft (CABG) improves several physiological capacities. The aim of this study was to investigate the effect of eight weeks of combined training on plasma levels and ghrelin gene expression in PBMNC among CABG patients. In this quasi-experimental study, 30 cardiac patients of Javad Al-Aemeh cardiac specialty hospital of Mashhad, who underwent CABG operation, were selected using convenience and purposeful sampling method and randomly divided into two equal groups (n=15): combined training and control. The combined training group performed selected aerobic and resistance training protocols for eight weeks, three sessions per week. Before and after training program, body composition assessments and blood sampling were performed to measure variables. Then, the obtained data were analyzed using independent and dependent t-tests at the significance level of 0.05. Data analysis showed that combined training significantly reduces body weight and BMI and significantly increases plasma ghrelin levels and relative expression of ghrelin gene in PBMNC (P≤0.05). Additionally, a significant difference was observed between plasma ghrelin levels and relative expression of ghrelin gene in PBMNC of training group compared to control group (P≤0.05). It seems that eight weeks of combined rehabilitation training increases plasma levels and ghrelin gene expression in PBMNC among CABG patients and can promote desirable physiological adaptations in cardiovascular health. Manuscript profile -
Open Access Article
6 - Investigating The Effect of Cardiac Rebalitation Program Based on Combined Training on VEGF Gene Expression in ACS Patients with CABG
Seyed Emad Alavinia Amir Rashidlamir Rambod Khajei Amene Barjasteh YazdiCardiovascular diseases are the leading causes of mortality and death in all areas of the world except Africa. This study aimed at the effect of eight-week combined training on Endostatin and VEGF gene expression in CABG patients.This is an applied and semi-experimental MoreCardiovascular diseases are the leading causes of mortality and death in all areas of the world except Africa. This study aimed at the effect of eight-week combined training on Endostatin and VEGF gene expression in CABG patients.This is an applied and semi-experimental research with two groups (interventional and control), which was conducted as a pretest and posttest. 30 middle-aged CABG men were selected using purposive sampling based on inclusion criteria. Participants were randomly divided into two groups of control and combined training. Quantitative Real-time PCR was utilized to measure Endostatin and VEGF gene expression levels. The eight-week combined exercise training was conducted in three sessions per a week. Dependent t-test and independent t-test were used to data analysis. A significant increase was observed after eight weeks of combined training on VEGF gene expression in CABG patients. (p=0.001), but it was not Significant on Endostatin gene expression( p=0.38) . Eight weeks of combined Cardiac Rehabilitation training as the protocol used in this research increased the expression of the VEGF gene in CABG patients , but there were not any significant changes on Endostatin gene expression by this way. As a result, the increase in the VEGF gene is one of the results of adaptation to the combined exercise activity used in this study, and it appears that physical activity is an important and effective factor in the process of angiogenesis, and can play a key role in the prevention of cardiovascular diseases. Manuscript profile -
Open Access Article
7 - The Effect of Interval Training and Two Types of Combined Exercises on the Level of Angiopoietin 1 and 2 in Patients During the Rehabilitation Period after Cardiac Surgery (CABG)
Mahdi Mokari Ali Akbar Nezhad Mostafa NejatianDue to the complications caused by surgery, especially involuntary immobility, patients' ability to function is significantly reduced after surgery, so participation in exercise and rehabilitation programs is recommended to patients. The aim of this study was to investi MoreDue to the complications caused by surgery, especially involuntary immobility, patients' ability to function is significantly reduced after surgery, so participation in exercise and rehabilitation programs is recommended to patients. The aim of this study was to investigate the effect of interval training and two types of combination on angiopoietin 1, 2 levels in patients in the postoperative rehabilitation period (CABG). A total of 30 cardiac patients operated on in Tehran Heart Center were selected by simple random sampling and randomly divided into three groups (10 patients in each group): interval training, interval training-resistance and continuous-resistance. Exercises were performed for 6 weeks and 3 sessions per week. Interval training were performed from the first to the sixth week with an intensity of 60 to 80% of the maximum heart rate. Continuous exercises were performed from 10 to 20 minutes of activity with an intensity of 60 to 70% of the maximum heart rate. Resistance training included four movements of the upper chest, biceps flexion, thigh extension, and inside the thigh. 2 sets of 10-12 repetitions with an intensity of 50-70% of the maximum repetition were performed from the first to the sixth week. Blood samples were taken 48 and 24 hours before and after the training protocols and the expression of angiopoietin 1, 2 genes was measured by real-time-PCR. The results within the group indicate that there is a significant difference between the pre-test and post-test of angiopoietin 1, 2 in all groups (p ≤ 0.05). Also, comparison of intergroup results in angiopoietin variable 1 and 2 showed that there was no significant difference between training groups in the post-test stage (p ≥ 0.05). All three training methods were able to improve the expression of the studied genes, to make favorable changes in reducing the consequences of heart tissue damage. Manuscript profile -
Open Access Article
8 - Effect of Eight Weeks of Combined aerobic-resistance Training on Sleep Quality, Prolactin Hormone, and Growth Hormone, of Overweight and obese adolescent girls
Zohreh Nikjoo mona Mehdizadeh Haghighi Anahita Shabani Nasibeh Ezeddin Mahtab DehghanzadehPurpose: The purpose of this study was to determine the effect of eight weeks of combined training (aerobic-resistance) on sleep quality, prolactin hormone and growth hormone, of overweight and obese adolescent girls. Research method: The current research was of a semi MorePurpose: The purpose of this study was to determine the effect of eight weeks of combined training (aerobic-resistance) on sleep quality, prolactin hormone and growth hormone, of overweight and obese adolescent girls. Research method: The current research was of a semi-experimental type. In this study, 30 overweight and obese adolescent girls were randomly divided into two experimental groups of 15 people (average age: 16.33 ± 0.97 years; body mass index: 26 30.48±3 kg/m2) and the control group (mean age: 16.53±1.18 years; body mass index: 30.48±3.26 kg/m2) were divided. Eight weeks experimental group they performed progressive aerobic-resistance exercises three sessions a week. Each session consists of 10 minutes of warming up, 5 minutes of cooling down, 30 minutes of aerobic exercise with an intensity of 60-80% of the maximum heart rate and 45 minutes of resistance exercise with an intensity of 50-70%. Repetition was the maximum. Before and after eight weeks of training, sleep quality, anxiety level and prolactin and growth hormones were measured. Statistical information was obtained by one-way ANCOVA and Yeoman-Whitney tests through spss software. 22 cases were analyzed. A significance level of p0.05). Conclusion: A combined training course (aerobic-resistance) probably improves the quality of sleep of overweight and obese students and has no effect on prolactin and growth hormone levels Keyword: sleep quality, prolactin hormone, growth hormone, combined training (aerobic-resistance). Manuscript profile
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