• List of Articles Cholestrol

      • Open Access Article

        1 - Effect of Lead on Some Biochemical Indices of Farmed Silver Carp (Hypophthalmichthys molitrix)
        M. Shakoori A. Abdali
        The aim of this study was to evaluate the toxicity effect of lead heavy metal on some serological parameters on Silver Carp in the vicinity with lead for a short term. In order to do this study a total of 135 fish with mean weight of 50±10 gand mean length of 13& More
        The aim of this study was to evaluate the toxicity effect of lead heavy metal on some serological parameters on Silver Carp in the vicinity with lead for a short term. In order to do this study a total of 135 fish with mean weight of 50±10 gand mean length of 13±1 cm were placed in adjacent to 0, 5 and 10 mg/l of Pb (NO3 )2 in 9 aquariums of 90 liter capacity.Sampling was done randomly each 12 hours for 96 hours from caudal vein of the fishes. The results showed that there was a significant difference in the amount of hemoglobin in 24 hours, between the control and treatments. The level of glucose was increased significantly by increasing the concentration of lead and passing of the time. The levels of triglyceride and albumin did not change significantly (P>0/05). The level of cholesterol increased significantly until 72 hours and after that decreased significantly. Amount of total protein increased significantly by increasing the concentration of lead and time. Based on the results, biochemical parameters are useful for monitoring of lead acute toxicity in Silver Carp. Manuscript profile
      • Open Access Article

        2 - Physiological and Histological Studies of Obesity Inducing a High Fat – Diet in Adult NMRI Strain Mice
        فرناز بناکار کاظم پریور پریچهر یغمایی هما محسنی کوچصفهانی
        Obesity is a major health concern worldwide against which development of new strategies is warranted. Animal models are a valuable tool in these studies and could be developed using a simple and cost effective diet in susceptible strains. Adult NMRI mice weighing 25andp More
        Obesity is a major health concern worldwide against which development of new strategies is warranted. Animal models are a valuable tool in these studies and could be developed using a simple and cost effective diet in susceptible strains. Adult NMRI mice weighing 25andplusmn;4 g were fed by a high fat diet for six weeks (E group) in comparison with a control group(C) receiving standard chow. Weekly measurements of body weight were performed. Animals were sacrificed after six weeks, and abdominal fat amount, fat liver accumulation, and LDL-C, HDL-C, cholesterol and triglyceride were measured. Histological studies were done on kidney, liver and testis. Body weight of E group increased up to about 50% (1.25-fold more than C group), their abdominal fat amount showed a two-fold increase compared with the C group(pandlt;0.001), and morphologic differences were observed in liver tissue relative to fat accumulation. Of biochemical factors, only triglyceride levels showed statistically significant increase in the E group (pandlt;0.05). Microscopic assessment of kidney, liver and testis samples, regarding to cells size and number showed no significant differences between C and E groups. This method is proposed as a mean to simulate an early stage of obesity. Manuscript profile
      • Open Access Article

        3 - Evaluation of hyperlipidemia in patient with hypertension refered to hospitals of Azad university of Mashhad in 86-87
        Mahdi Masumian Mohamad Sarafraz yazdi Golnoosh Ghooshchi
        Aims: About a quarter of adult people (60 million in USA and 1 billion all over the world) suffer arterial blood pressure. Hypertension is the main reason of mortality around the world and is a big trouble in public health. Whereas the lipids such as total cholesterol, More
        Aims: About a quarter of adult people (60 million in USA and 1 billion all over the world) suffer arterial blood pressure. Hypertension is the main reason of mortality around the world and is a big trouble in public health. Whereas the lipids such as total cholesterol, triglyceride, HDL and LDL concern in atherosclerosis which are followed by cardiovascular disorders, we conducted to evaluation of hyperlipidemia in the high arterial blood pressure patients. Method: We carried out our thesis by observational case-control method and we studied 400 patients who refer to the cardiac and internal clinics of Azad University Hospitals of Mashhad during 2007-2008. We divided the patients to 2 groups: 200 patients for control (with normal blood pressure) and 200 patients for case group (high blood pressure). We recorded clinical and demographic information by a questionnaire and then a lipid profile test (cholesterol, triglyceride, HDL and LDL) was done. Results: According to the results there is a significant difference in the levels of total cholesterol and triglyceride between 2 groups (Pvalue= 0.0001). But there is not a significant difference for HDL (Pvalue= 0.692).A bout LDL there is a significant difference between 2 groups. (Pvalue= 0.001). Due to ‍confounding factors such as age, occupation and etc there is no significant difference in a multi-variable logistic regression model in all lipids except triglyceride between 2 groups.(total cholesterol (Pvalue= 0.240), triglyceride (Pvalue= 0.027) , LDL(Pvalue= 0.249), HDL (Pvalue= 0.906)). Discussion: Statistical results showed that there is a significant relation between hypertrigliceridemia and hypertension, but other lipids with notice to confounding factors need to accompariment other risk factors until can be predisposal factors for hypertension.   Manuscript profile
      • Open Access Article

        4 - Effect of Probiotic (Protexin) on performance, blood biochemical parameters and egg quality in laying hens
        Ali Reza Safamehr Ali Nobakht
        The effect of probiotic on egg production, egg quality, yolk cholesterol, triglyceride and blood biochemical parameters of layer hens was studied. Experiment was carried out with 256 bird and each sixteen bird were considered as a replicate that were randomly allotted t More
        The effect of probiotic on egg production, egg quality, yolk cholesterol, triglyceride and blood biochemical parameters of layer hens was studied. Experiment was carried out with 256 bird and each sixteen bird were considered as a replicate that were randomly allotted to basal with Probiotic supplementation at rates of 25, 50 and 75 mg/ kg diets. Treatments were arranged in a completely randomized design. The Probiotic used in the study was a commercial preparation (Protexin) with 3&times; 10<sup>9</sup> spore g-1 of the product. Egg production, egg weight, feed intake, feed conversion ratio and egg mass were not influenced by Probiotic, as well as Haug unit, specific gravity, egg shell weight, egg shell thickness and shell weight/ surface area. Experimental groups had not statistical differences in biochemical parameters such as albumin, total protein, phosphorus, calcium, cholesterol, triglyceride and glucose amounts. Probiotic had not also any effect on egg yolk cholesterol and triglyceride. It was concluded that dietary Probiotic supplementation up to 75 mg/kg of diet had not beneficial effects on the performance and egg quality of laying hens. Manuscript profile