Evaluation of hyperlipidemia in patient with hypertension refered to hospitals of Azad university of Mashhad in 86-87

Subject Areas : علوم پزشکی

Mahdi Masumian ¹ , Mohamad Sarafraz yazdi ² , Golnoosh Ghooshchi ³

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Received: 2017-04-05 Accepted : 2017-04-05 Published : 2016-05-21

Keywords: Hyperlipidemia, Hypercholestrolemia, Hypertrigliceridemia- Hypertension, LDL, HDL,

Abstract :

Aims: About a quarter of adult people (60 million in USA and 1 billion all over the world) suffer arterial blood pressure. Hypertension is the main reason of mortality around the world and is a big trouble in public health. Whereas the lipids such as total cholesterol, triglyceride, HDL and LDL concern in atherosclerosis which are followed by cardiovascular disorders, we conducted to evaluation of hyperlipidemia in the high arterial blood pressure patients. Method: We carried out our thesis by observational case-control method and we studied 400 patients who refer to the cardiac and internal clinics of Azad University Hospitals of Mashhad during 2007-2008. We divided the patients to 2 groups: 200 patients for control (with normal blood pressure) and 200 patients for case group (high blood pressure). We recorded clinical and demographic information by a questionnaire and then a lipid profile test (cholesterol, triglyceride, HDL and LDL) was done. Results: According to the results there is a significant difference in the levels of total cholesterol and triglyceride between 2 groups (Pvalue= 0.0001). But there is not a significant difference for HDL (Pvalue= 0.692).A bout LDL there is a significant difference between 2 groups. (Pvalue= 0.001). Due to ‍confounding factors such as age, occupation and etc there is no significant difference in a multi-variable logistic regression model in all lipids except triglyceride between 2 groups.(total cholesterol (Pvalue= 0.240), triglyceride (Pvalue= 0.027) , LDL(Pvalue= 0.249), HDL (Pvalue= 0.906)). Discussion: Statistical results showed that there is a significant relation between hypertrigliceridemia and hypertension, but other lipids with notice to confounding factors need to accompariment other risk factors until can be predisposal factors for hypertension.  

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