The purpose of this study is to compare the effect of four weeks of high-intensity interval training with different volumes on IL-6, TNF-α and hs-CRP in overweight and obese young girls. 24 girls (BMI>25 kg/m) were randomly placed in three groups: HIIT1 group ( More
The purpose of this study is to compare the effect of four weeks of high-intensity interval training with different volumes on IL-6, TNF-α and hs-CRP in overweight and obese young girls. 24 girls (BMI>25 kg/m) were randomly placed in three groups: HIIT1 group (n=8), HIIT2 group (n=8) and control group (n=8). HIIT1 group performed four sets of 30 seconds of running with an intensity of 19-20 RPE, two minutes of rest between sets in each session. HIIT2 group performed four sets of 60 seconds of running with the same intensity and four minutes of rest between sets. training was performed three sessions a week for four weeks. Blood samples were evaluated to measure serum levels of IL-6, TNF-α and hs-CRP 48 hours before and 48 hours after training. To analyze the data . Mixed analysis of variance (ANOVA) test was used at a significant level (P<0.05). hs-CRP level significantly increased only in the HIIT2 group (p<0.05). No significant difference was observed between the groups (p=0.377). The IL-6 significantly decreased only in the HIIT2 group (p<0.05). A significant difference was observed only between the HIIT2 group and the control group (p=0.031). The mean of TNF-α showed a significant decrease only in the HIIT2 group (p<0.05). a significant difference was observed between the HIIT2 group and the control group (p=0.042). It seems that medium-term HIIT training reduces inflammatory indicators (IL-6, TNF-α) compared to short-term and probably has a role in reducing the incidence of heart and metabolic diseases in these people.
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Background and Aim: Previous studies have shown the positive effect of aerobic exercise and curcumin on various variables in diabetes. Also, the combination of these interventions may have a synergistic effect on research variables. The present study investigates the in More
Background and Aim: Previous studies have shown the positive effect of aerobic exercise and curcumin on various variables in diabetes. Also, the combination of these interventions may have a synergistic effect on research variables. The present study investigates the independent and combined effect of aerobic exercise and curcumin supplementation on plasma C-reactive protein concentration in diabetic rats.Methods: Forty male rats were equally divided into healthy control, diabetic control, diabetic exercise, diabetic curcumin and diabetic curcumin + exercise. Aerobic exercise (five sessions / week, each session 30 minutes at a speed of 22 meters / minute, slope: five percent) and supplementation (30 mg / kg body weight, three days / week) were performed for eight weeks. Rats were sacrificed 48 hours after receiving the last intervention.Results: Diabetes increased the concentration of plasma C-reactive protein (P = 0.001). Exercise decreased plasma C-reactive protein concentration (P = 0.001) in diabetic rats. Curcumin also reduced plasma C-reactive protein (P = 0.001) in diabetic rats. The combination of exercise and supplementation had a greater effect on reducing the plasma C-reactive protein concentration than mono / supplementation alone (P <0.001).Conclusion: Exercise and curcumin separately reduced plasma C-reactive protein concentration in diabetic rats. It also seems that the use of a combination of exercise and curcumin than the use of each alone, has been more effective on the variables of the present study.
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Cardiovascular disease, which includes atherosclerosis, is one of the major diseases in the world. High sensitive C-reactive protein is the most sensitive inflammatory marker that recently its serum level predicts risk of cardiovascular disease is suggested. Both garlic More
Cardiovascular disease, which includes atherosclerosis, is one of the major diseases in the world. High sensitive C-reactive protein is the most sensitive inflammatory marker that recently its serum level predicts risk of cardiovascular disease is suggested. Both garlic (Allium sativum) and lemon (citrus limon) are used in the traditional management of CVD without a scientific evidence of the benefit of their combination. This study designed to investigate the hypolipidemic and anti-inflammatory effects of combined extracts of A. sativum and C. limon in male Wistar rats after high-fat diet for eight weeks. For this purpose, 42 adult male rats of Wistar strain, with weights between 200 and 250 gr, were divided into six groups (n=7). Group control and Exp3 was fed on normal pellet diet while group control fat, Sham, Exp1 and Exp2 fed on high-fat diet for up to 8 wk. The combined extract was administered to rats in graded doses for 4 wk and blood serum was analyzed for C-reactive protein and total cholesterol.Results are expressed as means ± SE. Significance differences of biochemical measurements were analyzed by using repeated measure and ANOVA tests to identify differences in phases and among groups. When appropriate, a Tukey posthoc was applied. Statistical significance was accepted at PA. sativum and C. limon was recognizable. However, future long-term well-designed investigations would provide valuable information to establish public health recommendations on the combined extract, taking into account both the nature of the compounds and the optimal dose, for cardiovascular health protection
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