The effect of four weeks of high-intensity interval training with different volumes on IL-6, TNF-α and hs-CRP in overweight and obese young girls.

Subject Areas : Physical Activity and Health

rasoul dokhtabdiyan ¹ , azizeh ahmadi ²

1 - PhD in Sports Physiology, Faculty of Physical Education and Sports Sciences, University of Tehran, Tehran, Iran
2 - PhD in Sports Physiology, Faculty of Physical Education and Sports Sciences, Tabriz University, Tabriz, Iran

Received: 2023-02-10 Accepted : 2023-05-13 Published : 2023-04-21

Keywords: high-sensitivity C-reactive protein (hs-CRP), high-intensity interval training (HIIT), overweight and obese young girls, interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α),

Abstract :

The purpose of this study is to compare the effect of four weeks of high-intensity interval training with different volumes on IL-6, TNF-α and hs-CRP in overweight and obese young girls. 24 girls (BMI>25 kg/m) were randomly placed in three groups: HIIT1 group (n=8), HIIT2 group (n=8) and control group (n=8). HIIT1 group performed four sets of 30 seconds of running with an intensity of 19-20 RPE, two minutes of rest between sets in each session. HIIT2 group performed four sets of 60 seconds of running with the same intensity and four minutes of rest between sets. training was performed three sessions a week for four weeks. Blood samples were evaluated to measure serum levels of IL-6, TNF-α and hs-CRP 48 hours before and 48 hours after training. To analyze the data . Mixed analysis of variance (ANOVA) test was used at a significant level (P<0.05). hs-CRP level significantly increased only in the HIIT2 group (p<0.05). No significant difference was observed between the groups (p=0.377). The IL-6 significantly decreased only in the HIIT2 group (p<0.05). A significant difference was observed only between the HIIT2 group and the control group (p=0.031). The mean of TNF-α showed a significant decrease only in the HIIT2 group (p<0.05). a significant difference was observed between the HIIT2 group and the control group (p=0.042). It seems that medium-term HIIT training reduces inflammatory indicators (IL-6, TNF-α) compared to short-term and probably has a role in reducing the incidence of heart and metabolic diseases in these people.