List of Articles Biocompatibility

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  1 - Investigation of Dental Implant’s Titanium Surface Hydrophilicity Effect on Biocompatibility and Osseointegration
  B Mohammadi A. G Dezfuli E Anbarzadeh A. A Malek Altejari
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  2 - Synthesis and characterization of magnesium-based metal-organic frameworks and investigating the effect of coordination solvent on their biocompatibility
  Saeed Reza Hormozi Jangi
  In this contribution, magnesium-based metal-organic frameworks (average size, 430 nm) were synthesized by a simple, low-cost, and high-efficient method utilizing different coordination solvents. The as-synthesized frameworks were then characterized by several characteri More

  In this contribution, magnesium-based metal-organic frameworks (average size, 430 nm) were synthesized by a simple, low-cost, and high-efficient method utilizing different coordination solvents. The as-synthesized frameworks were then characterized by several characterization methods. The formation of metal-organic framework(MOF( coordination bindings was confirmed by FT-IR, EDX, UV-Vis, and SEM analyses. The organic content of the as-prepared MOFs was quantified by elemental analysis. The results showed that the coordination yield in protic solvents is higher than that of the aprotic solvents. In contrast, the organic content of the MOFs prepared in aprotic media was found to be more than that of the protic solvent due to the competitive role of aprotic solvents in the coordination process. The effect of coordination solvent on the biocompatibility of as-synthesized MOFs was also investigated using the standard protein absorption-desorption and hemolysis analysis. The protein adsorption results showed that the as-synthesized MOFs with protic solvents absorbed about 0.02 μg μg-1, which is 17.5-fold lower than that of the aprotic solvents. The hemolysis ratio of the synthesized sample in protic solvent was calculated at about 0.3%, which is 5 times lower than the hemolysis ratio of the synthetic sample in aprotic media, indicating their high erythrocyte compatibility. These findings reveal that the biocompatibility of magnesium-based metal-organic frameworks is significantly affected by the coordination solvent. The Authors strongly recommend using the results of this contribution for the synthesis of biocompatible carriers for drug and enzyme immobilization aims. Manuscript profile
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  3 - The liquid environment effect on photoluminescence properties of carbon nanoparticles prepared by laser ablation method in liquids with possible biocompatibility applications
  Rasoul Malekfar Samad Moemen Bellah Fatemeh Kazemizadeh
  10.30495/ijbbe.2023.703605
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  4 - Study on compressive and compatibility properties of titanium functionally graded scaffolds (FGSs) as bone replacements
  Esmaeil Shahimoridi Seyed Mohammad Kalantari Arman Molaei
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  5 - Effect of Fluoride Coating on the Degradation of Mg-Based Alloy Containing Calcium for Biomedical Applications
  Abouzar Rezaei-Baravati Masoud Kasiri-Asgarani Hamid Reza Bakhsheshi-Rad Mahdi Omidi Ebrahim Karamian
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  6 - Evaluation of methylcellulose role in thermosensitive hydrogel structure as injectable system for tissue engineering application: fabrication and characterization
  Sogol Motalebi Tala Tapeh Mazyar Sharifzadeh Baei Saeed Heydari Keshel
  One of the challenges in tissue engineering is polymer material selection and design of a suitable structure for hydrogels. In this study, N-isopropylacrylamide/Acrylic acid/N-Acryloxysuccinicimide/2-Hydroxyethyl methacrylate-poly lactide hydrogel  (NIPAAm/AAC/NAS/ More

  One of the challenges in tissue engineering is polymer material selection and design of a suitable structure for hydrogels. In this study, N-isopropylacrylamide/Acrylic acid/N-Acryloxysuccinicimide/2-Hydroxyethyl methacrylate-poly lactide hydrogel  (NIPAAm/AAC/NAS/HEMAPLA) was prepared with various molar ratio by ring-opening polymerization method to fabricate hydrogel substrate with properties of injectability, thermosensitive, physical and mechanical similar of soft tissues. The hydrogel with the ratio of 80/5/5/10 was selected as ideal groups (group 1). Methylcellulose was also used in the hydrogel structure to improve quality of the hydrogel (group 4). Then, the physicochemical, mechanical and biological properties of the hydrogels were evaluated. The results showed, molar ratio of polymers not only plays an important role in enhancing hydrophilicity, porosity, elastic modulus-like soft tissues, and cell proliferation, but also the presence of methyl cellulose lead to the improvement of the mentioned properties. So that, hydrogels of groups 1 and 4 provide an ideal environment for improving cellular activities due to hydrophilicity of more than 51%, elastic modulus-like cardiac tissues (68.1 kPa and 79.22 kPa, respectively), biocompatibility above 90%, with compared to other groups. It seems that the mentioned hydrogels (1 and 4 groups) can imitate soft tissue properties such as cardiac and be effective to regenerate and repair. In the other hand, these thermosensitive and inject ability hydrogels lead to a uniform mixing of cells and growth factors, as well as can apply to the cell therapy of soft tissue. Manuscript profile
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  7 - The effect of temperature of equal- chanel angular pressing process on mechanical properties and biocompatibility of titanium dental implant
  محمد خدائی Payam Eslamian mahmood meratian Mahdi Hadavi
  Biometals such as stainless steels, tantalum, titanium, cobalt and their alloys are widely used for medical implants for bone and dental healing. Researches indicates that metals such as cobalt, chromium, nickel, aluminum and vanadium, release ion in vivo, which make th More

  Biometals such as stainless steels, tantalum, titanium, cobalt and their alloys are widely used for medical implants for bone and dental healing. Researches indicates that metals such as cobalt, chromium, nickel, aluminum and vanadium, release ion in vivo, which make the human body sensitive to the allergy and so implant lessening. The biocompatibility and non-toxic ion release of titanium is suitable for human body implantation, but it is needed to improve its strength. Nano-structured pure titanium is a newly developed method to increase the strength of implants, and increase their efficiency. In this research some parameters of Equal Chanel Angular Pressing (ECAP) like number of passes and temperature were investigated. After ECAP processing on pure titanium, the mechanical, metallurgical and biological properties of the products were investigated using standard tests. Results indicated that using ECAP process and reducing the titanium grain size from 14 micron to 440 nanometer, its mechanical and biological properties improved. Results of biocompatibility measurement indicated that the processing temperature of 240 ◦C make a very good biocompatibility with Adipose-derived stem cells (ASCs). Also the biocompatibility of titanium increased by increasing the number of the ECAP passes. The processed titanium at 240 ◦C for 4 passes, could be introduced as the choice during the other candidates. Manuscript profile
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  8 - Improving the Biocompatibility Performance of Ti-6Al-4V Alloy with Bi Phasic Calcium Phosphate Gradient Coating By Plasma Spray Method
  fahimeh saji iman mobasherpour liela nikzad
  10.30495/apme.2021.1925953.2035
  Due to the problems of metal implants, it is observed that one of the main techniques in solving these problems is to improve the properties of implant coatings. One of the coatings that has been considered in the last decade is biphasic calcium phosphate gradient coati More

  Due to the problems of metal implants, it is observed that one of the main techniques in solving these problems is to improve the properties of implant coatings. One of the coatings that has been considered in the last decade is biphasic calcium phosphate gradient coating. Plasma spraying method was used to coating the implants and three coating layers including HAp, TCP 50%-HAp 50% and TCP were applied gradient on the titanium substrate, respectively. X-ray diffraction test was used to identify the phases. Corrosion of the applied layers was performed using body simulation solution and open circuit potential electrochemical tests were used to evaluate the corrosion of coating. Field emission scanning electron microscopy was used to observe the morphology and thickness of the layers before and after being placed in the body simulation solution. According to the results of open circuit corrosion potential test, the corrosion voltage is -0.07, -0.09 and -0.19 V for the sample with one layer of HAp coating, the sample without coating and the sample with three layers of coating HAp, TCP 50%-HAp 50% and TCP were obtained respectively. By placing the three-layer coating in SBF solution, tricalcium phosphate in the third and second layers is completely dissolved and with the presence of calcium and phosphorus ions in the form of saturated secondary hydroxyapatite is formed inside the coating. Manuscript profile
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  9 - Fabrication and Evaluation of Morphological, Structural and Biocompatibility Properties of Chitosan Nanofibrous Scaffolds Coated with ZIF-8 Metal-organic Framework for Application in Wound Dressing
  Mahdi Hasanzadeh
  In this study, chitosan-based nanofibrous scaffold was produced for application in wound dressing by electrospinning method. Then, the zinc-based metal-organic framework (ZIF-8) was in situ synthesized method on nanofibrous scaffold. The effect of growth time of ZIF-8 c More

  In this study, chitosan-based nanofibrous scaffold was produced for application in wound dressing by electrospinning method. Then, the zinc-based metal-organic framework (ZIF-8) was in situ synthesized method on nanofibrous scaffold. The effect of growth time of ZIF-8 crystals on chitosan nanofibrous scaffolds was studied in order to achieve a uniform and continuous coating. The morphology and structure of the produced scaffolds were evaluated using scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). In order to evaluate the potential of fabricated scaffolds in wound dressing, surface wettability, antibacterial activity, biocompatibility and cell viability were also investigated. The electron microscope images showed that after 30 minutes, ZIF-8 nanoparticles grew with a relatively uniform distribution with an average size of 80 nm on the chitosan scaffold. The results showed that the scaffolds were biocompatible after 24 hours of cell culture and also had antibacterial properties against Gram-negative and Gram-positive Escherichia coli and Staphylococcus aureus, respectively. Due to the appropriate structural and morphological properties as well as the appropriate biocompatibility and antibacterial performance of the nanofibrous scaffold coated with a metal-organic framework, it can be used as a suitable candidate in wound dressing applications. Manuscript profile