List of Articles میوکارد

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  1 - Cardio metabolic adaptation to exercise: a review article
  Nahid Mohammadi javid Mehran Ghahramani
  10.30495/pah.2022.698098
  Abstract  Aim:  The aim of this study was to investigate the Cardio metabolic adaptation to exercise. Methods: In this research, cardiac muscle metabolism, myocardial energy production, myocardial energy storage and myocardial energy use, cardiac metabolism More

  Abstract  Aim:  The aim of this study was to investigate the Cardio metabolic adaptation to exercise. Methods: In this research, cardiac muscle metabolism, myocardial energy production, myocardial energy storage and myocardial energy use, cardiac metabolism in ischemia and arrhythmia, the role of AMPK enzyme in cardiac energy metabolism and its different forms of AMPK during reperfusion, the role of AMPK during reperfusion, adaptation of cardiac metabolism  to chronic hypoxia, the role of mitochondrial calcium in myocardial metabolism and finally the effect of endurance training and cardiac metabolism were investigated. Results:    The finding showed that the myocardium has the ability produce energy from several substrates including: it contains fatty acids, glucose, lactate, pyruvate, ketone bodies and some amino acids. The use of substrates specifically depends on the concentration of these substances in cardiac muscle cells and blood. Conclusion:    It can be concluded that cardiac muscle metabolism is affected by exercise and endurance training has a positive effect on myocardial metabolism.   Manuscript profile
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  2 - کاربرد نانو پلیمرهای زیستی در درمان صدمات قلبی
  بهزاد یثربی محدثه سیفی زهرا سلیمان زاده عاطفه بدر
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  3 - The effect of intra-myocardial injection of secretion of bone marrow-derived mesenchymal stem cell on Myocardial infarction in male rabbits
  narges kakadezfuly maryam naseroleslami nahid aboutaleb
  Background and Aim: Despite the use of stem cells in the treatment of diseases, especially heart disease, there is a lot of ambiguity about the act of cells and their secretions. Therefore, the purpose of this study was to evaluate the effect of secretion of bone marrow More

  Background and Aim: Despite the use of stem cells in the treatment of diseases, especially heart disease, there is a lot of ambiguity about the act of cells and their secretions. Therefore, the purpose of this study was to evaluate the effect of secretion of bone marrow-derived mesenchymal stem cells on myocardial infarction in male rabbits. Materials and Methods: After isolating the stem cells from the bone marrow and preparing the conditioned medium, 30 Male rabbits were randomly divided into three groups(n=10). Myocardial Infarction was induction in two groups and in a group conditioned medium was injected into the hearts of rabbits. Then in the first, fourth and eighth weeks, the heart parameters (HF, EF) were measured by echocardiography and then TNF-α factor was measured in the serum. Heart tissue was removed and the level of angiogenesis and fibrosis were investigated. Results: In the treated group with conditioned medium, the heart parameters (HF, EF) and angiogenesis increased significantly and decrease the level of TNF-α factor and fibrosis was significant in comparison with the Myocardial Infarction group (P<0.05). Discussion: Since the cardiac tissue and its function improved in this research, it seems that the secretion of bone marrow-derived mesenchymal stem cells have therapeutic effects on myocardial infarction. Manuscript profile
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  4 - Echocardiographic and radiographic study of left sided dilated cardiomyopathy in small breed dogs
  Boshra Elyasi Mohammad Nasrollahzade Masouleh Hamid Taghipour Sajad Mami
  10.30495/jvcp.2023.1982423.1400
  Dilated cardiomyopathy (DCM) is one of the most common cardiac diseases in dogs. Prompt diagnosis of the disease is very important as it may lead to fatality in undetected and untreated cases. This study was carried out to investigate and identify the echocardiographic More

  Dilated cardiomyopathy (DCM) is one of the most common cardiac diseases in dogs. Prompt diagnosis of the disease is very important as it may lead to fatality in undetected and untreated cases. This study was carried out to investigate and identify the echocardiographic and radiographic indicators of dogs with DCM by sex, sterility status, breed, age and weight. For this purpose, using echocardiography and radiography, various parameters of the left ventricle and VHS (Vertebrae Heart Scale) of all dogs with DCM were measured. The results showed that the highest rate of prevalence was related to unsterilized male terrier dogs with the age of 6-9 years and body weight of 5-10 kg. The echocardiographic findings showed that there were significant differences in different ages (p=0.05) between the parameters of IVSs (Intraventricular Septum at end Systole) and LVDs (Left Ventricular Internal Diameter at end Systole) in male and female DCM dogs, EF (Ejection Fraction) and FS (Fractional Shortening) of different sterility status, LVD (Left Ventricular Internal Diameter) and RVD (Right Ventricular Internal Diameter) of different breeds, all parameters measured in different weights and EF, LVDd (Left Ventricular Internal Diameter at end Diastole) and LVDs. The average VHS of dogs with breed, age, sterility status and different weights with DCM were significantly different from each other (p=0.04, p=0.04 and p=0.01). But, the findings showed that gender had no effect on VHS change. It seems that detection of the canine population with DCM disease according to related diagnostic imaging findings can help in the early diagnosis of this disease. Moreover, the findings of this research can be considered as a valid reference in the examination of different dogs with DCM. Manuscript profile
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  5 - Studying MiR-133 influencing the process of apoptosis of Cardiomyocytes floating in blood serum of patients suffering from acute Myocardial Infarction
  shiva kasiolkheir changiz ahmadizadeh hoshang hosseinzadeh mogbeli
  Abstract Background and goals: Myocardial Infarction is known as one of the most common disabling and threatening heart diseases resulted from irrevocable and degenerative cellular death in a part of heart muscle. After the discovery of miRNA in 1990 and the discovery o More

  Abstract Background and goals: Myocardial Infarction is known as one of the most common disabling and threatening heart diseases resulted from irrevocable and degenerative cellular death in a part of heart muscle. After the discovery of miRNA in 1990 and the discovery of more than 2500 types of miRNA, gradually the importance of these mechanism regulators and molecular signals and gene routes were identified in the processes and the cellular mechanisms, specifically in cardiovascular system. The goal of this research is Studying MiR-133 influencing the process of apoptosis of Cardiomyocytes floating in blood serum of patients suffering from acute Myocardial Infarction Methods: To achieve our goals in this case-observation study type regarding miR-133, 70 patients in Shahid Madani Hospital in Tabriz in the year 2017 were investigated by Real time PCR and the data were compared with those of the healthy persons. The statistical analyses were carried out using SPSS (version19) and a t-test method. The amounts for P>0.05 were considered meaningful. Findings: The expression levels of miR-133 among patients suffering from MI have had a considerable increase compared with control group and it was meaningful statistically. (P=0.009). Also the results showed that miR-133expression among fat and normal people did not have a meaningful difference statistically (P=0.06). Conclusion: The present study showed that the expression of miR-133among individuals suffering from MI has been greater than healthy people and it can be utilized as an identification factor and also prognosis of the patients suffering from MI. Manuscript profile
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  6 - Investigation of the Level of Serum Troponin I and Comparing it with Serum CK-MB in Diagnosis of Myocardial Infarction
  جمال شمسی پریچهره یغمایی میرحسین سید محمدزاده سید علی حائری روحانی
  The Myocardial infarction (MI) is the fail in reaching blood flow and sufficient oxygen to part of the heart. Te outbreak of MI symptoms might be various and the electrocardiography is not diagnostic in about 50% of the cases that is a potential danger for wrong diagnos More

  The Myocardial infarction (MI) is the fail in reaching blood flow and sufficient oxygen to part of the heart. Te outbreak of MI symptoms might be various and the electrocardiography is not diagnostic in about 50% of the cases that is a potential danger for wrong diagnosis, therefore we need to test the cardiac biomarkers. In this survey the level of Troponin I serum in the diagnosis of the cardiac infarction with CK-MB serum, in 40 MI patients and 40 cardiac patients without MI of Seyyed Al Shohada Heart Hospital in Urmia has been evaluated and compared. the Troponin I through Immunoenzymometric method using AccuBind Kit and CK-MB through DGKC (German Society of Clinical Chemistry) method and IFCC (International Federation of Clinical Chemistry) using Pars Azmun Company kit through photometric method, measurement. and then Conducted  the results' statistical analysis using SPSS 21 software and an independent T-test The results achieved from the comparison between the cTnI and CK-MB of MI patients and patients without MI showed that there was a significant difference between the cTnI of patients without MI and MI patients and also the CK-MB of patients without MI and MI patients at the level of (P) and the cTnI and CK-MB of MI patients is more than patients without MI. therefore their use is necessary for on time diagnosis and treatment of Myocardial infarction. In this survey the cTnI and CK-MB was compared from the viewpoint of sensitivity and specification that regarding the results the cTnI sensitivity and specification with 100% and 97.5% respectively was more than the CK-MB sensitivity and specification with 91% and 75% respectively. Manuscript profile