Background and objectives: Anxiety is one of the current psychic disorders among humanistic communities. It is an oppressive feeling that associates an unknown and ambiguous danger. Due to the effect of cuminum cyminum L, this study aims to consider the effect of hydroa More
Background and objectives: Anxiety is one of the current psychic disorders among humanistic communities. It is an oppressive feeling that associates an unknown and ambiguous danger. Due to the effect of cuminum cyminum L, this study aims to consider the effect of hydroalcoholic extract of cuminum cyminum L. on anxiety among male Adult wistar rats. Material and Methods: After recognition of the cuminum cyminum L. plant through herbarium of Islamic Azad university of Qom, the hydroalcoholic extract was extracted by laboratory, and the extract powder was produced by using an oven. In this study on 32 male wistar rats (200 230 gr) in healthy groups(intact),the treatment group with DMSO or the solvent extract (0/3 cc), and groups received 50,100 mg/kg hydroalcoholic extract of cuminum cyminum L. (n=8). All injections were peritoneal, and half an hour after injection, with the use of high cross labyrinth, anxiety test was taken, and anxiety evaluation’s standard indicators (staying period and the number of entering to free arm) were considered and registered for 5 minutes. Data were analyzed by the Tukey’s unilateral variance analyze (p<0.001). Results: The received group solvent extract than intact group indicators showed no significant differences in anxiety. the hydroalcoholic extract of cuminum cyminum L.in 100 mg/kg, showed significant increasing in presence period and number commuting time on open arm, than the group who received DMSO (p<0.001). Conclusion: the hydroalcoholic extract of cuminum cyminum L. has anti-anxiety effects.
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Anxiety is a common disorder of unknown origin associated with an unpleasant feeling .According to the anxiolytic effects Trachyspermum Copticum traditional medicine , trachyspermum Copticum effect on anxiety male Wistar rats were investigated. trachyspermum. copticum s More
Anxiety is a common disorder of unknown origin associated with an unpleasant feeling .According to the anxiolytic effects Trachyspermum Copticum traditional medicine , trachyspermum Copticum effect on anxiety male Wistar rats were investigated. trachyspermum. copticum seed after detection by the University Herbarium, hydro-alcoholic extract was extracted by Soxhlet and the extract powder was prepared using smart legitimate. In this study, male Wistar rats (230 ± 20 g) were placed In groups intact, recipient of the DMSO (solvent extraction) (0.3 cc), received obtained in different doses of 50, 25, 15 mg/kg. All injections were performed intraperitoneally. Half an hour after injection, anxiety was measured using the elevated plus maze. Indicators of anxiety for 5 minutes, including time spent and number of entries into the open arm was recorded. Data were analyzed by ANOVA statistical tests and Tukey test (p <0.05) .The results showed that the group receiving the extract solvent (DMSO) compared to intact in time spent and number of entries into the open arm does not show a significant difference. The group receiving a dose 15 mg/kg compared to the group receiving DMSO in time spent and number of entries into the open arm showed a significant increase. C. copticum hydro-alcoholic extract anxiolytic effects in low doses.
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Anxiety is a common disorder of unknown origin is associated with an unpleasant feeling .According to the anxiolytic effects TC traditional medicine , trachyspermum Copticum effect on anxity male Wistar rats were investigated. trachyspermum copticum seed after detection More
Anxiety is a common disorder of unknown origin is associated with an unpleasant feeling .According to the anxiolytic effects TC traditional medicine , trachyspermum Copticum effect on anxity male Wistar rats were investigated. trachyspermum copticum seed after detection by the University Herbarium, hydro-alcoholic extract was extracted by Soxhlet and the extract powder was prepared using smart legitimate. In this study, male Wistar rats (230 ± 20 g) were placed In groups intact, recipient of the DMSO (solvent extraction) (0.3 cc), received extract in different doses of 50, 25, 15 mg/kg. All injections were performed intraperitoneally. Half an hour after injection,anxity was measured using the elevated plus maze.Indicators of anxity for 5 minutes,including time spent and number of entries into the open arm was recorded. Data were analyzed by ANOVA statistical tests and Tukey test (p <0.05) .The results showed that the group receiving the extract solvent (DMSO) compared to intact in time spent and number of entries into the open arm does not show a significant difference. The group receiving a dose 15 mg/kg compared to the group receiving DMSO in time spent and number of entries into the open arm showed a significant increase. C. copticum hydro-alcoholic extract anxiolytic effects in low doses. Keywords: hydroalcoholic extract, Trachyspermum copticum, Anxiety, elevated plus maze, Male rats.
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Anxiety is a common disorder of unknown origin is associated with an unpleasant feeling. According to the anxiolytic effects TC traditional medicine, Trachyspermum copticum effect on anxiety male Wistar rats was investigated. T. copticum seed after detection by the univ More
Anxiety is a common disorder of unknown origin is associated with an unpleasant feeling. According to the anxiolytic effects TC traditional medicine, Trachyspermum copticum effect on anxiety male Wistar rats was investigated. T. copticum seed after detection by the university herbarium, hydro-alcoholic extract was extracted by Soxhlet and the extract powder was prepared using smart legitimate. Male Wistar rats (230 ± 20 gr) were placed. In groups intact, recipient of the DMSO (solvent extraction) (0.3 ml), received extract in different doses of 50, 25, 15 mg/kg. All injections were performed intraperitoneally. Half an hour after injection, anxiety was measured using the elevated plus maze. Indicators of anxiety for 5 min, including time spent and number of entries into the open arm was recorded. Data were analyzed by ANOVA statistical tests and Tukey test. The group receiving the extract solvent (DMSO) compared to intact in time spent and number of entries into the open arm did not show a significant difference. The group receiving a dose of 15 mg/kg compared to the group receiving DMSO in time spent and number of entries into the open arm showed a significant increase. T. copticum hydroalcoholic extract has anxiolytic effects in low doses.
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