List of Articles فنل و فلاونویید

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  1 - The combined effect of cold stress and polyamine supplement on some phytochemical parameters of Stevia rebaudiana (Bertoni) Bertoni.
  Kamran Moradi Peynevandi Syed Mehdi Razvi Saber Zahri
  Stevia rebaudiana (Bertoni) Bertoniis a perennial herb belongs to Asteraceae family. The plant has been cultivated in all over of the world for its sweetener compounds such as: steviol glycosides. In this study to evaluate the effects of cold stress (4ºC) combined More

  Stevia rebaudiana (Bertoni) Bertoniis a perennial herb belongs to Asteraceae family. The plant has been cultivated in all over of the world for its sweetener compounds such as: steviol glycosides. In this study to evaluate the effects of cold stress (4ºC) combined with polyamine supplement on some phytochemical parameters an experiment was carried out in a randomized design with three replications. The phytochemical measurement were obtained by spectrophotometery methods consisted of  Folinciocalteu  method for tanins-phenols, aluminium chloride method for flavonoids,  Anthon reagent for soluble sugars and spectrophotometer for anthocyanins and steviol glycosides. The treatments were conducted in six groups contained of cold and cold-polyamine treatments in 0, 48 and 96-hours of cold courses. The measurements were performed on the plant leaves at vegetative stage at Mohaghegh Ardabili University in May 2017. The results showed that the cold stress tends to a significant increase in all of measured parameters at p≤0.05. This increase was higher in the cold-polyamine treated plants than cold only treated groups of the plant. The results indicated that total soluble sugar and steviol glycosides were increased 233 and 35 percent, respectively, than control at 96-h cold combined with polyamine treatment. At same treatment, total flavonoid, anthocyanin, total phenol and tannin contents were increased up to 40, 100, 20 and 66 percentage than control, as well as. At the same plant group, the plant antioxidant potential was also elevated 20 percentage than control ones. It can be concluded thatcombined treatment of Stevia rebaudiana with cold and polyamine supplement can induced the secondary metabolite biosynthesis in the plant and hence might be tend to a considerably increasing in the plant pharmaceutical potential. Manuscript profile
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  2 - Total phenol, flavonoid contents and antioxidant activity of Gundelia tournefortii L. in different phenological stage and habitats of North East of khozestan province
  Lila Khalasi Ahwazi gholm Alh Heshmati Parzhak Zofan Mousa Akbarlou
  Gundelia tournefortii L. is an endemic valuable forag - medicinal plants, belongs to Asteraceae family.  This study was evaluated to total phenol, flavonoide content and antioxidant activity of  Gundelia tournefortii  L. in different stages of growth from More

  Gundelia tournefortii L. is an endemic valuable forag - medicinal plants, belongs to Asteraceae family.  This study was evaluated to total phenol, flavonoide content and antioxidant activity of  Gundelia tournefortii  L. in different stages of growth from four habitats  in north east of Khozestan province (900 m). The aerial parts of plant were collected from 4 natural habitats (Dare-Khorson, Shahzade Ahmad1, Shahzade Ahmad2 and Dehdez) in three stages: vegetative, flowering and seed dispersal. Total phenol (TP) and total flavonoids (TF) of methanol extracts were measured by spectrophotometry and antioxidant activity by scavenging free radicals of DPPH and then were analyzed based on multivariate variance (MANOVA). Results were showed that in all habitats, plant parts and phenological stages of plant had significant effect on antioxidant activity, total phenol and flavonoid contents of plant in 99 percent (P<0.01). The maximum amount of TP (56.9), TF (7.03 ) and antioxidant activity (0.19 ) were reported in Dare-Khorson region. Also in all regions the plant extract in blooming had higher content of TP, TF and antioxidant activity. Manuscript profile
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  3 - Phytochemical and antioxidant activity of Elaeagnus angustifolia L. fruits in different regions of Shahrood
  esmaeil Babakhanzadeh Sajirani Seyyed Javad Mousavizadeh Khadegheh Mozafari
  Elaeagnus angustifolia L. is one of the most important medicinal fruits which had a lot of secondary metabolites such as phenols and flavonoid and has been used in traditional medicine. The presences of flavonoids, phenols and antioxidant properties have been reported i More

  Elaeagnus angustifolia L. is one of the most important medicinal fruits which had a lot of secondary metabolites such as phenols and flavonoid and has been used in traditional medicine. The presences of flavonoids, phenols and antioxidant properties have been reported in fruits of Elaeagnus angustifolia L. In this research the ripe fruits of plant were collected from different regions of Shahrood (1000-1400m). The methanol extracts were obtained by maceration, total phenol and flavonoids contents were measured by spectrophotometery and antioxidant activities were analyzed by DPPH method. The results were showed that in higher region (1400m) the fruit extract of plant had the greatest amount of total phenol, flavonoids and antioxidant activity. So we observed that there is the correlation between altitude ot the region with quality and quantities of medicinal metabolites and antioxidant properties. Manuscript profile
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  4 - Evaluation of total phenol and flavonoid content, antioxidant activity, anti-pain and anti-inflammatory of Ocimum basillicum var. purpurescens in comparison with opioid drug (morphine) in male rats
  Solmaz Fakhari Isa bilejani Arash Khaki Asghar Rajabzadeh Masoumeh Mazandarani
  This study was carried out to evaluate the total flavonoide, phenols, antioxidant, anti-pain and anti-inflammatory in different extracts of Ocimum ebasillicum var. purpurescens in comparison with opioid drug (morphine) in male rats. The male Wistar rats with 250± More

  This study was carried out to evaluate the total flavonoide, phenols, antioxidant, anti-pain and anti-inflammatory in different extracts of Ocimum ebasillicum var. purpurescens in comparison with opioid drug (morphine) in male rats. The male Wistar rats with 250±10 g weighing was used and randomly divided to five groups. Group I (treated by 0.1mg/kg acetic acid, II-IV (treated by 0.7, 0.9 and 1 mg/kgof plantextract) , V (treated by 0.1 mg/kg morphine) and evaluated by Writhing test. The total phenol and flavonoids content was evaluated by follin-ciocalteus reagent, Ammonium chloride, the antioxidant activity was measured by DPPH method  and  serum levels of PGE2 and SOD activity measured by ELISA Kits.  According to results, the ethanol extract of plant had more content of secondary metabolites with total phenol (288.3±51.5 mg EGA/g) content, flavonoide content (154.7±1.04mg EGU/g) and the highest ability of free radicals scavenging (79.4±4.1%). There was a significant correlation between phenol- flavonoid ingredients to antioxidant activity rate and free radicals scavenging of plant (P<0.05, r<0.9) extract. High dosages of plant extract could be decreased chronic pains, in addition, serum level of PGE2 has been showed a significantly decreasing in groups treated by Ocimum basilicum extract and morphine in compared to untreated group. The serum SOD of treated groups (plant extract) was observed near to morphine group (P<0.05). Anti-inflammatory and anti-pain effects of this plant statically were observed next to morphine. It is found that steadily consumption of herbal usage, as antioxidant and anti-inflammatory, could be medicated to inflammatory treatment and long-term pains instead of opioid drugs. Manuscript profile
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  5 - Comparing antioxidant activity along with total phenols and flavonoids contents of four different Marrubium spp. extracts in East Azarbaijan habitats
  Negar Nazeri Fatemeh Fathiazad Sanaz Hamedeyazdan
  Marrubium genus belongs to the family Lamiaceae which is one of the precious genara native to Iran. Phytochemical studies upon Marrubium spp. are so limited so we decided to study four species of genus Marrubium native to Iran. The aerial parts of four Marrubium spp. (M More

  Marrubium genus belongs to the family Lamiaceae which is one of the precious genara native to Iran. Phytochemical studies upon Marrubium spp. are so limited so we decided to study four species of genus Marrubium native to Iran. The aerial parts of four Marrubium spp. (M. crassidens, M. persicum, M. propinquum, and M. parviflorum) were collected during their flowering stages from Varzeghan and Marand provinces from Azarbaijan, Iran in 1395. Dried plant materials were solvent extracted separately with petroleum ether, chloroform and methanol via maceration method. Afterwards, the antioxidant activities of the extracts were evaluated through scavenging the free DPPH radicals. Besides, the total phenolic and flavonoid contents of the extracts were verified based on colorimetric relative techniques. The antioxidant evaluation established the lowest RC50 of 11.1μg/mL for the 40% Sep-Pak fraction of the M. crassidens methanol extract. Moreover, petroleum ether extracts revealed no antioxidant activity. The most total phenolics and flavonoids content of the extracts were for M. crassidens methanol extract with 512.6 mg gallic acid equivalent and 212.7 mg quercetin equivalent both in 100 g dried plant material. In the study, presence of phenollics and flavonoids in different levels alongside prominent antioxidant activities were detected for the four Marrubium spp. native to East Azerbaijan. Overall, M. crassidens possessed higher phenolic and flavonoid contents resulting in superior antioxidant activity compared to other three species. Manuscript profile
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  6 - Evaluation of phytochemical and antioxidant activity of three widely-used medicinal plant in natural habitats of Fars province
  Auob mazaraie leila fahmideh
  Growth and generation of plants in different ecosystems and natural habitats are influenced by various factors. The present study aimed to evaluate and compare the phytochemicals and antioxidants of three widely-used medicinal plant species including Zataria multifolia More

  Growth and generation of plants in different ecosystems and natural habitats are influenced by various factors. The present study aimed to evaluate and compare the phytochemicals and antioxidants of three widely-used medicinal plant species including Zataria multifolia Boiss, Matricaria chamomilla L. and Achilla millefolium L. which grown in five natural habitats (Fasa, Firoozabad, Kazeroun, Farashband and Dehram) located in Fars province, South of Iran . Phenolic and flavonoid contents of the extracts obtained by maceration (soaking) method were determined via Folin-Ciocaltiu and Aluminum chloride colorimetric, respectively. The antioxidant properties were also investigated through DPPH method. Based on the results, there is a positive correlation between plant secondary compounds and their antioxidant performance, and this relationship was quite significant for all three plant samples. Among the regions under the study, the highest phenolic and flavonoid compounds yields were detected in Farashband and Dehram regions, respectively. Among the results, the highest phenolic and flavonoid contents as well as antioxidant properties were identified in Achillea eriophora DC and Zataria multifolia Boiss species from Farashband and Dehram regions had the highest values. The differences observed in phenolic and flavonoid contents as well as antioxidant properties could be attributed to the effects of climatic conditions such as height above sea level on the investigated plants. Manuscript profile
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  7 - Effect of different solvents on the extraction of phytochemical compounds of Neem (Azadirachta indica A. Juss)
  Maryam Rahimi Javad Ali Soufiyan Zeynab Mohkami Ali Ali Ghorbani Ranjbari Fatemeh Bidarnamani
  10.30495/ejmp.2022.1953625.1681
  Neem (Azadirachta indica) that belongs to the Meliaceae family has many medicinal properties such as treatment of skin diseases, hypoglycemia, hypertension, cancer, and AIDS. In this study, to investigate the effect of different solvents on the quantity and quality of p More

  Neem (Azadirachta indica) that belongs to the Meliaceae family has many medicinal properties such as treatment of skin diseases, hypoglycemia, hypertension, cancer, and AIDS. In this study, to investigate the effect of different solvents on the quantity and quality of phytochemical properties of neem collected from Bahoklat area in Chabahar city, a factorial experiment was conducted in a completely randomized design in 2021. Ethanol, methanolic, n-hexane and acetone extracts of neem leaves and fruits were prepared by cold maceration method. Total phenol content, total flavonoid and antioxidant activity were measured by folin-cicalto reagent, aluminum chloride colorimetric and diphenylpicrylhydrazyl free radical scaving (DPPH) methods, respectively. The results showed that the effect of organ type, solvent type and their interaction on all measured traits was significant. Based on the results, the highest amount of total phenol (48.22 mg Gallic acid / g dry weight) was reported in acetone leaf extract, and the lowest amount (2.76 mg Gallic acid / g dry weight) was reported in hexane extract of fruit. In addition, the highest amount of total flavonoids was observed in acetoin fruit and leaf extracts (4.71 and 4.61 mg Quercetin / g dry weight, respectively) and the lowest amount (3.22 mg quercetin / g dry weight) was obtained in the hexane extract of fruit. The highest and the lowest antioxidant activity was detected in ethanolic leaf extract (94.77%) and acetone extract of fruit (12.02%), respectively. Therefore, neem leaf is suggested as a useful source of phenolic compounds and natural antioxidants. Manuscript profile