List of Articles ضخامت پوست

• Open Access Article
  • Abstract Page
  • Full-Text
  
  1 - Study of effect of olive oil on re-epithelialization of epithelial tissue in excision wound healing model in rats
  Abooei Mehrizi, M., Eidi A., Mortazavi, P. .
  Olive oil has been used for medical purposes. It has beneficial effects on cardiovascular and metabolic diseases, inflammatory and autoimmune diseases. The objective of this study was to find out the efficacy of topical administration of olive oil on dermal wound healin More

  Olive oil has been used for medical purposes. It has beneficial effects on cardiovascular and metabolic diseases, inflammatory and autoimmune diseases. The objective of this study was to find out the efficacy of topical administration of olive oil on dermal wound healing in rats. After creating full-thickness skin wounds on the back of 60 male Wistar rats, rats randomly divided into six groups, as control, sham, treatment and standard. Control group was intact. Sham group received eucerin as vehicle. Treated group received the olive oil at doses 2, 5 and 10%, dissolved in eucerin. Standard group were treated with phenytoin ointment 1%. Wound healing rats were calculated on days 3, 7, 11, 14, 18 and 21 post-wounding and the wound tissues were harvested at 3, 7, 14 and 21 days for histological studies. All of rats were sacrificed, and the skin around incision area was dissected and stained by Masson’s trichrome methods for tissue analysis. The results indicated a significant decrease in the diameter of wound in the treated and standard groups comparing to the control groups. A significant increase in the rate of re-epithelialization was observed at 14 days in the treated and standard groups compared to the control group. The results demonstrate that olive oil significantly accelerates cutaneous wound healing and its effect may be due to the increased re-epithelialization. It was concluded that it can be considered as a therapeutic agent for wound healing Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  2 - Histopathological evaluation of cyclosporin gel on full thickness skin transplantation (Allograft) in the rat
  Mofidi, A., Jahandideh, A., Hesaraki, S. .
  Nowadays, it is used to skin graft in spread. Cyclosporine is one of the most use and effective immunosuppressive drugs that it has side effect and toxicities on CNS, kidney and liver. In this research is tried to investigation of 0.5% cyclosporine gel effectiveness on More

  Nowadays, it is used to skin graft in spread. Cyclosporine is one of the most use and effective immunosuppressive drugs that it has side effect and toxicities on CNS, kidney and liver. In this research is tried to investigation of 0.5% cyclosporine gel effectiveness on allograft full thickness skin rejection in rat. In this experimental study is used to 45 wistar male adult rats as allograft recipient and 15 spiral hole (SD) male adult rats as allograft donor with age range between 14 to 15 week and mean weight: 200±10 gr. After general anesthesia, circles with 1.5 cm diameter containing epidermal and dermal layers had separated from SD donor rats with scalpel cutting and then these parts were grafted to shoulder center (midline) of wistar recipient rats. After transplantation, rats randomly divided to 3 groups with 15 rat (3groups of 5 each) (control, test and 0.5% cyclosporine gel) and then each of them was divided to 3 group with 5 rat (sampling groups in days: 3, 7 and 15). Any treatment is applied in control group. 10 mg/kg IP cyclosporine injected to test group, and in third group, 0.5% cyclosporine gel was applied in the graft place, daily. Then on days: 3, 7 and 15 after graft, it was done sampling from the graft location and applied histopathological studies on it. Then, Statistics data analyzed using kruskal wallis test with SPSS software. Investigations confirmed that cyclosporine gel using caused to significant reduce of vasculitis, folliculitis, dermatitis and dermal degeneration on 3 and 7 days after graft in comparison to control group (P<0.05) and single use of cyclosporine gel on day 15 after graft did not cause to skin graft rejection. By attention to this test challenges, cyclosporine gel has significant effects on Acceptance of skin grafts, but its single use did not cause to skin graft rejection. To more effect on skin graft acceptance can use to cyclosporine gel in combination with other immunosuppressive drugs. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  3 - اثر سطوح مختلف کنجاله آفتابگردان و نیاسین بر عملکرد، پارامترهای بیوشیمیایی، وضعیت آنتی‌اکسیدانی و کلسترول زرده مرغ‌های تخمگذار
  پ. باغبان-کنعانی ح. جانمحمدی ع.ر. استادرحیمی
  این آزمایش به منظور بررسی اثر سطوح مختلف کنجاله آفتابگردان و نیاسین بر عملکرد، پارامترهای بیوشیمیایی، وضعیت آنتی‌اکسیدانی و کلسترول زرده تخم ­مرغ مرغان تخمگذار انجام گردید. تعداد 960 قطعه مرغ تخمگذار لگهورن سویه تجاری های-لاین W-36 به طور تصادفی در قالب 12 جیره غذای More

  این آزمایش به منظور بررسی اثر سطوح مختلف کنجاله آفتابگردان و نیاسین بر عملکرد، پارامترهای بیوشیمیایی، وضعیت آنتی‌اکسیدانی و کلسترول زرده تخم ­مرغ مرغان تخمگذار انجام گردید. تعداد 960 قطعه مرغ تخمگذار لگهورن سویه تجاری های-لاین W-36 به طور تصادفی در قالب 12 جیره غذایی آزمایشی، 8 تکرار و در هر تکرار از 10 قطعه مرغ به عنوان واحد آزمایشی استفاده گردید. روش آزمایش به ­صورت فاکتوریل 3 × 4 در قالب طرح کاملاً تصادفی شامل 3 سطح کنجاله آفتابگردان (0، 10 و 15 درصد) و 4 سطح نیاسین (0، 175، 225 و 275 میلی گرم بر کیلوگرم) به مدت 10 هفته بود. خوراک مصرفی تحت تأثیر کنجاله آفتابگردان، نیاسین و اثر متقابل نیاسین و کنجاله آفتابگردان قرار نگرفت (05/0<P). تولید تخم ­مرغ، وزن تخم­ مرغ و توده تخم­ مرغ در مرغان تغذیه شده با سطح 15 درصد کنجاله آفتابگردان کاهش یافت (05/0>P). هر چند افزودن سطح 275 میلی­گرم بر کیلوگرم نیاسین موجب افزایش تولید تخم ­مرغ و توده تخم­ مرغ گردید (05/0>P). وزن تخم ­مرغ تحت تأثیر سطوح مختلف نیاسین قرار نگرفت (05/0>P). ضریب تبدیل خوراک تحت تأثیر سطوح مختلف کنجاله آفتابگردان قرار گرفت (05/0>P)، اما تحت تأثیر سطوح مختلف نیاسین و اثر متقابل نیاسین و کنجاله آفتابگردان قرار نگرفت (05/0<P). در حقیقت، سطح 15 درصد کنجاله آفتابگردان ضریب تبدیل خوراک را از 12/2 به 14/2 افزایش داد (05/0>P). بجز ضخامت پوسته، سایر پارامترهای کیفی تخم ­مرغ تحت تأثیر سطوح مختلف نیاسین قرار نگرفت (05/0<P). مکمل­سازی جیره غذایی با 15 درصد کنجاله آفتابگردان منجر به کاهش ضخامت پوسته از 29/0 به 28/0 گردید (05/0>P). سطح 275 میلی­گرم بر کیلوگرم نیاسین تأثیر معنی­داری بر استحکام پوسته تخم ­مرغ داشت (05/0>P). کلسترول زرده تخم ­مرغ به میزان قابل توجهی تحت تأثیر کنجاله آفتابگردان و نیاسین قرار گرفت (05/0>P). همچنین داده­های حاصل از این آزمایش نشان داد که غلظت آلانین آمینوترانسفراز، آسپارتات آمینوترانسفراز و تری ­گلیسیرید سرم تحت تأثیر کنجاله آفتابگردان، نیاسین و اثرات متقابل این دو قرار نگرفت (05/0<P). اما کلسترول سرم تحت تأثیر سطوح مختلف کنجاله آفتابگردان، نیاسین و اثرات متقابل این دو قرار گرفت (05/0>P). جیره­های آزمایشی خصوصیات آنتی­اکسیدانی سرم را تحت تأثیر قرار ندادند (05/0<P) Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  4 - Effect of rootstock type, fruit growth pattern and cell intensity of peel on pre-harvest fruit splitting in citrus
  Mehrnaz Alikhani Babak Babakhani Behrouz Golein Mahmoud Asadi Parvaneh Rahdari
  Pre-harvest fruit splitting each year causing a significant reduction in yield and the prevalence of fungal rot in citrus fruits. In this research, effect of rootstock and also, physical traits of fruits on the severity of pre-harvest fruit splitting were investigated. More

  Pre-harvest fruit splitting each year causing a significant reduction in yield and the prevalence of fungal rot in citrus fruits. In this research, effect of rootstock and also, physical traits of fruits on the severity of pre-harvest fruit splitting were investigated. For this purpose, a research was performed in 2016-17 based on RCBD statistical design with three blocks of three mandarin cultivars (Page, Kara and Cadoux) grafted on four rootstocks (Sour orange, Citrange, Citrumelo and Cleopatra mandarin) under dry farming condition in Tonekabon city (private orchard). Obtained results showed that, both two investigated factors had significant effects on this disorder. According to results, sour orange and citrumelo caused the highest and lowest fruit splitting respectively and two other rootstocks with no significant difference were at an intermediate level in this regard. The significant role of growth pattern, thickness and cell density of peel at the stylar end of fruits on pre-harvest fruit splitting, caused that Page and Cadoux have the highest and lowest percent of fruit splitting respectively. Results also showed that cell density on the peel of the split fruits was lower than healthy ones. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  5 - Histopathological effects of flowering shoot hydroethanol extracts of Hypericumperforatum on experimental full-thickness skin wound healing in rats
  , M AsghariehAhary M.R Farahpour,
  Wound healing has always been of great concern for the surgeon and therefore using different effective biologicalsubstances of either plant or animal origin for a faster and more effcient wound healing (repair) has been considered.The aim of this study was to investigat More

  Wound healing has always been of great concern for the surgeon and therefore using different effective biologicalsubstances of either plant or animal origin for a faster and more effcient wound healing (repair) has been considered.The aim of this study was to investigate the accelerating effects of Hypericumperforatumhydroethanolextracton open wound healing in rats. Study design: thirty-six adult male Wistar-albino rats (weight 200±10 g) wererandomly allocated to three groups (one control and two treatment groups). Two seven-mm, circular, fullthicknesses, skin wounds were created on the back of each rat (2 on the left and 2 on the right side). In the controlgroup, wounds were treated by an ointment with no extract. The treatment groups were treated by standardizedointment containing 1% and 2% Hypericumperforatum extract. For histopathological studies, the 3 groups weresubdivided into 4 subgroups with 4 rats in each. Samples were taken from the groups 1 to 4 on days 3, 7, 14, and21, respectively. After taking the sample, the rats were euthanized. The sequential wound biopsies were evaluatedhistopathologically for their heamorrage,neutrophils and lymphocyte, new vascularization and re epithelialization.According to the results of this study, the ointment with 2% extract was much better and slightly better than thecontrol and 1% extract ointments, respectively. Manuscript profile