The effect of Mycosorb on heamatological and serum biochemical parameters in broilers with experimental Aflatoxicosis

Subject Areas : Journal of Large Animal Clinical Science Research(JLACSR)

Received: 2021-08-01 Accepted : 2021-08-01 Published : 2011-09-23

Keywords: Broiler, Biochemical parameters, Aflatoxin, Mycosorb, Hematological,

Abstract :

In this study the effect of AflatoxinB (AF) and potential of organic absorbent (Mycosorb) performed on broiler chicken. A total 105 broiler chicks were divided into 5 equal treatment groups in a completely random design. The adsorbents mycosorb was added into the basal diets at 3 and 1 gr/Kg which contaminated with 0 and 1 ppm aflatoxin/ kg-1 from 2 to 42 days of experimental treatments: 1.Control, 2.AF(1ppm), 3.AF(0.05ppm) 4.Mycosorb (1gr/kg) + 1ppm (AF), 5. Mycosorb (1gr/kg) + 0.05ppm (AF). The results indicated that red blood cell, haematocrit and lymphocyte counts of chicks were significantly reduced in AF groups compared with the control group, while the heterophil counts increased significantly. Among serum biochemical parameters, the Aspartat trasaminas (AST), Gamma glutamil transferase(GGT), Lactate dehydrogenase (LDH) activity and billirubin values increased in AF groups (P<0.05). The addition of Mycosorb to the AF containing diet (groups4&5) significantly improved the biochemical and hematological parameters. The mycosorb had a significant effect on broiler final weight(P<0.05). These results  of this study clearly indicated that addition of adsorbent (Mycosorb) to the AF containing diet can reduce the toxic effects of AF.

References:

1-     صفامهر، ع. رو شیوازاد، م (1385): مطالعه اثرات کلینوپتیلولیت بر عملکرد و پارامترهای هماتولوژی و بیوشیمیایی سرم جوجه­های گوشتی مبتلا به آفلاتوکسیکوزیس مجله علوم کشاورزی و منابع طبیعی. جلد سیزدهم، شماره یکم، ویژه نامه علوم دامی.

2-     طلاکش، ف (1373): مایکوتوکسین ها و اثرات آن بر سیستم ایمنی. پایان نامه دکترای دامپزشکی ، شماره 2202، دانشگاه تهران

3-     کرمانشاهی، ح. اکبری ، م. ر. افضلی ، ن (1386): اثرات افزودن سطوح پایین آفلاتوکسین B₁ در جیره بر عملکرد و میزان فعالیت آنزیم­های خون در جوجه­های گوشتی مجله علوم کشاورزی و منابع طبیعی/ سال یازدهم/ شماره اول (ب)/ بهار 1386، صفحات 443-449.

4-     لطف الهیان، ه. شریعمتداری، ف . شیوازاد، م. میرهادی، س. ا (1383): بررسی اثرات استفاده از دو نوع زئولیت طبیعی در جیره های غذایی بر عوامل بیوشیمیایی خون، وزن نسبی اندام‌های داخلی و عملکرد جوجه­های گوشتی. پژوهش و سازندگی، شماره 64، صفحات 18 تا 34.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

5-      Baily, R. H., kubena, L. F., Harvey, R. B. Buckiey. S. A, and Rotting haus, G. E., (1991): Efficacy of various inorganic sorbent to reduce the toxicity of aflatoxin and T-2 toxin in broiler chickens, Poultry Science. 77: 1630-1632.

6-      Basmaclloglu H., H. Oguz. M. Ergul, R..Y.O .Birdane., (2005): Effected of dietary esterifies glucomannan of performance, serum biochemistry and haematology in broilers exposed to aflatoxin. Czech. Animal Science , 50, 2005(1): 31-39.

7-      Brugere, P., Brugere, H., Basset, I., Sayad, N. Vasst, J., Michaux, J., M, (1987): Bonhomie clinquant patalogie aviaire. In teret. In teret et limites des dosages enzymutiques chez lapoule. Recuel Medicine Veterinary, 163 , 1091-1099.

8-      Campbell, M.L. May, L.D. Huff, W.E., and Doerr, J. A., (1987): Evaluation of immunity of young broiler chivkensduring simultan eous oflatoxicosis and ochra toxicosis Poultry Science. 62: 2138-2144

9-      Harvey, R.B., Kabena, L.F, Elissalbe, M.H, and Phillips, T. D, (1993): Efficacy of zeolitic ore compounds on the toxicity of aflatoxin to growing broiler chickens. Avian disease. 37:67-73.

10-  Jassar, B.S., singh, B., (1993): Bioch emical change in experimental aflatoxicosis in broiler chickens. Indian journal of Animal science. 63:847-848.

11-  Kececi, T., oguz,H., hurtoglu, V., and Demet, O., (1998): Effects of polyvinyl poly pyrolidone, synthetic zeolite and bentonite on serum biochemical and haematological characters of broiler during aflatoxicosis.British Poultry science. 39:452-458.

 

 

12-  kubena, L. F., R. B., Harvey, R. H. Baily, S. A., Buckely, G. E., Rotting (1998): Effects of Hydrated sodium calcium Alumunosilicate (T-Bin TM) on my cotoxicosis in Young Broiler chickens.Poult.sci.77:1502-1509,

13-  leeson, S., Diaz,. G., summers, j. d., (1995): Aflatoxin. In:ortatatli, M., oGuz, H., Hatipoylu, F., Karman, M., (2005): Evaluation of pathology change in broilers during chronic Aflatoxin (50 and 100 ppb) and clinoptilolite exposure. Research in veterinary science 78, 61-68.

14-  Oguz, H., Hadimli, H. H., V., Erganism O., (2003): Envaluation of humoral immunity of broiler during chronic aflatoxin (50 and 100 ppb) and clinoptiholite exposure. Revue de Medicine veterinaire 154-483-486.

15-  Miazzo, R. peralta, M. F. magnolit, C.salvano , M.Ferrero,S. chiacchieral, S.M. carvalho, E.C. Q. Rosa, C, A. Rand Dalcero, A., (2005): Efficacy of sodium Bentonite as a Detoxifier of Broiler Feed contaminated with Aflatoxin and Fumonisin. Poultry science Association, Inc. 84:1-8.

16-  Oguz, H., Hadimli, H. H., V., Erganism O., (2003): Envaluation of humoral immunity of broiler during chronic aflatoxin (50 and 100 ppb) and clinoptiholite exposure. Revue de Medicine veterinaire 154-483-486.

17-  Phillips, T. D, Abo- Norge, M., Edrington, T. S., kubena, L. E., Harvey. R. B., (1995): Influence of a hydrated calcium aluminosilicate and virginiamycin on aflatoxicosis in broiler chickens- Poultry science. 74:626-632.

18-  Phillips,T.D.,B.A.Clement,L.F. kubena, and R.B., (1990): hervey, Detection and detoxification of aflatoxins: Prevention of aflatoxicosis and aflatoxin residue with hydrated sodium calcium   aluminosilicate veterinary Toxical. 32: 15-19.

19-  Phillips,T.D., kubena, L.F., hervey, R.B., Taylor, O.S., and Heidel bough, N. D., (1988): Hydrated sodium calcium aluminosilicate. A high affinity sorbent for aflatoxin. Poultry science.67:243-247.

20-  Quist,C.f.,D.I.Bounous,J.v.kilbum,V.F.Nattles, R. D., Waytt. (2000): the affect of dietary aflatoxin on wild turkey poults,j. wildlife Disease. 36:436-444.

21-  Rujo. M. V. L. Nand Devegowda, G., (2000): Influence of sterified glucomannan on performance and organ morphology, serum biochemistry and hematology in broilers exposed to individual and combined mycotoxicosis (aflatoxin, ochratoxin and T-2 toxin) British Poultry science, 41:640-650.

22-  Saif, Y. M., (2004): Diseases of Poultry. 11ed., Iowa state press, USA.pp:1109-1119.

23-  Shotwell,O.L.,Hesseltine, C.V.,subble field,R.D., and Sorenson, W.G., (1966): Production of aflatoxin on rice. Applied Microbiology. 14:425-428.

24-  Spss,Institute. (1982): Spss.Users Guide. Statistics. Spss institute Inc.,cary.NC.

25-  Tung, H. T., Waytt, R, D., Thaxton, P., Hamilton, P. B., (1975): Concentration of serum protein during aflatoxicosis. Toxically applied pharmacology, 34: 320-326.

26-  Wilson, T. J., Romer, T. R., (1991):Use of mycosep multifunction clean up colum for liquid chromatographic determination of aflatoxins in agricultural production.j. Animal. Biochemistry. 74: 951 -959.