AbstractAdhesion molecules are mediators of atherosclerotic inflammatory processes. Blood levels of these substances have direct association with cardiovascular disease risk and elevate in heart patients. The aim of this study was to examine the effect of two continuous (cooper test) and interval (RAST test) exercises on levels of ICAM1, VCAM1, E-selectin, P-selectin, and L-selectin. 17 obese and healthy young females were randomly assigned into two groups of Cooper and RAST tests. Blood sampling was done before and after the tests. In statistical analysis, paired T-test was used for interring group comparison and independent T-test was used for between groups comparison. Analysis of data showed that except L-selectin, changes of all dependent variables after cooper and RAST tests were not significant (P>0/05) and only L-selectin levels after cooper test decreased significantly (P≤0/05). Also changes of all of variables between two groups were not significant (P>0/05). overall, one session interval and continuous exercise did not induce elevation of atherogenic adhesion molecules in obese young females that shows protective mechanisms in vascular endothelium in these persons possibly prevents injurious inflammatory response to exercise, thus obese young females can do exercise for weight reduction without anxiety for inflammatory complications induced by exercise trainings.
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