Effects of Lavendula officinalis Aqueous Extract on Uterus Balb/C Adult Female Mouse.

Subject Areas :

ّFatemeh Soheili ¹ , Parvhn torabzadeh ² , Mina Ramazani ³

1 - کارشناسی ارشد، گروه زیست شناسی(تکوین جانوری)، دانشگاه آزاد اسلامی واحد کرج، البرز. ایران.
2 - استادیار گروه زیست شناسی(تکوین جانوری)، دانشگاه آزاد اسلامی واحد کرج، البرز. ایران
3 - دانشیار، گروه زیست شناسی(تکوین جانوری)، دانشگاه آزاد اسلامی واحد تهران مرکز ، تهران. ایران.

Received: 2017-06-18 Accepted : 2018-08-04 Published : 2017-07-23

Keywords: Uterus, Mouse, Key word: Lavendula officinalis, Uterine Glands,

Abstract :

Inroduction & ObjectiveIn addition to the sedative properties of Lavendula officinalis aqueous extract, it is effective on diabetes and depression and has antimicrobial properties. However, its effect on reproductive system has not been reviewed yet. Therefore, in this study the effect of Lavendula officinalis aqueous extract on Balb/C mouse uterus was investigated.Materials and Methods:In this study 65 Balb/C adult female mice. After injection of aqueous extract and observation lack of lethal symptoms, experiments was continued with selected doses: 6 (group1:15mice),12 (group2:15mice),18 (group3:15mice) g/kg.bw. Interperitoneally injections were done for 12 days on 65 mice. Results were compared with the control group (non-injection: 10 mice ) and sham (injection of normal saline:10 mice. Data was checked with SPSS 20 software ANOVA and Duncan post test ,subject to PResultsExperiments showed a significant decrease in uterine glands, diameter of uterus and thickness of endometrium, myometrium and perimetrium PConclusion: According to these observations, it can be concluded that Lavendula officinalis aqueous extract has detrimental effect on female uterus and may be use as a contraceptive pill in the future.