List of Articles
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Open Access Article
1 - A review of the role of perilipin in fatty liver with an exercise approach
Nafiseh Sadeghi Saleh RahmatiThe benefits of physical activity in individuals with fatty liver disease are widely acknowledged. Fatty liver disease occurs when an excessive amount of fat builds up in liver cells, resulting in inflammation and potential long-term liver damage. Perilipin, a protein p MoreThe benefits of physical activity in individuals with fatty liver disease are widely acknowledged. Fatty liver disease occurs when an excessive amount of fat builds up in liver cells, resulting in inflammation and potential long-term liver damage. Perilipin, a protein present in fat cells, plays a crucial role in regulating lipid metabolism, including the storage and breakdown of triglycerides. It has been scientifically proven that regular physical exercise has a positive impact on the connection between perilipin and fatty liver, creating a healthier environment for the liver. Physical activity enhances the expression and activity of perilipin, aiding in the release of stored triglycerides from liver cells. This allows for their metabolism and utilization as fuel during physical activity. Furthermore, physical activity stimulates lipolysis, the process of breaking down stored fat into free fatty acids, which can then be utilized for energy production. By increasing the activity of perilipin, this process is facilitated, preventing excessive accumulation of triglycerides in liver cells. Regular physical activity also increases energy expenditure and assists with weight management, as overweight and obesity are significant risk factors for the development and progression of fatty liver disease. The present study aims to investigate the relationships between perilipin, fatty liver, and the positive effects of physical activity on these interactions. Manuscript profile -
Open Access Article
2 - Compare the effects of two intense interval training (HIIT) protocol on some Immunological indices in young overweight girls
azizeh ahmadi rasoul dokhtabdiyanthis study purpose is to determining the effect of two types high intensity exercise (HIIT) on some Immunological indices in young overweight girls. 24 girls with age 25/75±1/18 y, height: 161/29± 4/23cm, weight 74/51±6/27 kg، fat 30/70± 2/23 Morethis study purpose is to determining the effect of two types high intensity exercise (HIIT) on some Immunological indices in young overweight girls. 24 girls with age 25/75±1/18 y, height: 161/29± 4/23cm, weight 74/51±6/27 kg، fat 30/70± 2/23%, BMI 28/66±1/89 kg/m2 voluntarily participated and randomly divided into three experimental HIIT1 group (n=8), HIIT2 group (n=8) and control group (n=8). Group HIIT1 in each session running four sets 30s with 19 to 20 rate of perceived exertion (RPE) Borg scale and two minutes of rest between sets. HIIT2 group running four sets of 60 s with the same intensity and four minutes rest between sets, training protocol performed three times a week and performed four weeks. 48 hours before and 48 hours after exercise, blood samples were taken. For analyzing data, use Mixed between-within Subjects analysis of variance in level of (P<0.05). mean percent of LYM, NEUT and NEUT levels did not change significantly (P>0.05). The mean of lymphocytes showed significant increase only in Group HIIT2 (P=0.005), difference between groups was not significant (P>0.05). leukocytes in the Both experimental groups was significant increase (P<0.05). The mean of immunoglobulin A in both experimental groups showed a significant increase (p<0.05). In the mean of immunoglobulin G, significant changes were observed only in HIIT1 group (p<0.05). immunoglobulin M did not change significantly in any of the groups (p>0.05). it seems that Short-term HIIT increase leukocyte counts and immunoglobulin A and G to a greater extent than medium-term HIIT. Manuscript profile