Biometals such as stainless steels, tantalum, titanium, cobalt and their alloys are widely used for medical implants for bone and dental healing. Researches indicates that metals such as cobalt, chromium, nickel, aluminum and vanadium, release ion in vivo, which make th
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Biometals such as stainless steels, tantalum, titanium, cobalt and their alloys are widely used for medical implants for bone and dental healing. Researches indicates that metals such as cobalt, chromium, nickel, aluminum and vanadium, release ion in vivo, which make the human body sensitive to the allergy and so implant lessening. The biocompatibility and non-toxic ion release of titanium is suitable for human body implantation, but it is needed to improve its strength. Nano-structured pure titanium is a newly developed method to increase the strength of implants, and increase their efficiency. In this research some parameters of Equal Chanel Angular Pressing (ECAP) like number of passes and temperature were investigated. After ECAP processing on pure titanium, the mechanical, metallurgical and biological properties of the products were investigated using standard tests. Results indicated that using ECAP process and reducing the titanium grain size from 14 micron to 440 nanometer, its mechanical and biological properties improved. Results of biocompatibility measurement indicated that the processing temperature of 240 ◦C make a very good biocompatibility with Adipose-derived stem cells (ASCs). Also the biocompatibility of titanium increased by increasing the number of the ECAP passes. The processed titanium at 240 ◦C for 4 passes, could be introduced as the choice during the other candidates.
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