Overview of PRP Applications in Veterinary Medicine
Subject Areas : Smal Animal MedicineMahan Yaghmaee 1 * , Amir hossein FouroghiFar 2
1 - Doctor of Veterinary Medicine Student, Faculty of Veterinary Medicine, Islamic Azad University, Shushtar Branch, Shushtar, Iran
2 - Doctor of Veterinary Medicine Student, Faculty of Veterinary Medicine, Islamic Azad University, Shushtar Branch, Shushtar, Iran
Keywords: Platelet-rich plasma, PRP, accelerated wound healing, corneal ulcer,
Abstract :
Platelet-Rich Plasma can accelerate the healing process by providing higher concentrations of platelet-derived growth factors.it has been used in various diseases. In a study on dogs with aural hematomas,17dogs were treated with L-PRP. Early recurrence was observed in 5 dogs, of which 3achieved complete recovery after a second treatment. In 10 dogs, after 7 days, the hematoma had reduced to less than 50% of its initial size or had completely disappeared .the treatment of corneal ulcers in 28 animals (16 cats, 12 dogs),50% of the dogs required 2 injections, while cats required 3 injections. Examination of biomarkers and matrix-degrading enzymes (MMP-2,MMP-9) indicated that PRP is an efficient method for promoting corneal ulcer healing. In a study on dry eye treatment in 20 dogs, the animals were divided into two groups: standard treatment and PRP treatment. The Schirmer Tear Test (STT) showed better results in the PRP group. In the treatment of distal limb wounds in horses, PRP gel resulted in faster healing in 62.5% of cases compared to the control group. PRP has been shown to increase the proliferation of tendon cells and enhance collagen and matrix synthesis, resulting in clinical improvement. When used alongside rehabilitation, PRP leads to faster recovery compared to rehabilitation alone. Combining PRP with autologous cancellous bone grafts in pigs resulted in enhanced bone regeneration. In the treatment of osteoarthritis, 5 dogs were treated with intra-articular allogeneic PRP gel.
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