Evaluation of cardiac troponin I alterationsin dairy cattle with septicmetritis

Subject Areas : Veterinary Clinical Pathology

majid  fartashvand ¹ (دانشگاه آزاد اسلامی، واحد تبریز، دانشکده دامپزشکی، استادیار گروه علوم درمانگاهی، تبریز، ایران.)
ali  derangian ² (دانشگاه آزاد اسلامی، واحد تبریز، دانشجوی دکترای دامپزشکی، تبریز، ایران.)
amirali  kaveh ³ (دانشگاه آزاد اسلامی، واحد تبریز، دانشکده دامپزشکی، استادیار گروه علوم درمانگاهی، تبریز، ایران.)

Received: 2013-12-03 Accepted : 2014-03-03 Published : 2013-11-22

Keywords: Post-parturient metritis, Septic metritis, Cardiac troponin I,

Abstract :

Metritis is an important disease in dairy cattle which causes economical loses including decrease in milk yield, increase calving interval, treatment costs and death of ill cases. Septic metritis usually occurs within 2-10 days after parturition, and characterized clinically with sever toxemia associated with purulent odorous uterine discharge with or without retained placenta. In this study, serum levels of cTnI were measured in 50 female Holstein cattle with septicmetritis and compared with normal cows. cTnI of serum in disease and control groups were 0.017 ± 0.008 and 0.005 ± 0.000 ng/dl, respectively. Heart rate, respiratory rate and rectal temperature in disease cases were significantly higher than normal cattle. There was significant correlation with cTnI and heart rate and rectal temperature. Endotoxemia is one of possible reasons of elevation of serum cTnI. Cytokines and endotoxins originated from gram negative bacteria that cause myocardium depression and ventricular dilatation. Furthermore impairment of left ventricle function is a significant effect of septic shock.  

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