The Impact of Resveratrol Supplementation on Oxidative, Inflammatory, and Cellular Damage Markers Following of High-Intensity Resistance Exercise in Non-Athletic Women
somayeh fatahi
1
(
Department of Physical Education and Sports Sciences, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
)
Akram Jafari
2
(
Assistant professor
)
Keywords: inflammation, resistance exercise, oxidative stress, resveratrol,
Abstract :
Background and aim: the aim of this study was to investigate the effect of resveratrol supplementation on certain oxidative, inflammatory, and cellular damage markers resulting from high-intensity resistance exercise in non-athletic women. Method: 24 healthy non-athletic women (body mass index 20-25 kg/m2, age 20-30 years) were randomly divided into two groups: placebo and resveratrol supplement (12 people in each group). The subjects of two groups took a supplement or a placebo for one week (supplement group 400 mg resveratrol daily and placebo group the same amount daily in the form of essential oil capsules) and then participated in a resistance activity session with 85% of a maximum repetition. In 3 stages (before Yari supplementation, before resistance training and immediately after resistance training) blood was taken and the levels of malondialdehyde, total antioxidant capacity, creatine kinase, c-reactive protein and uric acid were analyzed. Results: The results of the present study showed that seven days of resveratrol consumption in the supplement group led to an increase in total antioxidant capacity and a decrease in malondialdehyde levels compared to pre-supplementation (p ≤ 0.01). Additionally, resveratrol supplementation was able to prevent a significant increase in creatine kinase and a significant decrease in total antioxidant capacity after the resistance exercise (p < 0.05). Conclusion: The findings of the present research showed that resveratrol supplementation has protective effects against oxidative damage caused by intense resistance exercise in young women by reducing malondialdehyde and creatine kinase and increasing total antioxidant capacity. These beneficial effects are probably attributed
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