The effect of human gonadotropin and cinnamon hydroalcoholic extract on testes and seminal vesicles in adult male rats

Subject Areas : Developmental biology of plants and animals , development and differentiation in microorganisms

elnaz shikhzade mamoii ¹ , akbar karimi ² , Ali Asghar Pileh Varian ³

1 - university paiamenor esfehan
2 - Department of Biology, Payame Noor University, Tehran, Iran
3 - , Department of Biology, Payame Noor University, Tehran, Iran

Received: 2020-12-25 Accepted : 2021-07-15 Published : 2021-05-22

Keywords: Cinnamon, Testis, HCG, Seminal Vesicles, Wistar Rats,

Abstract :

Background and Aim: Since HCG stimulates the production of testosterone and increases androgen production, it is used in the treatment of infertility and in some cases, inflammatory conditions reduce its effect. In this study, due to the known anti-inflammatory effect of cinnamon, it was used as a supplement to influence the effect of HCG on sexual activity of Adult male rats.Materials and Methods: In this experimental study, 24 Adult male Wistar rats were randomly divided into 4 groups of 6 including control group (daily subcutaneous saline), one HCG treatment group (50 IU / ml daily). Subcutaneous), treatment group with two hydroalcoholic extracts of cinnamon (30 mg / kg daily intraperitoneally) and treatment group with three HCG and hydroalcoholic extract of cinnamon (50 IU / ml daily subcutaneous injection and 30 mg / kg intravenous injection daily). Peritoneal) were divided. The rats were treated for 7 days, anesthetized after 14 days and after hematoxylin-eosin staining testes and seminal vesicles were examined by light microscopy. Data were analyzed using one-way ANOVA.Results: The results of the present study showed that the mean testicular and seminal vesicle weight, seminal vesicle diameter and seminal vesicle thickness and reproductive membrane thickness were significantly higher in the HCG and cinnamon receiving group (P <0.001). ).Discussion & Conclusion: Based on the results of this study, the combination of hydroalcoholic extract of cinnamon and HCG could lead to better development and testicular and seminal vesicle function in Adult male rats