Developmental study of chemical composition of Centella asiatica (L) Urban as a medicinal plant

Subject Areas : Developmental biology of plants and animals , development and differentiation in microorganisms

علی  مازوجی ¹ (عضوهییت علمی دانشگاه آزاد اسلامی واحدرودهن)
فهیمه  سلیم پور ² (عضوهییت علمی گروه ریست شناسی دانشگاه آزاد اسلامی- تهران شمال)
لیلا  شفیعی دستجردی ³ (عضو هییت علمی دانشگاه آزاد اسلامی واحدرودهن)

Received: 2016-05-07 Accepted : 2016-08-15 Published : 2016-09-21

Keywords: Guilan, Medicinal plant, Centella asiatica, Development Essential oils,

Abstract :

Centella asiatica from Apiaceae family has 40 species in all over the world. It has Creeping herb, rooting at the nodes. Stems shallowly grooved, sometimes purplish. Leaves solitary or in groups of 2-5, kidney-shaped to almost circular, distinctly and broadly cordate at the base, up to 7 cm wide, hairless or with hairs on the petiole; margin crenate. Flowers in 2-8-flowered umbels, greenish-white to dark crimson. Fruit c. 3.5 × 3 mm, laterally flattened, round or ellipsoid, ribbed, brown when ripe.This species has medicinal properties for example, wound healing, Antioxidant, memory enhancement, Anti diabetic and so on. C. asiatica is distributed in Guilan province and plant materials are collected from three different stages of growth and development including beginning of growth, flowering and fruiting phase, and end of growth phase. The results are shown that essential oil yield was 0/16% (V/M) and 54 volatile compounds comprising 92.78% of total oil constituents were identified from C. asiatica. Sesquiterpenoids were the major class of volatile chemical (45/33%), with Germaerene-D as the predominant compound. (45.43%).

References:

[1] Bandara M. S., Lee F. L. and Thomas J. E. 2011. Gotu Kola (Centella asiatica L.) : An Under Utilized Herb. The American Journal of plant science and Biotechnology. 5 (2): 20-31

[2] Bylka W., Awizen P., Studzinska- Sroka E. and Brcezinska M. 2013. Centellaasiatica in cosetolegy. Postep Derm Alergol. 9: 46-49.

[3] Derkota A. and Jha P. K. 2009. Variation in gowth of centellaa siatica along Different soil
composition. Botany Research International. 2 (1): 55-60.

[4] Chong N. J. and Aziz Z. 2011. A systematic review on the chemical constituents of centella asiatica. Research Journal of pharmaceutical, Bilogical and Chemical Sciences. 2 (3) 445459.

[5] Francis S. C. and Thomas M. T. 2016. Essential oil profiling of centella asiatica (L.) Urban a medicinaly important herb. Sowth Indian Journal of Oil Biological Science. 2(1): 169173.

[6] Johan R., Hossain S., Seraj S., Nasrin D., Khatun Z., Roni P., Tabibul M. D., Ahmed I.andRahmetullah M. 2012. Centella asiatica (L.) Urban: Ethnomedicinal Uses and their scientific validations. American- Eurasian Journal of Sustainalle Agriculture. 6(4): 267- 270.

[7] Jelani S., Jobeen F., Prabhakar M. and Leelavothi P. 1993. Hparmacognostic studies on centella asiotica (L.) Urban. Ancient science of Life. 7(3,4): 439-450.

[8] Rattanakom S. and Yasurin P. 2014. Review: Antibacterial, Anti oxidant and chemical profile of centella asiatica. Bromedical & Pharmacology Journal. 7(2): 445- 451.

[9] Secvoratnam V., Banumathis P., Premlathon M. R., Sundaram S. P. and Arumagam T. 2012. Functronal Properties of centalla asiatia (L.): A Review. International Journal of Pharmacy and Pharmaccutical Sciences. 4(5): 8-14.

[10] Wong K. C. and Tan G. L. 2011. Essential oil of Centella asiatica (L.) Urb. Journal of essential oil Research. 6(3): 307-309.

[11] Zahara K., Bibi Y. and Tabassum S. 2014. Clinical and the rapeutic benefits of centellaasiatica. Pure and Applied Biology. 3(4): 152- 159.

[12] Zheng C. J. and Qin L., P. 2007. Chemical component of centella asiatica and their bioactivities. Journal of chineese integrative medicine. 5(3): 348-351.