Introduction & Objective: The purpose of this study was to investigate the effectiveness of Mindfulness Intervention on increasing the self-efficacy of neurological overeatingin Tehran. Method: This research is a semi-experimental design with pre-test and post-test design with control group. The statistical population of this study was outpatient outpatients with neurological overload referred to two nutrition clinics in Tehran during 1397. The final sample size of this study was 30 neurological overeatingsubjects who were selected by purposeful sampling and randomly assigned to two experimental groups (15 subjects) and control (n = 15). The Mindfulness Therapy Package was implemented in the form of 8 weekly 90-minute sessions on the development group. The research tool was the general self-efficacy scale of Sherer et al. (1982). Data were analyzed using covariance analysis. Findings: The results showed no significant difference between the experimental and control groups. And mindfulness therapy did not affect the self-efficacy of patients with neurological overeating. Discussion and conclusion: It is suggested that psychologists and counselors use the results in causative and behavioral and psychological problems of patients with neurological overeating. Manuscript profile