N-Methyl-Nʹ-propyltrimethoxysillylimidazolium chloride was prepared as ionic liquid (IL) containing silylating agent and then used for modification of the internal surface of SBA-15 to gain a heterogeneous ionic liquid catalyst. Subsequently, the obtained SBA-IL was characterized using various techniques, including SEM and TEM images, FT-IR, X-ray diffraction, TGA/DTA and BET analyses. It was found that the uniform SBA-15 particles, with a dimension of 400-800 nm, showed the decreasing in the pore volume, surface area, and pore diameter after modification process which is as a results of incorporating imidazole groups onto the pores of SBA-15. Afterward, catalytic activity of SBA-IL was investigated in the synthesis of 2,3-dihydroquinazolinones under solvent free condition. Manuscript profile

Mesoporous silica LUS-1 (Laval University Silica) was successfully functionalized by propyl sulfonic acid and was used as a recyclable catalyst for the synthesis of acridine-1,8-diones via a pseudo four component reaction of aromatic aldehydes, dimedone and ammonium acetate (or anilines). The excellent yields, short reaction time, simple work-up procedure, and environmentally friendly conditions are advantages of this method. All synthesized compounds were screened for antimicrobial and antifungal activities. Only compound 3e exhibited activity against Bacillus subtilis. Manuscript profile

SBA-15 was prepared and then functionalized with N-methyl-N’-propyltrimethoxysilyl imidazolium chloride as ionic liquid moiety. The ionic liquid functionalized SBA-15 (SBA-IL) was characterized by different analytical techniques including FT-IR, N2 adsorption-desorption, TGA and SEM image. According to the obtained results it was found that the organic groups were grafted onto the pores of SBA-15 because its pore size and BET surface dropped after modification step. Then, it was used as an efficient nanoreactor in the synthesis of biologically active henna based benzochromene derivatives under solvent‐free conditions. Consequently, the catalyst acted efficiently under solvent free system and gave the products in high yields and short reaction times. Some of the obtained products exhibited antibacterial activities as well as tetracycline. Manuscript profile

A Simple and efficient method for synthesis of tetrahydropyrimido[4,5-b]quinoline derivatives via three component reaction of aromatic aldehydes, dimedone and 6-amino uracil derivatives using a catalytic amount of sulfonic acid functionalized nanoporous silica (SBA-15-Pr-SO3H) is described. The advantages of this method are easy and clean work-up, high yield, mild reaction condition, reusable catalyst and environmentally benign solvents. Antibacterial and antifungal activities of synthesized compounds were measured against gram positive, gram negative bacteriaand fungus. Only compounds 4c and 4g showed activity against Staphylococcus aureus. Manuscript profile

Bis(indolyl)methanes are important group of bioactive metabolites of terrestrial and marine regions. They were synthesized by different methods. Herein, a clean, one-pot synthesis of bis(indolyl)methane derivatives by cyclo-condensation reaction of indole and various aldehydes using Sulfonic acid functionalized silica (SiO2-Pr-SO3H) in aqueous media is reported. The advantages of this new method were simple operation, good yields, short reaction times and easy work-up. Sulfonic acid functionalized silica as an efficient heterogeneous solid acid catalyst could be prepared by simple operation from commercially available cheap starting materials such as silica. It catalyzes various organic reactions and could be easily removed, recovered and reused without significant loss of activity. Manuscript profile

Sulfonic acid functionalized nanoporous silica (SBA-Pr-SO3H) with a pore size of 6 nm catalyzed three component coupling of aromatic aldehydes, urea and ethyl acetoacetate to afford the corresponding dihydropyrimidinones under solvent free condition. This new protocol for Biginelli reaction has important advantages such as green synthesis, short reaction time, easy isolation and high yields of products and reusability of the catalyst. SBA-Pr-SO3H was proved to be an efficient heterogeneous nanoporous solid acid catalyst which could be easily handled and removed from the reaction mixture by simple filtration and can be recovered and reused for several times without any loss of activity. Manuscript profile

The acidic agent (SO3H) was stabilized on the silica coated Fe3O4 magnetic nanoparticles to produce Fe3O4@SiO2@Pr-SO3H, as a heterogeneous acidic catalyst, was designed, and then fully studied and characterized by FT-IR, XRD, TGA, DTA, TEM, and SEM analysis. Subsequently, the catalytic activity of Fe3O4@SiO2@PrSO3H was investigated by the one-pot four- component condensation reaction between 1,3-indandione, aromatic aldehydes, acetophenone or propiophenone and ammonium acetate under the solvent-free condition at 80 ℃. The main advantages of this magnetic and heterogeneous acidic catalyst are high product yields, being environmentally benign, short reaction times, and easily separated from the reaction mixture using an external magnet. Manuscript profile

در این پژوهش، سیلیکای نانومتخلخل SBA-15 با 3-[2-(2-آمینواتیل آمینو) اتیل‌آمینو] پروپیل‌تری‌متوکسی‌سیلان اصلاح شد. سپس، با پیوند مشتقی از فلوئورن بر سطح داخلی آن، سیلیکای نانومتخلخل SBA-15 عامل‌دار شده با مشتق تری‌آمین فلوئورن تهیه شد. برای شناسایی نمونه‌ها روش‌های پراش پرتو ایکس (XRD)، جذب - واجذب گاز نیتروژن و طیف‌سنجی FTIR به‌کار گرفته شدند. سپس، قابلیت این ترکیب در استخراج کاتیون‌های نقره از محلول‌های آبی موردبررسی قرار گرفت. طیف‌سنجی جذب اتمی شعله‌ای برای تعیین غلظت یون‌ها در محلول به‌کار گرفته شد. اثر متغیرهایی مانند مقدار جاذب، زمان تماس، pH، غلظت یون فلزی و حضور یون‌های دیگر در محیط بررسی شدند. یون‌های نقره با استفاده از mg‌10 میلی‌گرم جاذب و پس از10 دقیقه هم‌خوردن، به‌طور کامل استخراج شدند. داده‌های جذب با هم‌دماهای لانگمویر و فرندلیچ تجزیه و تحلیل و مشخص شد فرایند جذب از مدل هم‌دمای لانگمویر پیروی می‌کند. بیش‌ترین ظرفیت جاذب (8/1±)14/357 میکروگرم نقره به ازای هر میلی‌گرم جاذب SBA-15 عامل‌دار شده به‌دست آمد. درنهایت، جاذب به‌طور موفقیت‌آمیزی در استخراج نقره از محلول عکاسی به‌کار برده شد. Manuscript profile