Air pollution is the result of the emission of chemicals, particulate matter, and biologic material into the atmosphere, which caused adverse effects on the environment and health. Major air pollutants that threaten human health are carbon monoxide, Nitrogen oxide, ozone, Sulfur dioxide, chemical vapors, and particulate matter. Air pollution is an important risk factor for cardiovascular health, therefore in this review article; we discuss air-polluting particles and the adverse effects of them on cardiovascular disease. Manuscript profile