Study on the effect of Savory)Saturejakhuzestanica(essential oil and Polysorb toxin-binder against experimental aflatoxicosis in Japanese quail
Subject Areas :
Veterinary Clinical Pathology
homa arak
1
,
mohammadamir karimitorshizi
2
,
shaban rahimi
3
1 - دانشجوی کارشناسی ارشد پرورش و تولید طیور، دانشگاه تربیت مدرس، تهران، ایران.
2 - استادیار گروه پرورش و تولید طیور، دانشگاه تربیت مدرس، تهران، ایران.
3 - استاد گروه پرورش و تولید طیور، دانشگاه تربیت مدرس، تهران، ایران
Received: 2013-12-08
Accepted : 2014-03-03
Published : 2013-11-22
Keywords:
liver,
Aflatoxin,
pathology,
<i>Saturejakhuzestanica<i>,
Polysorb,
Abstract :
Anti-aflatoxicosis potential of dietary supplementation of savory essential oil and a commercial mycotoxin binder (Polysorb) was investigated by study of some internal organ weights, lipid oxidation of meat and liver lesions. A total of 144 male 21 days old Japanese quails were divided into six treatments and 4 replicates (6 birds in each replication)and treated for 10 wks as follows: A-Negative control, B-Positive control-fed diet contaminated with aflatoxin B1 (2.5 PPM), C- Contaminated feed+300 PPM savory essential oil,D-Contaminated feed+ 600 PPM savory essential oil, E- Contaminated feed+ 900 PPM savory essential oil, F- Contaminated feed+ 2.5 g/kg Polysorb. At the end of the fourth and tenth weeks of experiment, two birds from each cage were randomly euthanized and relative weights of liver, spleen and bursa offabricius were determined and tissue samples of the liver were taken. The lipid oxidation in fresh and refrigerator meat samples were determined at the end of experiment. Use of 600 PPM of savory essential oil reduced the effects of aflatoxin on weights of bursa of fabricius and spleen. Highly intense fatty changes, large and small foci of hepatocellular degeneration and portal fibrosis caused by aflatoxin were observed in non-treated aflatoxicosis induced birds (group B). It seems that dietary supplementation of 600 PPM of savory essential oil and Polysorb can effectively reduce the toxic effects of aflatoxin B1 in Japanese quails.
References:
عظیمی، ج.، کریمی ترشیزی، م.، علامه، عا.، اهری، ح. و باقرزاده، ف. (1391). تاثیر افزودن دو ماده جاذب و زئولیت طبیعی به خوراک آلوده به آفلاتوکسین B1 بر عملکرد و سیستم ایمنی جوجههای گوشتی، مجله پژوهشهای علوم دامی ایران، دوره 4، شماره4، صفحات: 297-292.
شریعتمداری، ف و محیطی اصل، م. (1387). افزودنی خوراک دام، طیور و آبزیان. مرکز نشر آثار علمی دانشگاه تربیت مدرس، تهران، صفحه: 43.
Ahmadvand, H., Tavafi, M., Shahsavari, G., Khosrobeigi, A., Bagheri, S. and Abdolahpour, F. (2013).Hypolipidemic and antiatherogenic effects of Satureja khozestanica essential oil in Alloxan- Induced type 1 diabetic rats. Zahedan Journal of Research in Medical Sciences, 15(8):26-29.
Alpsoy, L. (2010). Inhibitory effect of essential oil on aflatoxin activities. Journal of Biotechnology, 9(17): 2474-2481.
Amanlou, M., Dadkhah, F., Salehnia, A. and Farsam, H. (2005). An anti-inflammatory and anti-nociceptive effects of hydroalcoholic extract of Satureja khuzistanica jamzad extract. Journal of Pharmaceutical Sciences, 8(1):102-106.
Ayoub, M.M., El-Far, A.H., Taha, N.M., Korshom, M.A., Mandour, A.A., Abdel-Hamid, H.S. et al., (2011). The biochemical protective role of some herbs against aflatoxicosis in ducklings: I. TURMERIC, Lucrari Stiintifice Journal, 55: 150-159.
Barmase, B.S., Devegowda, G. and Devurkar, U. (1990). Reversal of aflatoxicosis through dietary absorbents in broiler chickens. Proc. XIII National Symposium of Indian Poultry Science Association held at Bombay, 20-22, Dec.
Blount, W.P. (1961).Turkey "X" disease. Journal of British Turkey Federation,9 (52):52-61.
Botsoglou, N.A., Florou Paneri, P., Christaki, E., Fletouris, D.J. and Spais, A.B. (2002). Effect dietary oreganoessential oil on lipid oxidation in raw and cooked chicken during refrigerated storage. Meat Science, 62(2):259-265.
Collins, A.R. (2004). The comet assay for DNA damage and repair principles, applications and limitations. Molecular Biotechnology, 26(3): 249-261.
Denli, M. and Okan, F. (2007). Efficacy of different adsorbent in reducing the toxic effects of aflatoxin B1 in broiler diets. South African Journal of Animal Science, 36(4): 222-228.
El-Nkeety, A.A., Mohamed, A.S., Hassan, N.S., Aly, S.E. and Abdel-Wahhab, M.A. (2011). Antioxidant properties of Thymus vulgaris oil against aflatoxin- induct oxidative stress in male rats. Toxicon, 57(7-8): 984-991.
Govaris, A., Botsoglou, E., Florou Paneri, P., Moutas, A. and Papageorgiou, G. (2005). Dietary supplementation of oregano essential oil and tocopheryl acetate on microbial growth and lipid oxidation of turkey breast fillets during storage. Poultry Science, 49(12):969-975.
Hsieh, D.P.H. (1985). An assessment of liver cancer risk posed by aflatoxin B1 in Western world. Trichothecenes and other Mycotoxins, 11: 369-383.
Huff, W. E. and Doerr, J. A. (1980). Synergism between aflatoxin and OA in broiler chickens. Poultry Science, 60(3): 550-555.
Iqbal, Q.K., Rao, P.V. and Reddy, S.J.(1983). Dose-response relationship ofexperimentally induced aflatoxicosis incommercial layers. Animal Science, 53(11):1277-1280.
Kalaiselvi, T. and Panneersalvam, C. (1998). Effect of L-carnitine on the status of lipid peroxidation and antioxidants in aging rats. Journal of Nutritional Biochemistry, 9(10): 575-581.
Karaman, M., Basmacioglu, H., Ortatatli, M. and Oguz, H. (2005). Evaluation of the detoxifying effect of yeast glucomannan on aflatoxicosis in broiler as assessed by gross examination and histopathology. British Poultry Science, 46(3): 394-400.
Leeson, S., Diaz, G.J. and Summres, J.D. (1995). Poultry Metabolic Disorders and Mycotoxins. University Books. Guelph, Ontario. Canada.
Magnoli, A.P., Monge, M.P., Nazar, F.N., Magnoli, C.E., Cavagieri, L.R., Bagnis, G., et al., (2012).Combined effects of aflatoxin B1 and corticosterone treatment on selected performance indices an liver histopathology in Japanese quail, Poultry Science, 91(2): 354-361.
Magnoli, A.P., Texeira, M., Rosa, R.C.A., Miazzo, R.D., Cavaglieri, L.R., Magnoli, C.E., et al., (2011). Monensin affects the aflatoxin-binding ability of a sodium bentonite. Poultry Science, 90: 352–357.
Miazzo, R., Rosa, C.A.R., De Queiroz Carvalho, E.C., Magnoli, C., Chiacchiera, S.M., Palacio, G., et al., (2000). Efficacy of synthetic zeolite to reduce the toxicity of aflatoxin in broiler chickens, Poultry Science, 79(1): 1-6.
Oguz, H., Hadimli, H.H., Kurtoglu Vand Erganiş, O. (2003). Evaluation of humoral immunity of broilers during chronic aflatoxin (50 and 100 ppb) and clinoptilolite exposure. Revista de Medicina Veterinaria, 154(7): 483-486.
Oguz, H., Kececi, T., Birdane, Y.O., Onder, F. and Kurtoglu, V. (2000). Effect of clinoptilolite on serum biochemical and haematological characters of broiler chickens during experimental aflatoxicosis. Research in Veterinary Science, 69(1): 89-93.
Raju, M.V. and Devegowda, G. (2000). Influence of esterified glucomannan on performance and organic morphology, serum biochemistry and hematology in broilers exposed to individual and combined mycotoxicosis (aflatoxin, ochratoxin and T-2 toxin). British Poultry Science, 41: 640-650.
Richard, T L., Thurston, J.R. and Pier, A.C. (1975). Mycotoxin-Induced Alterations in Immunity. In: Microbiology, Schlessinger, D. ed., American Society of Microbiologist, Washington, D. C, pp:388-396.
Robens, J.F. and Richard, J.L. (1992). Aflatoxins in animal and human health. A Review. Environmental Contamination and Toxicology, 127: 69-94.
Rosa, C.A.R., Miazzo, R., Magnoli, C., Salvano, M., Chiacchiera, S.M., Ferrero, S., et al., (2001). Evaluation of the efficacy of bentonite from the South of Argentina to ameliorate the toxic effects of aflatoxin in broilers. Poultry Science, 80(2): 139-144.
SAS (1990). SAS/STATR User's guide, release 6.03 edition. SAS institute Inc., Cary, NC.
Schell, T.C., Lindemann, M.D., Kornegay, E.T. and Blodgett, D.J. (1993). Effects of feeding aflatoxin-contaminated diets with and without clay to weanling and growing pigs on performance, liver function, and mineral metabolism. Animal Science, 71(5): 1209-1218.
Shen, S.Q., Zhang, Y., Xiang, J.J. and Xiong, C.L. (2007). Protective effect of curcumin against liver warm ischemia/reperfusion injury in rat model is associated with regulation of heat shock protein and antioxidant enzyme. World Journal of Gastroenterology,13(13):1953-1961.
Sherif, O., Salama Emad, E. and Abdel-Wahhab, M.A. (2009).Mycotoxins and child health: the need for health risk assessment. International Journal of Hygiene and Environmental Health, 212(4): 336-347.
Shi, Y.H., Xu, Z.R., Feng, J.L. and Wang, C.Z. (2006). Efficacy of modified montmorillonite nanocomposite to reduce the toxicity of aflatoxin in broiler chicks. Animal Feed Science and Technology, 129(1): 138-148.
Shotwell, O.L., Hesseltine, C.V., Stubblefield, R.D. and Sorenson, W.G. (1966). Production of aflatoxin on rice. Applied and Environmental of Microbiology, 14(3): 425-428.
Shukla, P.K., Khanna, V.K., Khan, M.Y.and Srimal, R.C. (2003). Protective effect of curcuminagainst lead neurotoxicity in rat. Human and Experimental Toxicology, 22(12): 653-658.
Smith, J.E. and Hamilton, P.B. (1970). Aflatoxicosis in the broiler chicken. Poultry Science, 49(1):207-215.
Yarru, L.P., Settivari, R.S., Gowda, N.K.S., Antoniou, E., Ledoux, D.R. and Rottinghaus, G.E. (2009). Effects of turmeric (Curcuma longa) on the expression of hepatic genes associated with biotransformation, antioxidant, and immune systems in broiler chicks fed aflatoxin. Poultry Science, 88(12): 2620-2627.
