Comparative study of the effect of Immunowall and Avilamycin on antibody titre against Newcastle B1 vaccine in broiler chickens

Subject Areas : Veterinary Clinical Pathology

افشین Zakeri ¹ , سعید Charkhkar ² , Sh Zakeri ³ , بهرام Reihani ⁴

1 - Department of Animal Sciences, Faculty of Agriculture, Islamic Azad University of Tabriz, Tabriz, Iran
2 - Department of Clinical Sciences, Faculty of Veterinary Medicine, Islamic Azad University, Science & Research Campus, Tehran, Iran
3 - Graduate of Veterinary Medicine, Veterinary Faculty, Islamic Azad University, Science & Research Campus, Tehran, Iran
4 - Graduate of Veterinary Medicine, Veterinary Faculty, Islamic Azad University, Science & Research Campus, Tehran, Iran

Received: 2007-11-08 Accepted : 2008-02-21 Published : 2007-11-22

Keywords: broiler chickens, : Humoral immunity, Avilamycin, Immunowall (MOS),

Abstract :

     The purpose of the present study was to comparatively investigate the effect of Avilamycin and Immunowall on the improvement of humoral immunity in boiler chickens. In this study, 360 cobb broiler chickens were divided into three similar groups of 120 chickens with four replicates of 30 chickens in each group. In the first and second experimental groups, 1 kg/ton of Immunowall and Avilamycin respectively were added to the basic diet while in the third control group only the basic diet was used. On days 9, 17 and 25 of the breeding period (corresponding to 1 day before and 7 and 14 days after the first Newcastle B1 vaccination), 40 chickens were randomly chosen in each experimental group, their blood samples collected, and then serum antibody titres of these chickens against the Newcastle vaccine were measured by HI test. After stastistical analysis using ANOVA and Duncans’s multiple range test, the results of serum antibody titres by HI test on day 9 of the breeding period was not statistically significant. The results of HI test on day 17 of the breeding period (5.01 ± 0.32, 5.27 ± 0.27 and 5.13 ± 0.20 in the control and experimental groups 1 and 2 respectively) was also statistically not significant. The HI test results on day 25 of the breeding period (5.04 ± 0.44, 5.87 ± 0.47 and 5.61 ± 0.41 in the control and experimental groups 1 and 2 respectively) indicated significant statistical differences (P<0.05) between experimental groups 1 and 2 and the conrol group. However, there were no significant differences between the two experimental groups although serum antibody titres in experimental group 1 (Immunowall) showed 0.26 log increase compared to experimental group 2 (Avilamycin). Immunowall as a natural product is notably capable of improving anti B1 antibody production in response to Newcastle B1 vaccine and as it does not leave any drug residues in poultry meat, it can be a suitable alternative to growth promoting generation of antibiotics.  

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