A review of oxidative stress in diabetic patients with the approach of exercise training
Subject Areas : Physical Activity and Health
Pouria Ahmadi
1
,
Mehran Ghahramani
2
1 - Department of Exercise Physiology, Eslamabad-e-gharb Branch, Islamic Azad University, Eslamabad-e-gharb, Iran
2 - Department of Exercise Physiology, Gilan-E-Gharb Branch, Islamic Azad University, , Gilan-E-Gharb, Iran
Keywords: Diabetes mellitus, Oxidative stress, free radicals, ROS,
Abstract :
Introduction: The consequence of the oxidative stress process is the overproduction of free radicals, which are toxic products of oxygen metabolism and cause damage to different part of the cell, such as DNA and membrane and play a major role in the pathogenesis of diabetes. This article examines information about the role of oxidative stress in diabetic patients and the effect of exercise training on this process in this type of diseases. Methods: To carry out the present research, from the keywords found in more than 43 valid researches in various specialized sites, such as: Google scholar, Science Direct and articles in the journals: Experimental diabetes research, Med Sci Monit, MDPI which were previously in this field such as oxidative stress, ROS and…were done. Findings: The production of reactive oxygen species and lipid peroxidation increases in diabetic patients, the studies in this research show that exercise training can increase the activity of antioxidant systems. Exercise helps to restraint the effects of diabetes in cell damage. Conclusion: Exercise training cause to control oxidative stress in patients with diabetes and contrast with over levels of its.
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