Enzyme Inhibitory Activity of Certain Vegetables Indigenous in Iran as Potential Antiandrogens

Subject Areas : food microbiology

A. Sharifan ¹ ( Associate Professor of the College of Food Science and Technology, Science and Research Branch, Islamic Azad University, Tehran, Iran. )
A. Hajhoseini ² ( Ph. D. Research Student of the College of Food Science and Technology, Science and Research Branch, Islamic Azad University, Tehran, Iran. )
M. Bakhtiari ³ ( Director Manager of Shadara Caspian Company, Tehran, Iran. )

Received: 2017-09-07 Accepted : 2017-09-22 Published : 2018-01-01

Keywords:

References:

Acquaviva, R., Di Giacomo, C., Sorrenti, V., Galvano, F., Santangelo, R., Cardile, V. & Vanella, L. (2012). Antiproliferative effect of oleuropein in prostate cell lines. International Journal of Oncology, 41(1), 31-80.

Ahari, D. S., Kashi, A. K., Hassandokht, M. R., Amri, A. & Alizadeh, K. (2009). Assessment of drought tolerance in Iranian fenugreek landraces. International Journal of Food, Agriculture and Environment, 7, 414-419.

Ahmed, H. M. (2016). Ethnopharmacobotanical study on the medicinal plants used by herbalists in Sulaymaniyah Province, Kurdistan, Iraq. Journal of Ethnobiology and Ethnomedicine, 12(8), 1-17.

Azimi, M., Sharifan, A. & Ghiasi Tarzi, B. (2017). The Use of Pistacia khinjuk Essential Oil to Modulate Shelf‐Life and Organoleptic Traits of Mechanically Deboned Chicken Meat. Journal of Food Processing and Preservation, 41(2). e12814.

Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry, 72 (1-2), 248-254.

Brawley, O. W. (2003). Hormonal prevention of prostate cancer. Urol Oncol, 21(1), 67-72.

Didarshetaban, M. B., Pour, S. & Reza, H. (2013). Fenugreek (Trigonella foenum-graecum L.) As a Valuable Medicinal Plant. International Journal of Advanced Biological and Biomedical Research, 1(8), 922-931.

Ghanbari, R., Anwar, F., Alkharfy, K. M., Gilani, A. H. & Saari, N. (2012). Valuable nutrients and functional bioactives in different parts of olive (Olea europaea L.)-a review. International Journal of Molecular Sciences, 13(3), 3291-3340. doi: 10.3390/ijms13033291

Goswami, P., Khale, A. & Ogale, S. (2012). Natural remedies for polycystic ovarian syndrome (PCOS): a review. International Journal of Pharmaceutical and Phytopharmacological Research, 1(6), 396-402.

Gupta, P. K., Chauhan, N. S., & Pathak, A. (2013). Effect of Trigonella foenum-graecum Linn. (seeds) and Butea monosperma Lam. (flowers) on chemotherapy-induced alopecia. Spatula DD, 3(3), 121-125.

Hajheydari, Z., Jamshidi, M., Akbari, J. & Mohammadpour, R. (2007). Combination of topical garlic gel and betamethasone valerate cream in the treatment of localized alopecia areata: a double-blind randomized controlled study. Indian Journal of Dermatology, Venereology and Leprology, 73(1), 29-32.

Hossain, M. S., Urbi, Z., Evamoni, F. Z., Zohora, F. T., & Rahman, K. M. H. (2016). A Secondary Research on Medicinal Plants Mentioned in the Holy Qur’an. J Med Plants, 3(59), 81-97.

Karioti, A., Chatzopoulou, A., Bilia, A. R., Liakopoulos, G., Stavrianakou, S. & Skaltsa, H. (2006). Novel Secoiridoid glucosides in Olea europaea leaves suffering from boron deficiency. Bioscience, Biotechnology, and Biochemistry, 70(8), 1898-1903. doi: 10.1271/bbb.60059

Krieg, M., Weisser, H. & Tunn, S. (1995). Potential activities of androgen metabolizing enzymes in human prostate. The Journal of Steroid Biochemistry and Molecular Biology, 53(1-6), 395-400.

Levy, M. A., Brandt, M., Sheedy, K. M., Holt, D. A., Heaslip, J. I., Trill, J. J. & Bergsma, D. J. (1995). Cloning, expression and functional characterization of type 1 and type 2 steroid 5 alpha-reductases from Cynomolgus monkey: comparisons with human and rat isoenzymes. The Journal of Steroid Biochemistry and Molecular Biology, 52(4), 307-319.

Lieberman, R. (2003). Evolving strategies for prostate cancer chemoprevention trials. World Journal of Urology, 21(1), 3-8. doi: 10.1007/s00345-003-0317-4

Luo, H. (2011). Extraction of antioxidant compounds from olive (Olea europaea) leaf. Master of Science, Massey University.  

Maluki, A. H., Mahmood, T. A. & Hadi, Q. N. (2009). Treatment of alopecia areata with topical garlic extract. Kufa Medical Journal, 12(1), 312-318.

Marchese, M. (2012). Polycystic ovarian syndrome: a natural treatment approach. Environmental Medicine Update, 66-68.

McRae, M. P. (2006). A review of studies of garlic (Allium sativum) on serum lipids and blood pressure before and after 1994: does the amount of allicin released from garlic powder tablets play a role? Journal of Chiropractic Medicine, 4(4), 182-190.

Mehrafarin, A., Qaderi, A., Rezazadeh, S. H., Naghdi Badi, H., Noormohammadi, G. H. & Zand, E. (2010). Bioengineering of important secondary metabolites and metabolic pathways in fenugreek (Trigonella foenum-graecum L.). Journal of Medicinal Plants, 3(35), 1-18.

Nahata, A. & Dixit, V. K. (2014). Evaluation of 5α‐reductase inhibitory activity of certain herbs useful as antiandrogens. Andrologia, 46(6), 592-601.

Noumi, E. & Kolaipla, B. (2011). Prostatic illnesses: epidemiology and treatment with medicinal plants at Maroua (Cameroon). International Journal of Research in Ayurveda and Pharmacy, 2(3), 822-829.

Ryan, D. & Robards, K. (1998). Critical Review. Phenolic compounds in olives. The Analyst, 123(5), 31R-44R.

Sun, Z. Y., Zheng, W. J., & Feng, J. (1998). A convenient and rapid method to study enzymatic kinetics of steroid 5a-reductase inhibitors. Indian Journal of Pharmacology, 30(4), 257-262.

Suntar, I. P., Akkol, E. K. & Baykal, T. (2010). Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L. Journal of Medicinal Food, 13(2), 352-356. doi: 10.1089/jmf.2009.0067

Urysiak-Czubatka, I., Kmiec, M. L. & Broniarczyk-Dyla, G. (2014). Assessment of the usefulness of dihydrotestosterone in the diagnostics of patients with androgenetic alopecia. Postȩpy Dermatologii i Aalergologii, 31(4), 207-215. doi: 10.5114/pdia.2014.40925

Yadav, R. & Kaushik, R. (2011). A study of phytochemical constituents and pharmacological actions of Trigonella foenum-graecum: A review. International Journal of Pharmacy and Technology, 3(2), 1022-1028.

Zargari, A. (1997). Iranian medicinal plants. Tehran Tehran University Publications.

Zhu, Y. S. & Sun, G. H. (2005). 5alpha-Reductase Isozymes in the Prostate. Journal of Medical Sciences, 25(1), 1-12.