A Comparative Study Concerned with the Prevalence of Iron Deficiency Anemia in Infected and Non-Infected Persons with Helicobacter Pylori in the City of Kashan

Subject Areas : Microbiology

M. H. Arabi ¹ , M. Taghizadeh ² , S. M. Takhte Firozeh ³ , F. Baharloei ⁴ , M. Pourbabaei ⁵ , M. Mahloji ⁶ , H. Akbari ⁷ , Sh. Alvani ⁸

1 - دانشیار گروه بیوشیمی، دانشگاه علوم پزشکی کاشان، ایران
2 - دانشیار علوم تغذیه، مرکز تحقیقات بیوشیمی و تغذیه در بیماری‌های متابولیک، دانشگاه علوم پزشکی کاشان، ایران
3 - عضو کمیته تحقیقات دانشجویی، دانشگاه علوم پزشکی هرمزگان، بندرعباس، ایران
4 - کارشناس گروه پرستاری داخلی جراحی، دانشکده پرستاری، دانشگاه علوم پزشکی کاشان، ایران
5 - دانشجوی کارشناسی ارشد گروه میکروبیولوژی و ایمنولوژی، دانشگاه علوم پزشکی کاشان، ایران
6 - کارشناس مامائی، مرکز تحقیقات گیاهان دارویی باریج اسانس، ایران
7 - استادیار گروه آموزشی آمار زیستی و اپیدمیولوژی، دانشگاه علوم پزشکی کاشان، ایران
8 - کارشناس ارشد سم شناسی، آزمایشگاه فیزیولوژی و فارماکولوژی، دانشگاه علوم پزشکی کاشان، ایران

Received: 2016-02-21 Accepted : 2016-02-21 Published : 2016-03-20

Keywords: Helicobacter Pylori infection, Iron Deficiency Anemia, Serum Ferritin,

Abstract :

Introduction: Helicobacter pylori is a common infectious disease that has numerous sideeffects. The impact of these infections because of decreased iron absorption in reducinggastric acid secretion and the consequent anemia has been mentioned. In this study, acomparative study concerned with the prevalence of iron deficiency anemia in infected andnon-infected persons with Helicobacter pylori in the city of Kashan have been studied.Materials and Methods: The people who were referred to the laboratory to evaluate theantibody IGg were 412 people of whom 229 were infected and 183 were non-infected. 3 ml ofblood samples were taken to measure the serum ferritin (SF) and complete blood count (CBC).Results: The mean and standard deviation of competing blood counts based on the status ofinfection with H. pylori showed that the serum ferritin (SF) in the infected patients was lessthan the non- infected persons (p =0.04) and this difference based on gender was significant inwomen (p <0.001). The indices showed that the SF in all age groups of infected persons isLess than non infected persons and this difference in persons over 60 was also significant (p<0.001). Also in the women over 30, the mean of SF in infected persons was less than the noninfected persons and this difference was significant (p<0.05).Conclusion: The results showed that the amount of SF of H. pylori infected womenespecially in those over 30 significantly has decreased that might be due to the impairment of iron absorption in the infected persons.