Antimicrobial effect of ethanolic extract of orange peel against bacteria isolated from burn infection

Subject Areas : Journal of plant ecophysiology

Zeinab Fotoohiyan ¹ , Hadis Shahrokhi sardo ²

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Received: 2024-11-24 Accepted : 2024-11-28 Published : 2024-05-04

Keywords: Antibiotics, Plant extract, Orange peel, Antibacterial, Jiroft,

Abstract :

Objective: A burn is a type of damage to the skin. In this skin damage, the first defense barrier of the body is destroyed, and the patient's wound becomes the best environment for the growth of bacteria. Nowadays, medicinal plants are used to deal with bacteria. In this research, in order to investigate the effect of ethanolic extract of orange peel on bacteria isolated from the wounds of burn patients in Jiroft hospitals and compare them with selected antibiotics, in 2022. For this purpose, after collecting the orange peel of Thomson variety, its extract was performed by percolation method and after isolation, the bacteria causing the infection were identified using morphological and biochemical tests. Then, the effect of ethanolic extract of orange peel and common antibiotics against bacteria was investigated. The results showed that Pseudomonas aeruginosa (52%), Staphylococcus aureus (37%) and Escherichia coli (11%) frequency had the most role in burn wound infections. And the orange peel extract had a better antibacterial effect against bacteria compared to cefixime and azithromycin antibiotics, so that the diameter of the inhibition zone of orange peel extract in S. aureus at 300.12 mg/ml was 31.22 mm and the antibiotic cefixime and azithromycin were 17.23 and 27.52 mm, respectively. Therefore we can use orange peel extract instead of antibiotics and chemical drugs to fight the burn infection bacteria.

 

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